Database

Time span

Search strategy

Cochrane Hepato‐Biliary Group Controlled Trials Register

Date will be given at review stage.

lamivudin* AND resistan* AND (chronic AND (hepatitis B OR hep B OR HBV))

Cochrane Central Register of Controlled Trials (CENTRAL)

Latest issue

#1 MeSH descriptor: [Lamivudine] explode all trees

#2 lamivudine

#3 #1 or #2

#4 resistan*

#5 MeSH descriptor: [Hepatitis B, Chronic] explode all trees

#6 (chronic and ('hepatitis B' or 'hep B' or HBV))

#7 #5 or #6

#8 #3 and #4 and #7

MEDLINE (Ovid SP)

1946 to the date of search.

1. exp Lamivudine/

2. lamivudine.mp. [mp=title, abstract, original title, name of substance word, subject heading word, keyword heading word, protocol supplementary concept, rare disease supplementary concept, unique identifier]

3. 1 or 2

4. resistan*.mp. [mp=title, abstract, original title, name of substance word, subject heading word, keyword heading word, protocol supplementary concept, rare disease supplementary concept, unique identifier]

5. exp Hepatitis B, Chronic/

6. (chronic and ('hepatitis B' or 'hep B' or HBV)).mp. [mp=title, abstract, original title, name of substance word, subject heading word, keyword heading word, protocol supplementary concept, rare disease supplementary concept, unique identifier]

7. 5 or 6

8. 3 and 4 and 7

9. (random* or blind* or placebo* or meta‐analys*).mp. [mp=title, abstract, original title, name of substance word, subject heading word, keyword heading word, protocol supplementary concept, rare disease supplementary concept, unique identifier]

10. 8 and 9

Embase (Ovid SP)

1974 to the date of search.

1. exp lamivudine/

2. lamivudine.mp. [mp=title, abstract, subject headings, heading word, drug trade name, original title, device manufacturer, drug manufacturer, device trade name, keyword]

3. 1 or 2

4. resistan*.mp. [mp=title, abstract, subject headings, heading word, drug trade name, original title, device manufacturer, drug manufacturer, device trade name, keyword]

5. exp hepatitis B/

6. (chronic and ('hepatitis B' or 'hep B' or HBV)).mp. [mp=title, abstract, subject headings, heading word, drug trade name, original title, device manufacturer, drug manufacturer, device trade name, keyword]

7. 5 or 6

8. 3 and 4 and 7

9. (random* or blind* or placebo* or meta‐analys*).mp. [mp=title, abstract, subject headings, heading word, drug trade name, original title, device manufacturer, drug manufacturer, device trade name, keyword]

10. 8 and 9

Science Citation Index Expanded (Web of Science)

1900 to the date of search.

#6 #5 AND #4

#5 TS=(random* or blind* or placebo* or meta‐analys*)

#4 #3 AND #2 AND #1

#3 TS=(chronic and ('hepatitis B' or 'hep B' or HBV))

#2 TS=(resistan*)

#1 TS=(lamivudine)