Scolaris Content Display Scolaris Content Display

Comparison 1 Mortality, Outcome 1 28 day mortality.
Figures and Tables -
Analysis 1.1

Comparison 1 Mortality, Outcome 1 28 day mortality.

Comparison 2 Adverse events, Outcome 1 Any adverse event (including organ dysfunction).
Figures and Tables -
Analysis 2.1

Comparison 2 Adverse events, Outcome 1 Any adverse event (including organ dysfunction).

Comparison 2 Adverse events, Outcome 2 Adult respiratory distress syndrome.
Figures and Tables -
Analysis 2.2

Comparison 2 Adverse events, Outcome 2 Adult respiratory distress syndrome.

Comparison 2 Adverse events, Outcome 3 Disseminated intravascular coagulation.
Figures and Tables -
Analysis 2.3

Comparison 2 Adverse events, Outcome 3 Disseminated intravascular coagulation.

Comparison 2 Adverse events, Outcome 4 Acute renal failure.
Figures and Tables -
Analysis 2.4

Comparison 2 Adverse events, Outcome 4 Acute renal failure.

Comparison 2 Adverse events, Outcome 5 Septic shock.
Figures and Tables -
Analysis 2.5

Comparison 2 Adverse events, Outcome 5 Septic shock.

Comparison 1. Mortality

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 28 day mortality Show forest plot

4

1955

Odds Ratio (M‐H, Fixed, 95% CI)

0.99 [0.77, 1.29]

Figures and Tables -
Comparison 1. Mortality
Comparison 2. Adverse events

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Any adverse event (including organ dysfunction) Show forest plot

4

1955

Odds Ratio (M‐H, Fixed, 95% CI)

0.91 [0.73, 1.14]

2 Adult respiratory distress syndrome Show forest plot

3

1254

Odds Ratio (M‐H, Fixed, 95% CI)

0.91 [0.54, 1.54]

3 Disseminated intravascular coagulation Show forest plot

3

1254

Odds Ratio (M‐H, Fixed, 95% CI)

0.43 [0.15, 1.22]

4 Acute renal failure Show forest plot

3

1254

Odds Ratio (M‐H, Fixed, 95% CI)

0.66 [0.27, 1.63]

5 Septic shock Show forest plot

2

1236

Odds Ratio (M‐H, Fixed, 95% CI)

0.60 [0.34, 1.08]

Figures and Tables -
Comparison 2. Adverse events