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Transarterial (chemo)embolisation for liver metastases

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Appendices

Appendix 1. Search Strategy

Database

Time span

Search strategy

The Cochrane Hepato‐Biliary Group Controlled Trials Register

Date will be given at review status.

(((liver or hepatic or hepatocellular* or hepato‐cellular*) AND (cancer* or neoplasm* or
malign* or carcinoma* or tumo*)) OR ((metasta* or secondar* or spread or advanced)
AND (liver or hepatic))) and (Ablati* OR (injection* and (ethanol or acetic acid)) or PEI or PAI)

Cochrane Central Register of Controlled Trials (CENTRAL) in The Cochrane Library

Latest issue.

(((liver or hepatic or hepatocellular* or hepato‐cellular*) AND (cancer* or neoplasm* or
malign* or carcinoma* or tumo*)) OR ((metasta* or secondar* or spread or advanced)
AND (liver or hepatic))) and (rfta or radio‐frequ* or radiofrequ* or rfa or rf OR Ablati*
OR (injection* and (ethanol or acetic acid)) or PEI or PAI OR Yttrium Radioisotopes OR
selective internal radi* OR radioemboli* OR radio‐emboli* OR sir‐sphere* OR
therasphere* OR ((yttrium* or 90y* or radiolabel*) AND microsphere*) OR Embolisation
OR Embolisation OR ((transcatheter or transarterial) and (emboli* or chemoemboli*)) or TAE or TACE or lipiodolisation or lipiodol embolisation OR lipiodol or HAI or arterial
infusion or targeted chemotherapy OR ((transcatheter or transarterial) and chemoinfusion) OR Iodized Oil OR thermotherapy OR Hyperthermia OR Microwaves or
coagulation OR cryosurgery)

MEDLINE (Ovid SP)

1950 to the date of search.

