Scolaris Content Display Scolaris Content Display

Children not cured or substantially improved at follow‐up
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Figure 1

Children not cured or substantially improved at follow‐up

Comparison 1 Clinical failure, Outcome 1 Children not cured or substantially improved at follow‐up (using 'intention to treat' analysis).
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Analysis 1.1

Comparison 1 Clinical failure, Outcome 1 Children not cured or substantially improved at follow‐up (using 'intention to treat' analysis).

Comparison 1 Clinical failure, Outcome 2 Children not cured or substantially improved at follow‐up (excluding those known to have B.Pertussis).
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Analysis 1.2

Comparison 1 Clinical failure, Outcome 2 Children not cured or substantially improved at follow‐up (excluding those known to have B.Pertussis).

Comparison 1 Clinical failure, Outcome 3 Children not cured or substantially improved at follow‐up (using available data only).
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Analysis 1.3

Comparison 1 Clinical failure, Outcome 3 Children not cured or substantially improved at follow‐up (using available data only).

Comparison 2 Illness progression, Outcome 1 Participants with progression of disease resulting in additional medical therapy required.
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Analysis 2.1

Comparison 2 Illness progression, Outcome 1 Participants with progression of disease resulting in additional medical therapy required.

Comparison 3 Adverse events (reaction to medications), Outcome 1 Reaction to medications (vomiting, diarrhoea, rash).
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Analysis 3.1

Comparison 3 Adverse events (reaction to medications), Outcome 1 Reaction to medications (vomiting, diarrhoea, rash).

Comparison 1. Clinical failure

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Children not cured or substantially improved at follow‐up (using 'intention to treat' analysis) Show forest plot

2

140

Odds Ratio (M‐H, Fixed, 95% CI)

0.13 [0.06, 0.31]

2 Children not cured or substantially improved at follow‐up (excluding those known to have B.Pertussis) Show forest plot

2

128

Odds Ratio (M‐H, Fixed, 95% CI)

0.13 [0.05, 0.30]

3 Children not cured or substantially improved at follow‐up (using available data only) Show forest plot

2

124

Odds Ratio (M‐H, Fixed, 95% CI)

0.12 [0.05, 0.29]

Figures and Tables -
Comparison 1. Clinical failure
Comparison 2. Illness progression

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Participants with progression of disease resulting in additional medical therapy required Show forest plot

2

125

Odds Ratio (M‐H, Fixed, 95% CI)

0.10 [0.03, 0.34]

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Comparison 2. Illness progression
Comparison 3. Adverse events (reaction to medications)

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Reaction to medications (vomiting, diarrhoea, rash) Show forest plot

2

128

Odds Ratio (M‐H, Fixed, 95% CI)

1.38 [0.31, 6.08]

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Comparison 3. Adverse events (reaction to medications)