High‐dose chemotherapy followed by autologous haematopoietic cell transplantation for children, adolescents and young adults with metastatic Ewing sarcoma
Appendices
Appendix 1. Search strategy for Cochrane Central Register of Controlled Trials (CENTRAL)
1. For Ewing sarcoma, we will use the following text words:
ewing OR ewings OR ewing* OR ewing sarcoma OR peripheral neuroectodermal tumor OR peripheral neuroectodermal tumour OR peripheral neuroectodermal tumors OR peripheral neuroectodermal tumours OR primitive neuroectodermal tumor OR primitive neuroectodermal tumour OR primitive neuroectodermal tumors OR primitive neuroectodermal tumours OR Primitive Neuroepithelial Tumor OR Primitive Neuroepithelial Tumors OR Primitive Neuroepithelial Tumour OR Primitive Neuroepithelial Tumours OR Primitive Neuroepithelial Neoplasm OR Primitive Neuroepithelial Neoplasms OR PNET OR PNETs OR neuroepithelioma OR neuroepitheliomas OR (askin AND (tumor OR tumors OR tumour OR tumours))
2. For autologous haematopoietic cell transplantation, we will use the following text words:
bone marrow transplantation or bone marrow grafting or bone marrow cell transplantation or stem cell transplantation or stem cell transplantations or hematopoietic stem cell transplantation or haematopoietic stem cell transplantation or hematopoietic cell transplantation or haematopoietic cell transplantation or HSCT or HCT or peripheral blood stem cell transplantation or peripheral stem cell transplantation or autograft or autografts or transplantation, autologous or autotransplant or autotransplants or ABMT or PBSCT or transplant* or homolog* or autolog* or BMT or myeloablative therapy or myeloablative agonist or myeloablative agonists or myeloablativ* or mega therapy or stem cell rescue or bone marrow rescue or high‐dose therapy or high dose therapy or homograft or homografts or homologous transplantation or homologous transplantations or transplantations, homologous or transplantation, homologous or transplantations
Final search 1 and 2
The search will be performed in title, abstract or keywords
[*=zero or more characters]
Appendix 2. Search strategy for MEDLINE (PubMed)
1. For Ewing sarcoma, we will use the following MeSH headings and text words:
ewing OR ewings OR ewing* OR ewing sarcoma OR ewing's sarcoma OR "peripheral neuroectodermal tumor" OR "peripheral neuroectodermal tumour" OR "peripheral neuroectodermal tumors" OR "peripheral neuroectodermal tumours" OR "primitive neuroectodermal tumor" OR "primitive neuroectodermal tumour" OR "primitive neuroectodermal tumors" OR "primitive neuroectodermal tumours" OR "Primitive Neuroepithelial Tumor" OR "Primitive Neuroepithelial Tumors" OR "Primitive Neuroepithelial Tumour" OR "Primitive Neuroepithelial Tumours" OR "Primitive Neuroepithelial Neoplasm" OR "Primitive Neuroepithelial Neoplasms" OR "PNET" OR "PNETs" OR neuroepithelioma[tw] OR neuroepitheliomas[tw] OR neuroectodermal tumors, primitive, peripheral[Mesh:NoExp] OR neuroectodermal tumors, primitive[Mesh:NoExp] OR (askin AND (tumor OR tumors OR tumour OR tumours))
2. For autologous haematopoietic cell transplantation, we will use the following MeSH headings and text words:
bone marrow transplantation OR bone marrow grafting OR bone marrow cell transplantation OR stem cell transplantation OR stem cell transplantations OR hematopoietic stem cell transplantation OR haematopoietic stem cell transplantation OR hematopoietic cell transplantation OR haematopoietic cell transplantation OR HSCT OR HCT OR peripheral blood stem cell transplantation OR peripheral stem cell transplantation OR autograft OR autografts OR transplantation, autologous OR autotransplant OR autotransplants OR ABMT OR PBSCT OR transplant* OR homolog* OR autolog* OR BMT OR "myeloablative therapy" OR myeloablative agonist OR myeloablative agonists OR myeloablativ* OR "mega therapy" OR stem cell rescue OR bone marrow rescue OR "high‐dose therapy" OR "high dose therapy" OR homograft OR homografts OR homologous transplantation OR homologous transplantations OR transplantations, homologous OR transplantation, homologous OR transplantations
Final search 1 AND 2
[* = zero or more characters; tw = text word]
Appendix 3. Search strategy for EMBASE (Ovid)
1. ForEwing sarcoma, we will use the following Emtree terms and text words:
1. (ewing or ewings or ewing$).ti,ab.
2. exp Ewing sarcoma/
3. (ewing sarcoma or ewing's sarcoma).mp.
4. (PNET or PNETs).mp.
5. (peripheral neuroectodermal tumor or peripheral neuroectodermal tumors or peripheral neuroectodermal tumour or peripheral neuroectodermal tumours).mp.
6. (primitive neuroectodermal tumor or primitive neuroectodermal tumors or primitive neuroectodermal tumour or primitive neuroectodermal tumours).mp.
7. (primitive neuroepithelial tumor or primitive neuroepithelial tumors or primitive neuroepithelial tumour or primitive neuroepithelial tumours).mp.
8. neuroectoderm tumor/ or neuroepithelioma/ or (neuroepithelioma or neuroepitheliomas).mp.
9. (Primitive Neuroepithelial Neoplasm or Primitive Neuroepithelial Neoplasms).mp.
10. (askin and (tumor or tumors or tumour or tumours)).mp.
11. or/1‐10
2. For autologous haematopoietic cell transplantation, we will use the following Emtree terms and text words:
1. (bone marrow transplantation or bone marrow grafting).mp.
2. (bone marrow cell transplantation or stem cell transplantation or stem cell transplantations).mp.
3. (hematopoietic stem cell transplantation or haematopoietic stem cell transplantation or HSCT or HCT or peripheral blood stem cell transplantation).mp.
4. peripheral stem cell transplantation.mp.
5. (autograft or autografts).mp.
6. autograft/
7. (autologous transplantation or autotransplant or autotransplants).mp.
8. (BMT or ABMT or PBSCT).mp.
9. transplant$.mp.
10. (autolog$ or homolog$).mp.
11. myeloablative therapy.mp.
12. (myeloablative agonist or myeloablative agonists).mp.
13. myeloablativ$.mp.
14. mega therapy.mp.
15. (high‐dose therapy or high dose therapy).mp.
16. (stem cell rescue or bone marrow rescue).mp.
17. (homograft or homografts).mp.
18. (homologous transplantation or homologous transplantations).mp.
19. transplantations.mp.
20. or/1‐19
Final search 1 and 2
[mp = title, abstract, subject headings, heading word, drug trade name, original title, device manufacturer, drug manufacturer name; ti,ab = title, abstract; / = Emtree term; $=zero or more characters]
