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Certolizumab pegol for induction of remission in Crohn's disease

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Appendices

Appendix 1. Search strategies

MEDLINE (inception to date)

1. random$.tw.

2. factorial$.tw.

3. (crossover$ or cross over$ or cross‐over$).tw.

4. placebo$.tw.

5. single blind.mp.

6. double blind.mp.

7. triple blind.mp.

8. (singl$ adj blind$).tw.

9. (double$ adj blind$).tw.

10. (tripl$ adj blind$).tw.

11 assign$.tw.

12. allocat$.tw.

13. randomized controlled trial/

14. or/1‐13

15. (exp animal/ or animal.hw. or nonhuman/) not (exp human/ or human cell/ or (human or humans).ti.)

16. 14 not 15

17. exp Crohn disease/ or Crohn*.mp.

18. (inflammatory bowel disease* or IBD).mp.

19. 17 or 18

20. 16 and 19

21. (CDP870 OR 'CDP 870' OR CDP‐870 OR 'certolizumab pegol' OR certolizumab OR cimzia).mp.

22. 20 and 21

EMBASE (inception to date)

1. random$.tw.

2. factorial$.tw.

3. (crossover$ or cross over$ or cross‐over$).tw.

4. placebo$.tw.

5. single blind.mp.

6. double blind.mp.

7. triple blind.mp.

8. (singl$ adj blind$).tw.

9. (double$ adj blind$).tw.

10. (tripl$ adj blind$).tw.

11 assign$.tw..

12. allocat$.tw.

13. crossover procedure/

14. double blind procedure/

15. single blind procedure/

16. triple blind procedure/

17. randomized controlled trial/

18. or/1‐17

19. (exp animal/ or animal.hw. or nonhuman/) not (exp human/ or human cell/ or (human or humans).ti.)

20. 18 not 19

21. exp Crohn disease/ or Crohn*.mp.

22. (inflammatory bowel disease* or IBD).mp.

23. 21 or 22

24. 20 and 23

25. exp certolizumab pegol/

26. (CDP870 OR 'CDP 870' OR CDP‐870 OR 'certolizumab pegol' OR certolizumab OR cimzia).mp.

27. 25 or 26

28. 24 and 27

CENTRAL (inception to date)

#1. crohn* OR IBD OR "inflammatory bowel disease*"

#2. CDP870 OR 'CDP 870' OR CDP‐870 OR 'certolizumab pegol' OR certolizumab OR cimzia

#3. #1 and #2

Cochrane IBD Group Specialized Register (inception to date)

#1 (CDP870 OR 'CDP 870' OR CDP‐870 OR 'certolizumab pegol' OR certolizumab OR cimzia).ti.

#2 Crohn.ti.

#3 1 and 2