1 exp Carcinoma, Hepatocellular/
2 exp Liver Neoplasms/
3 hcc.mp.
4 ((liver or hepatic or hepatocellular$ or hepato‐cellular$) adj5 (cancer$ or neoplas$ or malign$ or carcinom$ or tumo$)).mp.
5 1 or 2 or 3 or 4
6 exp Neoplasm Metastasis/
7 (metasta* or secondar* or spread or advanced).mp.
8 6 or 7
9 exp Neuroendocrine Tumors/
10 exp Apudoma/
11 exp Carcinoid Tumour/
12 exp Adenoma, Islet Cell/
13 exp Insulinoma/
14 exp Carcinoma, Islet Cell/
15 exp Gastrinoma/
16 exp Glucagonoma/
17 exp Somatostatinoma/
18 exp Vipoma/
19 exp Multiple Endocrine Neoplasia/
20 exp Pancreatic Neoplasms/
21 exp Malignant Carcinoid Syndrome/
22 (neuroendocrine tumour or neuroendocrine tumours or neuroendocrine tumour or neuroendocrine tumours or adenoma or adenomas or apudoma or apudomas or carcinoid or carcinoids).mp.
23 (argentaffinoma or argentaffinomas or somatostatinoma or somatostatinomas or islet cell tumour or islet cell tumours or island cell tumour or island cell tumours or nesidioblastoma).mp.
24 (nesidioblastomas or insulinoma or insulinomas or multiple endocrine neoplasia or multiple endocrine adenopathy or multiple endocrine adenopathies or multiple endocrine adenomatoses).mp.
25 (multiple endocrine adenomatosis or familial endocrine adenomatoses or familial endocrine adenomatosis or multiple endocrine neoplasms or vipoma or vipomas or diarrheogenic tumour).mp.
26 (diarrheogenic tumours or diarrheogenic tumour or diarrheogenic tumours or VIP secreting tumour or VIP secreting tumours or VIP secreting tumour or VIP secreting tumours).mp.
27 (Pancreatic cholera or Verner‐Morrison syndrome or Verner Morrison syndrome or watery diarrhoea syndrome or watery diarrhoea syndrome or WDHA or WDHH or neuroendocrine carcinoma or neuroendocrine carcinomas or carcinoid syndrome).mp.
28 9 or 10 or 11 or 12 or 13 or 14 or 15 or 16 or 17 or 18 or 19 or 20 or 21 or 22 or 23 or 24 or 25 or 26 or 27
29 exp Colorectal Neoplasms/
30 ((colon$ or rect$ or colorect$ or bowel or large intestin$) adj5 neoplas$).tw,mp.
31 ((colon$ or rect$ or colorect$ or bowel or large intestin$) adj5 cancer$).tw,mp.
32 ((colon$ or rect$ or colorect$ or bowel or large intestin$) adj5 carcinoma$).tw,mp.
33 ((colon$ or rect$ or colorect$ or bowel or large intestin$) adj5 tumo$).tw,mp.
34 ((colon$ or rect$ or colorect$ or bowel or large intestin$) adj5 malignan$).tw,mp.
35 ((colon$ or rect$ or colorect$ or bowel or large intestin$) adj5 adenocarcinoma$).tw,mp.
36 29 or 30 or 31 or 32 or 33 or 34 or 35
37 exp Liver/
38 (liver or hepatic).mp.
39 37 or 38
40 28 or 36
41 8 and 39 and 40
42 5 or 41
43 randomised controlled trial.pt.
44 controlled clinical trial.pt.
45 randomized.ab.
46 placebo.ab.
47 randomly.ab.
48 trial.ab.
49 groups.ab.
50 43 or 44 or 45 or 46 or 47 or 48 or 49
51 humans.sh.
52 50 and 51
53 (rfta or radio‐frequ$ or radiofrequ$ or rfa or rf).mp.
54 exp Catheter Ablation/
55 53 or 54
56 percutaneous.mp.
57 (ablati* and (therap* or treatment* or radiofrequenc* or cryo*)).mp.
58 ((injection* and (ethanol or acetic acid)) or PEI or PAI).mp.
59 57 or 58
60 56 and 59
61 exp Yttrium Radioisotopes/
62 selective internal radi$.tw,mp.
63 radioemboli$.tw,mp.
64 radio‐emboli$.tw,mp.
65 sir‐sphere$.tw,mp.
66 therasphere$.tw,mp.
67 ((yttrium$ or $yttrium or 90y$ or radiolabel$) adj5 microsphere$).tw,mp.
68 61 or 62 or 63 or 64 or 65 or 66 or 67
69 exp Chemoembolisation, Therapeutic/
70 exp Embolisation, Therapeutic/
71 (((transcatheter or transarterial) and (emboli* or chemoemboli*)) or TAE or TACE or lipiodolisation or lipiodol embolisation).mp.
72 exp Infusions, Intra‐Arterial/
73 (lipiodol or HAI or arterial infusion or targeted chemotherapy).mp.
74 ((transcatheter or transarterial) and chemo‐infusion).mp.
75 exp Iodized Oil/
76 69 or 70 or 71 or 72 or 73 or 74 or 75
77 thermotherapy.mp. or exp Hyperthermia, Induced/
78 exp Microwaves/ or coagulation therapy.mp. or exp Electrocoagulation/
79 exp Catheter Ablation/ or ablation.mp.
80 cryosurgery.mp. or exp Cryosurgery/
81 55 or 60 or 68 or 76 or 77 or 78 or 79 or 80
82 42 and 52 and 81

EMBASE (Ovid SP)

1974 to the date of search.

