Appendix 1. Appendix: Medline Search Strategy

1. cerebrovascular disorders/ or exp basal ganglia cerebrovascular disease/ or exp brain ischemia/ or exp carotid artery diseases/ or exp intracranial arterial diseases/ or exp "intracranial embolism and thrombosis"/ or exp intracranial hemorrhages/ or stroke/ or exp brain infarction/ or vasospasm, intracranial/ or vertebral artery dissection/
2. (stroke or poststroke or post‐stroke or cerebrovasc$ or brain vasc$ or cerebral vasc$ or cva$ or apoplex$ or SAH).tw.
3. ((brain$ or cerebr$ or cerebell$ or intracran$ or intracerebral) adj5 (isch?emi$ or infarct$ or thrombo$ or emboli$ or occlus$)).tw.
4. ((brain$ or cerebr$ or cerebell$ or intracerebral or intracranial or subarachnoid) adj5 (haemorrhage$ or hemorrhage$ or haematoma$ or hematoma$ or bleed$)).tw.
5. hemiplegia/ or exp paresis/
6. (hemipleg$ or hemipar$ or paresis or paretic).tw.
7. brain injuries/ or brain injury, chronic/
8. or/1‐7
9. anxiety/
10. anxiety disorders/ or agoraphobia/ or obsessive‐compulsive disorder/ or panic disorder/ or phobic disorders/ or exp stress disorders, traumatic/
11. exp Anti‐Anxiety Agents/
12. (anxiety or anxieties or anxious or agoraphobi$ or phobi$ or panic disorder$ or panic attack$ or (obsess$ adj3 compuls$) or post?traumatic stress$ or PTSD).tw.
13. (feel$ adj5 (apprehens$ or dread or disaster$ or fear$ or worry or worried or terror)).tw.
14. manifest anxiety scale/
15. or/9‐14
16. 8 and 15
17. Randomized Controlled Trials as Topic/
18. random allocation/
19. Controlled Clinical Trials as Topic/
20. control groups/
21. clinical trials as topic/ or clinical trials, phase i as topic/ or clinical trials, phase ii as topic/ or clinical trials, phase iii as topic/ or clinical trials, phase iv as topic/
22. double‐blind method/
23. single‐blind method/
24. Placebos/
25. placebo effect/
26. cross‐over studies/
27. Multicenter Studies as Topic/
28. Therapies, Investigational/
29. Drug Evaluation/
30. Research Design/
31. Program Evaluation/
32. evaluation studies as topic/
33. randomized controlled trial.pt.
34. controlled clinical trial.pt.
35. (clinical trial or clinical trial phase i or clinical trial phase ii or clinical trial phase iii or clinical trial phase iv).pt.
36. multicenter study.pt.
37. (evaluation studies or comparative study).pt.
38. random$.tw.
39. (controlled adj5 (trial$ or stud$)).tw.
40. (clinical$ adj5 trial$).tw.
41. ((control or treatment or experiment$ or intervention) adj5 (group$ or subject$ or patient$)).tw.
42. (quasi‐random$ or quasi random$ or pseudo‐random$ or pseudo random$).tw.
43. ((multicenter or multicentre or therapeutic) adj5 (trial$ or stud$)).tw.
44. ((control or experiment$ or conservative) adj5 (treatment or therapy or procedure or manage$)).tw.
45. ((singl$ or doubl$ or tripl$ or trebl$) adj5 (blind$ or mask$)).tw.
46. (coin adj5 (flip or flipped or toss$)).tw.
47. (cross‐over or cross over or crossover).tw.
48. placebo$.tw.
49. sham.tw.
50. (assign$ or alternate or allocat$ or counterbalance$ or multiple baseline).tw.
51. controls.tw.
52. (treatment$ adj6 order).tw.
53. or/17‐52
54. 16 and 53
55. limit 54 to humans