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Route of antibiotic prophylaxis for prevention of cerebrospinal fluid‐shunt infection

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Appendices

Appendix 1. Cochrane Library

#1hydrocephal*:ti,ab,kw

#2MeSH descriptor: [Hydrocephalus] explode all trees

#3aqu?ductal stenos?s:ti,ab,kw

#4#1 or #2 or #3

#5MeSH descriptor: [Cerebrospinal Fluid Shunts] explode all trees

#6(shunt* or catheter*):ti,ab,kw

#7#5 or #6

#8#4 and #7

#9MeSH descriptor: [Anti‐Bacterial Agents] explode all trees

#10antibiotic* or anti‐bacterial or antibacterial or anti near/4 bacterial:ti,ab,kw

#11MeSH descriptor: [Antibiotic Prophylaxis] explode all trees

#12MeSH descriptor: [Vancomycin] explode all trees

#13vancomycin:ti,ab,kw

#14vancomicin:ti,ab,kw

#15MeSH descriptor: [Rifampin] explode all trees

#16rifampicin:ti,ab,kw

#17rifampin:ti,ab,kw

#18MeSH descriptor: [Gentamicins] explode all trees

#19gentam?cin:ti,ab,kw

#20MeSH descriptor: [Methicillin] explode all trees

#21methicillin or meticillin or methycillin or metycillin:ti,ab,kw

#22MeSH descriptor: [Cefazolin] explode all trees

#23cephazolin*:ti,ab,kw

#24cefazolin*:ti,ab,kw

#25#9 or #10 or #11 or #12 or #13 or #14 or #15 or #16 or #17 or #18 or #19 or #20 or #21 or #22 or #23 or #24

#26[mh staphylococcus] or [mh streptococcus]

#27s. aureus:ti,ab,kw

#28st. aureus:ti,ab,kw

#29staphylococcus aureus:ti,ab,kw

#30s. epidermidis:ti,ab,kw

#31st. epidermidis:ti,ab,kw

#32staphylococcus epidermidis:ti,ab,kw

#33bacterial infection*:ti,ab,kw

#34bacterem*:ti,ab,kw

#35(gram‐negative bacterial infection*):ti,ab,kw

#36(gram negative bacterial infection*):ti,ab,kw

#37(gram‐positive bacterial infection*):ti,ab,kw

#38(gram positive bacterial infection*):ti,ab,kw

#39staphylococ* infection*:ti,ab,kw

#40streptococ* infection*:ti,ab,kw

#41(catheter‐related infection* or catheter‐associated infection* or catheter* infection or prosthes*‐related infection* or prosthes* infection*):ti,ab,kw

#42(shunt‐related infection* or shunt‐associated infection* or shunt* infection*):ti,ab,kw

#43MeSH descriptor: [Infection] this term only

#44MeSH descriptor: [Catheter‐Related Infections] this term only

#45MeSH descriptor: [Prosthesis‐Related Infections] explode all trees

#46MeSH descriptor: [Sepsis] explode all trees

#47sepsis or blood poisoning or shock or toxemia* or circulatory failure or pyohemia* or pyemia or pyaemia or septicemia or circulatory collapse:ti,ab,kw

#48MeSH descriptor: [Bacterial Infections] explode all trees

#49#26 or #27 or #28 or #29 or #30 or #31 or #32 or #33 or #34 or #35 or #36 or #37 or #38 or #39 or #40 or #41 or #42 or #43 or #44 or #45 or #46 or #47 or #48

#50#8 and #25 and #49

Appendix 2. MEDLINE

1 hydrocephal*.ti,ab,kf. (23714)

2 hydrocephalus/ or dandy‐walker syndrome/ or hydrocephalus, normal pressure/ (21817)

3 aqu?ductal stenos?s.ti,ab,kf. (674)

4 cerebrospinal fluid shunts/ or ventriculoperitoneal shunt/ (9913)

5 (shunt* or catheter*).ti,ab,kf. (235894)

6 exp Anti‐Bacterial Agents/ (636809)

7 exp Vancomycin/ (12005)

8 van?om?cin.ti,ab,kf,rn. (25325)

9 exp Rifampin/ (16257)

10 rifamp??in.ti,ab,kf,rn. (26494)

11 exp Gentamicins/ (18172)

12 gentam#cin.ti,ab,kf,rn. (24315)

13 exp Methicillin/ (3675)

14 met??cillin*.ti,ab,kf,rn. (29932)

15 exp Cefazolin/ (2584)

16 ce??azolin*.ti,ab,kf,rn. (4945)

17 (antibiotic* or anti‐bacterial or antibacterial or (anti adj4 bacterial)).ti,ab,kf. (333911)

18 exp Antibiotic Prophylaxis/ (11911)

19 exp Staphylococcus/ or exp streptococcus/ (157073)

20 (staphylococcus epidermidis or staphylococcus aureus).ti,ab,kf. (90371)

21 (s? aureus or s? epidermidis).ti,ab,kf. (34110)

22 (bacterial adj5 infection*).ti,ab,kf. (46788)

23 bacterem*.ti,ab,kf. (22597)