1 Liver‐Cell‐Carcinoma#
2 Liver‐Tumour#
3 hcc AND CLINICAL‐TRIAL# AND HUMAN=YES
4 (liver OR hepatic OR hepatocellular$3 OR hepato‐cellular$3) NEAR (cancer$3 OR neoplas$3 OR malign$5 OR carcinom$3 OR tumo$3) AND CLINICAL‐TRIAL# AND HUMAN=YES
5 1 OR 2 OR 3 OR 4
6 Metastasis#
7 metasta$5 OR secondar$3 OR spread OR advanced
8 6 OR 7
9 Neuroendocrine‐Tumour#
10 Apudoma#
11 Carcinoid#
12 Pancreas‐Islet‐Cell‐Tumour#
13 Insulinoma#
14 Pancreas‐Islet‐Cell‐Carcinoma#
15 Gastrinoma#
16 Glucagonoma#
17 Somatostatinoma#
18 Vipoma#
19 Multiple‐Endocrine‐Neoplasia#
20 Pancreas‐Tumour#
21 Carcinoid‐Syndrome#
22 neuroendocrine ADJ tumour OR neuroendocrine ADJ tumours OR neuroendocrine ADJ tumour OR neuroendocrine ADJ tumours OR adenoma OR adenomas OR apudoma OR apudomas OR carcinoid OR carcinoids
23 argentaffinoma OR argentaffinomas OR somatostatinoma OR somatostatinomas OR islet ADJ cell ADJ tumour OR islet ADJ cell ADJ tumours OR island ADJ cell ADJ tumour OR island ADJ cell ADJ tumours OR nesidioblastoma
24 multiple ADJ endocrine ADJ adenomatosis OR familial ADJ endocrine ADJ adenomatoses OR familial ADJ endocrine ADJ adenomatosis OR multiple ADJ endocrine ADJ neoplasms OR vipoma OR vipomas OR diarrheogenic ADJ tumour
25 nesidioblastomas OR insulinoma OR insulinomas OR multiple ADJ endocrine ADJ neoplasia OR multiple ADJ endocrine ADJ adenopathy OR multiple ADJ endocrine ADJ adenopathies OR multiple ADJ endocrine ADJ adenomatoses
26 diarrheogenic ADJ tumours OR diarrheogenic ADJ tumour OR diarrheogenic ADJ tumours OR VIP ADJ secreting ADJ tumour OR VIP ADJ secreting ADJ tumours OR VIP ADJ secreting ADJ tumour OR VIP ADJ secreting ADJ tumours
27 Pancreatic ADJ cholera OR Verner‐Morrison ADJ syndrome OR Verner ADJ Morrison ADJ syndrome OR watery ADJ diarrhoea ADJ syndrome OR watery ADJ diarrhoea ADJ syndrome OR WDHA OR WDHH OR neuroendocrine ADJ carcinoma OR neuroendocrine ADJ carcinomas OR carcinoid ADJ syndrome
28 9 OR 10 OR 11 OR 12 OR 13 OR 14 OR 15 OR 16 OR 17 OR 18 OR 19 OR 20 OR 21 OR 22 OR 23 OR 24 OR 25 OR 26 OR 27
29 Colorectal‐Tumour#
30 (colon$5 OR rect$5 OR colorect$3 OR bowel OR large ADJ intestin$5) NEAR neoplas$5
