Antiretroviral resistance testing in people living with HIV
Appendices
Appendix 1. CENTRAL search strategy
| ID | Search |
| #1 | MeSH descriptor: [HIV Infections] explode all trees |
| #2 | MeSH descriptor: [HIV] explode all trees |
| #3 | hiv or hiv‐1* or hiv‐2* or hiv1 or hiv2 or (hiv near infect*) or (human immunodeficiency virus) or (human immunedeficiency virus) or (human immune‐deficiency virus) or (human immuno‐deficiency virus) or (human immune deficiency virus) or (human immuno deficiency virus) or (acquired immunodeficiency syndrome) or (acquired immunedeficiency syndrome) or (acquired immuno‐deficiency syndrome) or (acquired immune‐deficiency syndrome) or (acquired immun* deficiency syndrome) |
| #4 | MeSH descriptor: [Lymphoma, AIDS‐Related] this term only |
| #5 | MeSH descriptor: [Sexually Transmitted Diseases, Viral] this term only |
| #6 | #1 or #2 or #3 or #4 or #5 |
| #7 | [mh ^genotype] or genotype:ti,ab,kw or [mh "genotypic techniques"] or genotypic:ti,ab,kw or genotyping:ti,ab,kw or genotypical:ti,ab,kw (Word variations have been searched) |
| #8 | [mh ^phenotype] or phenotype:ti,ab,kw or phenotypic:ti,ab,kw or phenotyping:ti,ab,kw or phenotypical:ti,ab,kw (Word variations have been searched) |
| #9 | (resistance or resistant):ti,ab,kw (Word variations have been searched) |
| #10 | #7 or #8 or #9 |
| #11 | (test or tests or tested or testing or assay or assays):ti,ab,kw (Word variations have been searched) |
| #12 | #10 and #11 |
| #13 | [mh "drug resistance"] or resistance:ti,ab,kw or resistant:ti,ab,kw (Word variations have been searched) |
| #14 | #6 and #12 and #13 Publication Year from 1989 to xxx, in Trials |
Appendix 2. PubMed search strategy
| Search | Query |
| #11 | Search (((#1 AND #7 AND #8 AND #9))) AND ("1989/01/01"[Date ‐ Publication] : "xxxx/xx/xx"[Date ‐ Publication]) |
| #10 | Search (#1 AND #7 AND #8 AND #9) |
| #9 | Search (randomized controlled trial [pt] OR controlled clinical trial [pt] OR randomized [tiab] OR placebo [tiab] OR drug therapy [sh] OR randomly [tiab] OR trial [tiab] OR groups [tiab] OR cohort studies[mh:noexp] OR cohort[tiab] OR longitudinal studies[mh:noexp] OR longitudinal[tiab] OR follow‐up studies[mh:noexp] OR follow‐up[tiab] OR followup[tiab] OR prospective studies[mh:noexp] OR prospective[tiab] OR retrospective studies[mh:noexp] OR retrospective[tiab] OR epidemiologic studies[mh:noexp]) NOT (animals [mh] NOT humans [mh]) |
| #8 | Search (drug resistance[mh] OR resistance[tiab] OR resistant[tiab]) |
| #7 | Search (#5 AND #6) |
| #6 | Search (test[tiab] OR tests[tiab] OR testing[tiab] OR tested[tiab] OR assay[tiab] OR assays[tiab]) |
| #5 | Search (#2 OR #3 OR #4) |
| #4 | Search (resistance[tiab] OR resistant[tiab]) |
| #3 | Search (phenotype[mh:noexp] OR phenotype[tiab] OR phenotypic[tiab] OR phenotyping[tiab] OR phenotypical[tiab]) |
| #2 | Search (genotype[mh:noexp] OR genotypic techniques[mh] genotype[tiab] OR genotypic[tiab] OR genotyping[tiab] OR genotypical[tiab]) |
| #1 | Search (HIV Infections[MeSH] OR HIV[MeSH] OR hiv[tiab] OR hiv‐1*[tiab] OR hiv‐2*[tiab] OR hiv1[tiab] OR hiv2[tiab] OR hiv infect*[tiab] OR human immunodeficiency virus[tiab] OR human immunedeficiency virus[tiab] OR human immuno‐deficiency virus[tiab] OR human immune‐deficiency virus[tiab] OR ((human immun*[tiab]) AND (deficiency virus[tiab])) OR acquired immunodeficiency syndrome[tiab] OR acquired immunedeficiency syndrome[tiab] OR acquired immuno‐deficiency syndrome[tiab] OR acquired immune‐deficiency syndrome[tiab] OR ((acquired immun*[tiab]) AND (deficiency syndrome[tiab])) |
Appendix 3. Embase search strategy
| No. | Query |
| #17 | #1 AND #7 AND #8 AND #16 |
| #16 | #11 NOT #15 |
| #15 | #12 NOT #14 |
| #14 | #12 AND #13 |
| #13 | 'human'/de OR 'normal human'/de OR 'human cell'/de |
| #12 | 'animal'/de OR 'animal experiment'/de OR 'invertebrate'/de OR 'animal tissue'/de OR 'animal cell'/de OR 'nonhuman'/de |
| #11 | #9 OR #10 |
| #10 | 'randomized controlled trial'/de OR 'randomized controlled trial' OR random*:ab,ti OR trial:ti OR allocat*:ab,ti OR factorial*:ab,ti OR placebo*:ab,ti OR assign*:ab,ti OR volunteer*:ab,ti OR 'crossover procedure'/de OR 'crossover procedure' OR 'double‐blind procedure'/de OR 'double‐blind procedure' OR 'single‐blind procedure'/de OR 'single‐blind procedure' OR (doubl* NEAR/3 blind*):ab,ti OR (singl*:ab,ti AND blind*:ab,ti) OR crossover*:ab,ti OR cross+over*:ab,ti OR (cross NEXT/1 over*):ab,ti |
| #9 | 'prospective study'/de OR prospective:ab,ti OR 'cohort analysis'/de OR cohort:ab,ti OR 'longitudinal study' OR longitudinal:ab,ti OR 'experimental design'/de OR 'retrospective study'/de OR retrospective:ab,ti OR 'follow up'/de OR 'follow+up':ab,ti OR followup:ab,ti |
| #8 | 'drug resistance'/exp OR resistance:ab,ti OR resistant:ab,ti |
| #7 | #5 AND #6 |
| #6 | test:ab,ti OR tests:ab,ti OR testing:ab,ti OR tested:ab,ti OR assay:ab,ti OR assays:ab,ti |
| #5 | #2 OR #3 OR #4 |
| #4 | resistance:ab,ti OR resistant:ab,ti |
| #3 | 'phenotype'/de OR phenotype:ab,ti OR phenotypic:ab,ti OR phenotyping:ab,ti OR genotypical:ab,ti |
| #2 | 'genotyping technique'/de OR genotype:ab,ti OR genotypic:ab,ti OR genotyping:ab,ti OR genotypical:ab,ti |
| #1 | 'human immunodeficiency virus infection'/exp OR 'human immunodeficiency virus'/exp OR 'human immunodeficiency virus':ab,ti OR 'human immuno+deficiency virus':ab,ti OR 'human immunedeficiency virus':ab,ti OR 'human immune+deficiency virus':ab,ti OR hiv:ab,ti OR 'hiv‐1':ab,ti OR 'hiv‐2':ab,ti OR 'acquired immunodeficiency syndrome':ab,ti OR 'acquired immuno+deficiency syndrome':ab,ti OR 'acquired immunedeficiency syndrome':ab,ti OR 'acquired immune+deficiency syndrome':ab,ti |
