Scolaris Content Display Scolaris Content Display

Cochrane Database of Systematic Reviews

Doxycycline for osteoarthritis of the knee or hip

This is not the most recent version

Information

DOI:
https://doi.org/10.1002/14651858.CD007323.pub2Copy DOI
Database:
  1. Cochrane Database of Systematic Reviews
Version published:
  1. 07 October 2009see what's new
Type:
  1. Intervention
Stage:
  1. Review
Cochrane Editorial Group:
  1. Cochrane Musculoskeletal Group

Copyright:
  1. Copyright © 2010 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.

Article metrics

Altmetric:

Cited by:

Cited 0 times via Crossref Cited-by Linking

Collapse

Authors

  • Eveline Nüesch

    Correspondence to: Division of Clinical Epidemiology and Biostatistics, Institute of Social and Preventive Medicine, University of Bern, Bern, Switzerland

    [email protected]

  • Anne WS Rutjes

    Division of Clinical Epidemiology and Biostatistics, Institute of Social and Preventive Medicine, University of Bern, Bern, Switzerland

  • Sven Trelle

    Institute of Social and Preventive Medicine, University of Bern, Bern, Switzerland

  • Stephan Reichenbach

    Department for Rheumatology, Clinical Immunology, and Allergology, University Hospital, Bern, Switzerland

  • Peter Jüni

    Division of Clinical Epidemiology and Biostatistics, Institute of Social and Preventive Medicine, University of Bern, Bern, Switzerland

Contributions of authors

Protocol completion: Nüesch, Rutjes, Trelle, Reichenbach, Jüni
Acquisition of data: Nüesch, Rutjes
Analysis and interpretation of data: Nüesch, Rutjes, Trelle, Reichenbach, Jüni
Manuscript preparation: Nüesch, Rutjes, Trelle, Reichenbach, Jüni
Statistical analysis. Nüesch, Rutjes

Sources of support

Internal sources

  • Institute of Social and Preventive Medicine, University or Bern, Switzerland.

    Intramural grants

External sources

  • Swiss National Science Foundation, Switzerland.

    National Research Program 53 on musculoskeletal health (grant numbers 4053‐40‐104762/3 and 3200‐066378)

Declarations of interest

None.

Acknowledgements

We thank the Cochrane Musculoskeletal Group editorial team for valuable comments and Malcolm Sturdy for database support. The authors are grateful to Kenneth Brandt and Steve Mazzuca for providing unpublished data from their trial.

Version history

Published

Title

Stage

Authors

Version

2012 Nov 14

Doxycycline for osteoarthritis of the knee or hip

Review

Bruno R da Costa, Eveline Nüesch, Stephan Reichenbach, Peter Jüni, Anne WS Rutjes

https://doi.org/10.1002/14651858.CD007323.pub3

2009 Oct 07

Doxycycline for osteoarthritis of the knee or hip

Review

Eveline Nüesch, Anne WS Rutjes, Sven Trelle, Stephan Reichenbach, Peter Jüni

https://doi.org/10.1002/14651858.CD007323.pub2

2009 Jul 08

Doxycycline for osteoarthritis of the knee or hip

Protocol

Eveline Nüesch, Anne WS Rutjes, Sven Trelle, Stephan Reichenbach, Peter Jüni

https://doi.org/10.1002/14651858.CD007323

Differences between protocol and review

Because only one study was included in our review, we used inverse variance fixed‐effect model instead of the random‐effects model of meta‐analysis, and we did not perform the stratified analyses. Differences between experimental and control groups were expressed as mean differences instead of standardised mean differences due to better interpretability of the results. We could not perform stratified analyses or funnel plot evaluation to investigate whether potential variation between trials could be explained by biases affecting individual trials or by publication bias.