31 (colon$5 OR rect$5 OR colorect$3 OR bowel OR large ADJ intestin$5) NEAR cancer$3
32 (colon$5 OR rect$5 OR colorect$3 OR bowel OR large ADJ intestin$5) NEAR carcinoma$5
33 (colon$5 OR rect$5 OR colorect$3 OR bowel OR large ADJ intestin$5) NEAR tumo$5
34 (colon$5 OR rect$5 OR colorect$3 OR bowel OR large ADJ intestin$5) NEAR malignan$5
35 (colon$5 OR rect$5 OR colorect$3 OR bowel OR large ADJ intestin$5) NEAR adenocarcinoma$5
36 29 OR 30 OR 31 OR 32 OR 33 OR 34 OR 35
37 Liver#
38 liver OR hepatic
39 37 OR 38
40 28 OR 36
41 8 AND 39 AND 40
42 5 OR 41
43 random$7 OR factorial$3 OR crossover$3 OR cross ADJ over$3 OR placebo$3 OR doubl$3 ADJ blind$5 OR singl$3 ADJ blind$5 OR assign$7 OR allocat$5 OR volunteer$3
44 Crossover‐Procedure#
45 Double‐Blind‐Procedure#
46 Randomized‐Controlled‐Trial#
47 Single‐Blind‐Procedure#
48 43 OR 44 OR 45 OR 46 OR 47
49 rfta OR radio‐frequ$7 OR radiofrequ$7 OR rfa OR rf
50 Catheter‐Ablation#
51 49 OR 50
52 percutaneous
53 ablati$5 AND (therap$5 OR treatment$3 OR radiofrequenc$3 OR cryo$7)
54 injection$3 AND (ethanol OR acetic ADJ acid) OR PEI OR PAI
55 53 OR 54
56 52 AND 55
57 Yttrium#
58 selective ADJ internal ADJ radi$7 OR radioemboli$7 OR radio‐emboli$7 OR sir‐sphere$5 OR therasphere$5
59 (yttrium$7 OR 90y$7 OR radiolabel$7) NEAR microsphere$3
60 57 OR 58 OR 59
61 Chemoembolisation#
62 Artificial‐Embolism#
63 (transcatheter OR transarterial) AND (emboli$5 OR chemoemboli$5) OR TAE OR TACE OR lipiodolisation OR lipiodol ADJ embolisation
64 Intraarterial‐Drug‐Administration#.DE.
65 lipiodol OR HAI OR arterial ADJ infusion OR targeted ADJ chemotherapy
66 (transcatheter OR transarterial) AND chemo‐infusion
67 (transcatheter OR transarterial) AND chemo ADJ infusion
68 Iodinated‐Poppyseed‐Oil#.DE.
69 61 OR 62 OR 63 OR 64 OR 65 OR 66 OR 67 OR 68
70 Hyperthermic‐Therapy
71 thermotherapy
72 Microwave‐Radiation#
73 Cryocoagulation# OR Electrocoagulation# OR Laser‐Coagulation#
74 coagulation ADJ therapy
75 Catheter‐Ablation#
76 ablation
77 Cryosurgery#.W..DE.
78 70 OR 71 OR 72 OR 73 OR 74 OR 75 OR 76 OR 77
79 51 OR 56 OR 60 OR 69 OR 78
80 42 AND 48 AND 79
81 HUMAN=YES
82 80 AND 81
83 CLINICAL‐TRIAL#
84 82 AND 83

