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Cochrane Database of Systematic Reviews

Mycophenolate mofetil versus methotrexate for prevention of acute graft‐versus‐host disease in patients receiving allogeneic hematopoietic stem cell transplantation

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Information

DOI:
https://doi.org/10.1002/14651858.CD010280Copy DOI
Database:
  1. Cochrane Database of Systematic Reviews
Version published:
  1. 12 December 2012see what's new
Type:
  1. Intervention
Stage:
  1. Protocol
Cochrane Editorial Group:
  1. Cochrane Haematology Group

Copyright:
  1. Copyright © 2012 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.

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Authors

  • Mohamed Kharfan‐Dabaja

    Department of Blood and Marrow Transplantation, H. Lee Moffitt Cancer Center, Division of Oncologic Sciences, University of South Florida, Tampa, USA

    Division of Hematology‐Oncology and Bone Marrow Transplantation Program, American University of Beirut, Beirut, Lebanon

  • Rahul Mhaskar

    Center for Evidence Based Medicine and Health Outcomes Research, University of South Florida, Tampa, USA

  • Tea Reljic

    Center for Evidence Based Medicine and Health Outcomes Research, University of South Florida, Tampa, USA

  • Joseph Pidala

    Department of Blood and Marrow Transplantation, H. Lee Moffitt Cancer Center, Division of Oncologic Sciences, University of South Florida, Tampa, USA

  • Janelle B Perkins

    Department of Blood and Marrow Transplantation, H. Lee Moffitt Cancer Center, Division of Oncologic Sciences, University of South Florida, Tampa, USA

  • Benjamin Djulbegovic

    Department of Blood and Marrow Transplantation, H. Lee Moffitt Cancer Center, Division of Oncologic Sciences, University of South Florida, Tampa, USA

    USF Clinical Translational Science Institute, Dpts of Medicine, Hematology and Health Outcome Research, USF and H. Lee Moffitt Cancer Center, USF Health Clinical Research, University of South Florida, Tampa, USA

  • Ambuj Kumar

    Correspondence to: Center for Evidence Based Medicine and Health Outcomes Research, University of South Florida, Tampa, USA

    [email protected]

    [email protected]

Contributions of authors

MAK‐D, JAP, JBP, BD, and AK contributed to the initiation and design of this review, TR and RM will conduct the search, study selection, and data extraction, MAK‐D, JAP and AK will resolve any disagreements during the conduct of the review, MAK‐D and AK will perform a random data check prior to analysis, TR and RM will perform all analyses, MAK‐D, JAP, JBP, and BD will contribute clinical expertise and BD, RM, and AK will contribute statistical and methodological expertise.

Sources of support

Internal sources

  • None, Not specified.

External sources

  • None, Not specified.

Declarations of interest

The authors do not have any conflicts of interest to report.

Acknowledgements

We would like to thank the Cochrane reviewers and editors for critical reading of our protocol and helpful feedback.

Version history

Published

Title

Stage

Authors

Version

2014 Jul 25

Mycophenolate mofetil versus methotrexate for prevention of graft‐versus‐host disease in people receiving allogeneic hematopoietic stem cell transplantation

Review

Mohamed Kharfan‐Dabaja, Rahul Mhaskar, Tea Reljic, Joseph Pidala, Janelle B Perkins, Benjamin Djulbegovic, Ambuj Kumar

https://doi.org/10.1002/14651858.CD010280.pub2

2012 Dec 12

Mycophenolate mofetil versus methotrexate for prevention of acute graft‐versus‐host disease in patients receiving allogeneic hematopoietic stem cell transplantation

Protocol

Mohamed Kharfan‐Dabaja, Rahul Mhaskar, Tea Reljic, Joseph Pidala, Janelle B Perkins, Benjamin Djulbegovic, Ambuj Kumar

https://doi.org/10.1002/14651858.CD010280

Keywords

MeSH

PICOs

Population
Intervention
Comparison
Outcome

The PICO model is widely used and taught in evidence-based health care as a strategy for formulating questions and search strategies and for characterizing clinical studies or meta-analyses. PICO stands for four different potential components of a clinical question: Patient, Population or Problem; Intervention; Comparison; Outcome.

See more on using PICO in the Cochrane Handbook.