Appendix 1. CENTRAL search strategy

#1 MeSH descriptor Oropharyngeal Neoplasms
#2 MeSH descriptor Head and Neck Neoplasms explode all trees
#3 MeSH descriptor Otorhinolaryngologic Neoplasms explode all trees
#4 MeSH descriptor Neoplasms explode all trees
#5 cancer* OR carcinoma* OR neoplas* OR tumor* OR tumour* OR malignan* OR SCC*
#6 #4 OR #5
#7 MeSH descriptor Oropharynx explode all trees
#8 oropharyn* OR mesopharyn* OR tonsil* OR "head and neck" OR "head neck" OR "head‐neck" OR "head‐and‐neck"
#9 #7 OR #8
#10 #6 AND #9
#11 HNSCC OR SCCHN OR OP‐SCC OR OPSCC
#12 #1 OR #2 OR #3 OR #10 OR #11
#13 MeSH descriptor Tumor Virus Infections explode all trees
#14 MeSH descriptor “Papillomaviridae” explode all trees
#15 MeSH descriptor “Papilloma/virology” explode all trees
#16 hpv* OR papillomavir* OR (papilloma AND vir*)
#17 #13 OR #14 OR #15 OR #16
#18 #12 AND #17
#19 MeSH descriptor Radiotherapy explode all trees
#20 radiotherap* OR radiat* OR irradiat* OR fraction* OR IMRT OR radioimmuno*
#21 MeSH descriptor Oropharyngeal Neoplasms explode all trees with qualifier RT
#22 MeSH descriptor Drug Therapy explode all trees
#23 chemo* OR drug NEXT therap* OR anticarcinogenic OR anti NEXT carcinogenic OR anticancer* OR anti NEXT cancer* OR antineoplastic* OR anti NEXT neoplastic* OR combination AND therap*
#24 MeSH descriptor Oropharyngeal Neoplasms explode all trees with qualifier DT
#25 MeSH descriptor Biological therapy explode all trees
#26 MeSH descriptor Receptor, Epidermal Growth Factor explode all trees with qualifier AI
#27 biotherap* OR biological NEXT therap* OR immunotherap* OR immunisa* OR immuniza* OR immunomodula* OR vaccin* OR ((cell OR gene OR dna OR tissue) AND therap*) OR ((egfr OR (epidermal AND growth AND factor AND receptor*) AND inhibit*))
#28 #19 OR #20 OR #21 OR #22 OR #23 OR #24 OR #25 OR #26 OR #27
#29 #18 AND #28