Science Citation Index Expanded (http://apps.isiknowledge.com)

1970 to the date of search.

# 70 #69 AND #37 AND #30
# 69 #68 OR #67 OR #66 OR #65 OR #64 OR #54 OR #45 OR #40
# 68 TS=(cryosurgery OR cryo‐surgery)
# 67 TS=(ablation*)
# 66 TS=(Microwaves* or Microwave‐Radiation* OR coagulation therapy or Electrocoagulation* or Electro‐coagulation* or Cryocoagulation* OR Laser‐Coagulation* OR Cryo‐coagulation* )
# 65 TS= (thermotherapy or Induced Hyperthermia or Hyperthermic Therapy)
# 64 #63 OR #62 OR #61 OR #60 OR #59 OR #58 OR #57 OR #56 OR #55
# 63 TS=Iodinated Poppyseed Oil
# 62 TS=Intra‐arterial Drug Administration
# 61 TS=Artificial‐Embolism
# 60 TS=Iodized Oil*
# 59 TS=((transcatheter or transarterial) and chemo‐infusion)
# 58 TS=(lipiodol or HAI or arterial infusion or targeted chemotherapy)
# 57 TS=Intra‐Arterial Infusion*
# 56 TS=(((transcatheter or transarterial) and (emboli* or chemoemboli*)) or TAE or TACE or lipiodolisation or lipiodol embolisation)
# 55 TS=Embolisation
# 54 #53 OR #52 OR #51 OR #50 OR #49 OR #48 OR #47 OR #46
# 53 TS=Yttrium
# 52 TS=((yttrium* and microsphere*) or (90y* and microsphere*) or (radiolabel* and microsphere*))
# 51 TS=therasphere*
# 50 TS=sir‐sphere*
# 49 TS=radio‐emboli*
# 48 TS=radioemboli*
# 47 TS=selective internal radi*
# 46 TS=Yttrium Radioisotopes
# 45 #44 AND #41
# 44 #43 OR #42
# 43 TS=((injection* and (ethanol or acetic acid)) or PEI or PAI)
# 42 TS=(ablati* and (therap* or treatment* or radiofrequenc* or cryo*))
# 41 TS=percutaneous
# 40 #39 OR #38
# 39 TS=Catheter Ablation
# 38 TS=(rfta or radio‐frequ* or radiofrequ* or rfa or rf)
# 37 #36 AND #35
# 36 TS=human*
# 35 #34 OR #33 OR #32 OR #31
# 34 TS=trial*
# 33 TS=random*
# 32 TS=groups
# 31 TS=placebo
# 30 #29 OR #10
# 29 #28 AND #27 AND #11
# 28 #26 OR #19
# 27 TS=(liver or hepatic)
# 26 #25 OR #24 OR #23 OR #22 OR #21 OR #20
# 25 TS=(colon* adenocarcinoma* or rect* adenocarcinoma* or colorect* adenocarcinoma* or bowel adenocarcinoma* or large intestin* adenocarcinoma*)
# 24 TS=(colon* malignan* or rect* malignan* or colorect* malignan* or bowel malignan* or large intestin* malignan*)
# 23 TS=(colon* tumo* or rect* tumo* or colorect* tumo* or bowel tumo* or large intestin* tumo*)
# 22 TS=(colon* carcinoma* or rect* carcinoma* or colorect* carcinoma* or bowel carcinoma* or large intestin* carcinoma*)
# 21 TS=(colon* cancer* or rect* cancer* or colorect* cancer* or bowel cancer* or large intestin* cancer*)
# 20 TS=(colon* neoplas* or rect* neoplas* or colorect* neoplas* or bowel neoplas* or large intestin* neoplas*)
# 19 #18 OR #17 OR #16 OR #15 OR #14 OR #13 OR #12
# 18 TS=(Gastrinoma or Glucagonoma or Somatostatinoma or Pancreatic Neoplasm*)
# 17 TS=(Pancreatic cholera or Verner‐Morrison syndrome or Verner Morrison syndrome or watery diarrhoea syndrome or watery diarrhoea syndrome or WDHA or WDHH or neuroendocrine carcinoma or neuroendocrine carcinomas or carcinoid syndrome)
# 16 TS=(diarrheogenic tumours or diarrheogenic tumour or diarrheogenic tumours or VIP secreting tumour or VIP secreting tumours or VIP secreting tumour or VIP secreting tumours)
# 15 TS=(multiple endocrine adenomatosis or familial endocrine adenomatoses or familial endocrine adenomatosis or multiple endocrine neoplasms or vipoma or vipomas or diarrheogenic tumour)
# 14 TS=(nesidioblastomas or insulinoma or insulinomas or multiple endocrine neoplasia or multiple endocrine adenopathy or multiple endocrine adenopathies or multiple endocrine adenomatoses)
# 13 TS=(argentaffinoma or argentaffinomas or somatostatinoma or somatostatinomas or islet cell tumour or islet cell tumours or island cell tumour or island cell tumours or nesidioblastoma)
# 12 TS=(neuroendocrine tumour or neuroendocrine tumours or neuroendocrine tumour or neuroendocrine tumours or adenoma or adenomas or apudoma or apudomas or carcinoid or carcinoids)
# 11 TS=(Neoplasm Metastasis or metasta* or secondar* or spread or advanced)
# 10 #9 OR #8 OR #7 OR #6 OR #5 OR #4 OR #3 OR #2 OR #1
# 9 TS=(Liver‐Cell‐Carcinoma or Liver Cell Carcinoma)
# 8 TS=(liver malign* or hepatic malign* or hepatocellular* malign* or hepato‐cellular* malign*)
# 7 TS=(liver tumo* or hepatic tumo* or hepatocellular* tumo* or hepato‐cellular* tumo*)
# 6 TS=(liver carcinom* or hepatic carcinom* or hepatocellular* carcinom* or hepato‐cellular* carcinom*)
# 5 TS=(liver neoplas* or hepatic neoplas* or hepatocellular* neoplas* or hepato‐cellular* neoplas*)
# 4 TS=(liver cancer* or hepatic cancer* or hepatocellular* cancer* or hepato‐cellular* cancer*)
# 3 TS=hcc
# 2 TS=Liver Neoplasms
# 1 TS=Hepatocellular Carcinoma

