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Cochrane Database of Systematic Reviews

Nitric oxide donors for cervical ripening in first‐trimester surgical abortion

This is not the most recent version

view the current version 25 February 2015

Information

DOI:
https://doi.org/10.1002/14651858.CD007444.pub2Copy DOI
Database:
  1. Cochrane Database of Systematic Reviews
Version published:
  1. 07 October 2009see what's new
Type:
  1. Intervention
Stage:
  1. Review
Cochrane Editorial Group:

  1. Cochrane Fertility Regulation Group

Copyright:
  1. Copyright © 2010 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.

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Authors

Contributions of authors

P Promsonthi wrote the protocol and the review. B Chanrachakul initiated the idea for the review and supervised P Promsonthi. D Preechapornprasert involved in selecting trials for inclusion. All review authors approved the final version of the protocol and the review.

Sources of support

Internal sources

  • None, Not specified.

External sources

  • None, Not specified.

Declarations of interest

None known.

Acknowledgements

‐

Version history

Published

Title

Stage

Authors

Version

2015 Feb 25

Nitric oxide donors for cervical ripening in first‐trimester surgical abortion

Review

Patama Promsonthi, Anyarin Preechapornprasert, Boonsri Chanrachakul

https://doi.org/10.1002/14651858.CD007444.pub4

2011 Dec 07

Nitric oxide donors for cervical ripening in first‐trimester surgical abortion

Review

Patama Promsonthi, Domerudee Preechapornprasert, Boonsri Chanrachakul

https://doi.org/10.1002/14651858.CD007444.pub3

2009 Oct 07

Nitric oxide donors for cervical ripening in first‐trimester surgical abortion

Review

Patama Promsonthi, Domerudee Preechapornprasert, Boonsri Chanrachakul

https://doi.org/10.1002/14651858.CD007444.pub2

2009 Jul 08

Nitric oxide donors for cervical ripening in first trimester for termination of pregnancy

Protocol

Patama Promsonthi, Domerudee Preechapornprasert, Boonsri Chanrachakul

https://doi.org/10.1002/14651858.CD007444

Differences between protocol and review

Protocol: Nitric oxide donors for cervical ripening in first trimester for termination of pregnancy

Planned to analyse

Primary outcomes

(1) Complete abortion as defined by complete evacuation of fetal and placental material from the uterus.

(2) Complications (post‐abortion infection requiring antibiotic treatment, need for blood transfusion, any complication requiring unintended surgery, cervical injury, uterine perforation, maternal death or serious maternal morbidity).

(3) Cervical changes: dilatation, length and cervical resistance.

Secondary outcomes

(1) Pain requiring analgesic drugs.

(2) Side effects of drugs and treatment.

(3) Hospital stay.

(4) Patient satisfaction.

Review: Nitric oxide donors for cervical ripening in first trimester surgical abortion

Primary outcome: complications, cervical changes

Secondary outcomes: Side effects of drugs, patient satisfaction

PICOs

Population
Intervention
Comparison
Outcome

The PICO model is widely used and taught in evidence-based health care as a strategy for formulating questions and search strategies and for characterizing clinical studies or meta-analyses. PICO stands for four different potential components of a clinical question: Patient, Population or Problem; Intervention; Comparison; Outcome.

See more on using PICO in the Cochrane Handbook.