24 (gram‐negative adj4 bacterial adj4 infection*).ti,ab,kf. (1021)

25 (gram‐positive adj4 bacterial adj4 infection*).ti,ab,kf. (465)

26 staphylococ* infection*.ti,ab,kf. (6916)

27 ((shunt* or prosthes* or catheter*) adj4 infection*).ti,ab,kf. (10617)

28 pyohemia*.ti,ab,kf. (8)

29 py?emia*.ti,ab,kf. (161)

30 blood poisoning*.ti,ab,kf. (25)

31 (circulatory adj3 (collaps or failure)).ti,ab,kf. (2252)

32 shock.ti,ab,kf. (159681)

33 sepsis.ti,ab,kf. (80390)

34 toxemia*.ti,ab,kf. (5853)

35 septic?emia*.ti,ab,kf. (19623)

36 bacterial infections/ or meningitis, bacterial/ or gram‐negative bacterial infections/ or gram‐positive bacterial infections/ or staphylococcal infections/ or streptococcal infection/ or infection/ or catheter‐related infections/ or prosthesis‐related infections/ or sepsis/ or bacteremia/ or endotoxemia/ or shock, septic/ (284371)

37 1 or 2 or 3 (31047)

38 4 or 5 (238246)

39 37 and 38 (10565)

40 6 or 7 or 8 or 9 or 10 or 11 or 12 or 13 or 14 or 15 or 16 or 17 or 18 (802056)

41 19 or 20 or 21 or 22 or 23 or 24 or 25 or 26 or 27 or 28 or 29 or 30 or 31 or 32 or 33 or 34 or 35 or 36 (636632)

42 39 and 40 and 41 (397)

Appendix 3. Embase

1 hydrocephal*.ti,ab,kw. (30549)

2 aqu?ductal stenos?s.ti,ab,kw. (889)

3 brain ventricle peritoneum shunt/ or cerebrospinal fluid shunting/ (12536)

4 (shunt* or catheter*).ti,ab,kw. (327207)

5 hydrocephalus/ or brain aqueduct stenosis/ or brain ventricle dilatation/ or communicating hydrocephalus/ or congenital hydrocephalus/ or costello syndrome/ or dandy walker syndrome/ or normotensive hydrocephalus/ or obstructive hydrocephalus/ or walker warburg syndrome/ (43875)

6 exp antibiotic agent/ (1189546)

7 (antibiotic* or anti‐bacterial or antibacterial or (anti adj4 bacterial)).ti,ab,kw. (425175)

8 exp vancomycin/ or vancomycin derivative/ (75963)

9 van?om?cin.ti,ab,kw,rn. (80189)

10 exp rifampicin/ (80059)

11 rifamp??in.ti,ab,kw,rn. (83132)

12 exp gentamicin/ (95859)

13 gentam#cin.ti,ab,kw,rn. (99462)

14 exp meticillin/ (22727)

15 met??cillin*.ti,ab,kw,rn. (45463)

16 exp cefazolin/ (23856)

17 ce??azolin*.ti,ab,kw,rn. (24421)

18 exp antibiotic prophylaxis/ (26990)

19 exp staphylococcus/ or exp streptococcus/ (279482)

20 (staphylococcus aureus or staphylococcus epidermidis).ti,ab,kw. (110835)

21 s? aureus.ti,ab,kw. (40211)

22 s? epidermidis.ti,ab,kw. (5419)

23 (bacterial adj5 infection*).ti,ab,kw. (62753)

24 bacterem*.ti,ab,kw. (28575)

25 ((gram‐negative adj4 bacterial adj4 infection*) or (gram‐positive adj4 bacterial adj4 infection*)).ti,ab,kw. (1765)

26 staphylococ* infection*.ti,ab,kw. (4619)

27 ((catheter* or shunt* or prosthes*) adj4 infection*).ti,ab,kw. (15124)

28 sepsis.ti,ab,kw. (120941)

29 pyohemia*.ti,ab,kw. (4)

30 py?emia*.ti,ab,kw. (115)

31 septic?emia.ti,ab,kw. (21677)

32 blood poisoning*.ti,ab,kw. (25)

33 (circulatory adj3 (collaps or failure)).ti,ab,kw. (3161)

34 shock.ti,ab,kw. (199561)

35 toxemia*.ti,ab,kw. (3996)

36 bacterial infection/ or infection/ or bacterial meningitis/ or gram negative infection/ or gram positive infection/ or staphylococcus infection/ or streptococcus infection/ or endotoxemia/ or exp device infection/ (742628)

37 bacteremia/ or sepsis/ or septic shock/ or septicemia/ (216240)

38 1 or 2 or 5 (48510)

39 3 or 4 (331237)

40 38 and 39 (14764)

41 6 or 7 or 8 or 9 or 10 or 11 or 12 or 13 or 14 or 15 or 16 or 17 or 18 (1371513)

42 19 or 20 or 21 or 22 or 23 or 24 or 25 or 26 or 27 or 28 or 29 or 30 or 31 or 32 or 33 or 34 or 35 or 36 or 37 (1302104)

43 40 and 41 and 42 (909)