LILACS

Latest issue.

(Pt RANDOMIZED CONTROLLED TRIAL OR Pt CONTROLLED CLINICAL TRIAL
OR Mh RANDOMIZED CONTROLLED TRIALS OR Mh RANDOM ALLOCATION
OR Mh DOUBLE‐BLIND METHOD OR Mh SINGLE‐BLIND METHOD OR Pt
MULTICENTER STUDY) OR ((tw ensaio or tw ensayo or tw trial) and (tw azar or tw
acaso or tw placebo or tw control$ or tw aleat$ or tw random$ or (tw duplo and tw cego)
or (tw doble and tw ciego) or (tw double and tw blind)) and tw clinic$)) AND NOT ((CT
ANIMALS OR MH ANIMALS OR CT RABBITS OR CT MICE OR MH RATS OR
MH PRIMATES OR MH DOGS OR MH RABBITS OR MH SWINE) AND NOT (CT
HUMAN AND CT ANIMALS)) [Palavras] and (liver or hepatic) [Palavras]

CINAHL

1982 to the date of search.

1 exp Carcinoma, Hepatocellular/
2 exp Liver Neoplasms/
3 hcc.mp.
4 ((liver or hepatic or hepatocellular$ or hepato‐cellular$) adj5 (cancer$ or neoplas$ or malign$ or carcinom$ or tumo$)).mp.
5 1 or 2 or 3 or 4
6 exp Neoplasm Metastasis/
7 (metasta* or secondar* or spread or advanced).mp.
8 6 or 7
9 exp Neuroendocrine Tumors/
10 Apudoma.mp.
11 exp Carcinoid Tumour/
12 exp Adenoma, Islet Cell/
13 exp INSULINOMA/
14 exp Carcinoma, Islet Cell/
15 exp GASTRINOMA/
16 Glucagonoma.mp. or exp Glucagon/
17 Somatostatinoma.mp.
18 Vipoma.mp.
19 exp Endocrine Gland Neoplasms/ or Multiple Endocrine Neoplasia.mp.
20 exp Pancreatic Neoplasms/
21 Malignant Carcinoid Syndrome.mp. or exp Gastrointestinal Neoplasms/
22 (neuroendocrine tumour or neuroendocrine tumours or neuroendocrine tumour or neuroendocrine tumours or adenoma or adenomas or apudoma or apudomas or carcinoid or carcinoids).mp.
23 (argentaffinoma or argentaffinomas or somatostatinoma or somatostatinomas or islet cell tumour or islet cell tumours or island cell tumour or island cell tumours or nesidioblastoma).mp.
24 (nesidioblastomas or insulinoma or insulinomas or multiple endocrine neoplasia or multiple endocrine adenopathy or multiple endocrine adenopathies or multiple endocrine adenomatoses).mp.
25 (multiple endocrine adenomatosis or familial endocrine adenomatoses or familial endocrine adenomatosis or multiple endocrine neoplasms or vipoma or vipomas or diarrheogenic tumour).mp.
26 (diarrheogenic tumours or diarrheogenic tumour or diarrheogenic tumours or VIP secreting tumour or VIP secreting tumours or VIP secreting tumour or VIP secreting tumours).mp.
