Appendix 1. Search strategy

MEDLINE (Ovid) search strategy

1. exp Burns/
2. burn*.ab,ti.
3. (thermal adj3 injur*).ab,ti.
4. 1 or 2 or 3
5. exp Heparin/
6. (Heparin or UFH or LMWH or liquaemin or heparan or keratin or dermatan or chondroitin or hyaluronic acid).ab,ti.
7. 5 or 6
8. 4 and 7
9. randomi?ed.ab,ti.
10. randomized controlled trial.pt.
11. controlled clinical trial.pt.
12. placebo.ab.
13. clinical trials as topic.sh.
14. randomly.ab.
15. trial.ti.
16. 9 or 10 or 11 or 12 or 13 or 14 or 15
17. (animals not (humans and animals)).sh.
18. 16 not 17
19. 8 and 18

Chinese databases search strategy

We will search Chinese databases (ie CBM, CNKI, VIP database, Wanfang database, and ChiCTR) in Chinese using a translation of the following key words:

1. burns

2. thermal injury

3. heparin or liquaemin or heparan or keratin or dermatan or chondroitin or hyaluronic acid

4. 1 and 2 and 3