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Cochrane Database of Systematic Reviews

Immunostimulants for preventing respiratory tract infection in children

Information

DOI:
https://doi.org/10.1002/14651858.CD004974.pub2Copy DOI
Database:
  1. Cochrane Database of Systematic Reviews
Version published:
  1. 18 October 2006see what's new
Type:
  1. Intervention
Stage:
  1. Review
Cochrane Editorial Group:

  1. Cochrane Acute Respiratory Infections Group

Copyright:
  1. Copyright © 2011 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.

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Authors

  • Blanca Estela Del‐Rio‐Navarro

    Correspondence to: Department of Allergy and Immunology, Hospital Infantil de México "Federico Gómez", Mexico City, Mexico

    [email protected]

    [email protected]

  • Francisco J Espinosa‐Rosales

    Department of Immunology, Instituto Nacional de Pediatría (National Institute of Pediatrics), México D.F., Mexico

  • Vicki Flenady

    Translating Research Into Practice (TRIP) Centre ‐ Mater Medical Research Institute, Mater Health Services, Woolloongabba, Australia

  • Juan JL Sienra‐Monge

    Department of Allergy and Immunology, Hospital Infantil de México "Federico Gómez", Mexico City, Mexico

Contributions of authors

Dr Blanca Estela Del‐Rio‐Navarro (BN) searched for papers, extracted the relevant data, analyzed data and co‐wrote the review.
Dr Juan JL Sienra‐Monge (JSM) searched for papers, extracted the relevant data and co‐wrote the review.
Dr Francisco Espinosa‐Rosales (FER) searched for papers, analyzed data and co‐wrote the review.
Vicki Flenady (VF) co‐wrote and made corrections to the review.

Sources of support

Internal sources

  • Allergy and Clinical Immunolgy Service, Children Hospital of Mexico Federico Gomez, Mexico.

    The review was supported by the local institution

External sources

  • No sources of support supplied

Declarations of interest

Dr Arturo Berber was the medical manager for OM‐85 BV (Broncho‐Vaxom) in Mexico for BASF Pharma Mexico (Química Knoll de México) from 1995 to 2001. He was also the contact author of the initial protocol until he graciously stepped down because of a potential conflict of interest.

Dr Blanca Del Rio‐Navarro and Dr Sienra‐Monge were involved in the following IS trial: Del‐Rio‐Navarro BE, Luis Sienra‐Monge JJ, Berber A, Torres‐Alcantara S, Avila‐Castanon L, Gomez‐Barreto D. Use of OM‐85 BV in children suffering from recurrent respiratory tract infections and subnormal IgG subclass levels. Allergologia et Immunopathologia (Madrid) 2003 Jan‐Feb;31(1):7‐13.

Dr Blanca Del Rio‐Navarro was involved in the following IS trials: Field J, Gomez‐Barreto D, Del‐Rio‐Navarro BE, Berber A. Use of OM‐85 BV in primary prevention of acute respiratory tract infections in children in orphanages Current Therapeutics Research, Clinical and Experimental 1998 59:6 (407‐18); Berber AC, Del‐Rio‐Navarro BE. Use of Broncho‐Vaxom in private practice: phase IV trial in 587 children. Clinical Therapeutics 1996 Nov‐Dec;18(6):1068‐79.

Acknowledgements

We especially acknowledged the great editorial work of Liz Dooley. We thank Arturo Berber for his contribution to the protocol. The authors also wish to thank the following people for commenting on the draft review of the first version: Chanpen Choprapawon, Ville Peltola, Richard Shoemaker and Ludovic Reveiz; and to Anne Lyddiatt, Ville Peltola, Sree Nair and Ludovic Reveiz for the comments on the updated draft review.

Version history

Published

Title

Stage

Authors

Version

2006 Oct 18

Immunostimulants for preventing respiratory tract infection in children

Review

Blanca Estela Del‐Rio‐Navarro, Francisco J Espinosa‐Rosales, Vicki Flenady, Juan JL Sienra‐Monge

https://doi.org/10.1002/14651858.CD004974.pub2

2004 Oct 18

Immunostimulants for preventing respiratory tract infection in children

Protocol

Arturo Berber, Blanca Estela Del‐Rio‐Navarro, Vicki Flenady, Juan JL Sienra‐Monge

https://doi.org/10.1002/14651858.CD004974

PICOs

Population
Intervention
Comparison
Outcome

The PICO model is widely used and taught in evidence-based health care as a strategy for formulating questions and search strategies and for characterizing clinical studies or meta-analyses. PICO stands for four different potential components of a clinical question: Patient, Population or Problem; Intervention; Comparison; Outcome.

See more on using PICO in the Cochrane Handbook.