27 (Pancreatic cholera or Verner‐Morrison syndrome or Verner Morrison syndrome or watery diarrhoea syndrome or watery diarrhoea syndrome or WDHA or WDHH or neuroendocrine carcinoma or neuroendocrine carcinomas or carcinoid syndrome).mp.
28 9 or 10 or 11 or 12 or 13 or 14 or 15 or 16 or 17 or 18 or 19 or 20 or 21 or 22 or 23 or 24 or 25 or 26 or 27
29 exp Colorectal Neoplasms/
30 ((colon$ or rect$ or colorect$ or bowel or large intestin$) adj5 neoplas$).tw,mp.
31 ((colon$ or rect$ or colorect$ or bowel or large intestin$) adj5 cancer$).tw,mp.
32 ((colon$ or rect$ or colorect$ or bowel or large intestin$) adj5 carcinoma$).tw,mp.
33 ((colon$ or rect$ or colorect$ or bowel or large intestin$) adj5 tumo$).tw,mp.
34 ((colon$ or rect$ or colorect$ or bowel or large intestin$) adj5 malignan$).tw,mp.
35 ((colon$ or rect$ or colorect$ or bowel or large intestin$) adj5 adenocarcinoma$).tw,mp.
36 29 or 30 or 31 or 32 or 33 or 34 or 35
37 exp LIVER/
38 (liver or hepatic).mp.
39 37 or 38
40 28 or 36
41 8 and 39 and 40
42 5 or 41
43 randomised controlled trial.pt.
44 controlled clinical trial.pt.
45 randomized.ab.
46 placebo.ab.
47 randomly.ab.
48 trial.ab.
49 groups.ab.
50 43 or 44 or 45 or 46 or 47 or 48 or 49
51 (rfta or radio‐frequ$ or radiofrequ$ or rfa or rf).mp.
52 exp Catheter Ablation/
53 51 or 52
54 percutaneous.mp.
55 (ablati* and (therap* or treatment* or radiofrequenc* or cryo*)).mp.
56 ((injection* and (ethanol or acetic acid)) or PEI or PAI).mp.
57 55 or 56
58 54 and 57
59 Yttrium Radioisotopes.mp.
60 selective internal radi$.tw,mp.
61 radioemboli$.tw,mp.
62 radio‐emboli$.tw,mp.
63 sir‐sphere$.tw,mp.
64 therasphere$.tw,mp.
65 ((yttrium$ or $yttrium or 90y$ or radiolabel$) adj5 microsphere$).tw,mp.
66 59 or 60 or 61 or 62 or 63 or 64 or 65
67 exp Chemoembolisation, Therapeutic/
68 exp Embolisation, Therapeutic/
69 (((transcatheter or transarterial) and (emboli* or chemoemboli*)) or TAE or TACE or lipiodolisation or lipiodol embolisation).mp.
70 exp Infusions, Intraarterial/
71 (lipiodol or HAI or arterial infusion or targeted chemotherapy).mp.
72 ((transcatheter or transarterial) and chemo‐infusion).mp.
73 Iodized Oil.mp.
74 67 or 68 or 69 or 70 or 71 or 72 or 73
75 exp Hyperthermia, Induced/
76 thermotherapy.mp.
77 exp MICROWAVES/
78 Electrocoagulation.mp.
79 coagulation therapy.mp.
80 exp Catheter Ablation/
81 ablation.mp.
82 cryosurgery.mp. or exp CRYOSURGERY/
83 53 or 58 or 66 or 74 or 75 or 76 or 77 or 78 or 79 or 80 or 81 or 82
84 42 and 52 and 83