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Cochrane Database of Systematic Reviews

Noninvasive positive pressure ventilation as a weaning strategy for intubated adults with respiratory failure

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Information

DOI:
https://doi.org/10.1002/14651858.CD004127Copy DOI
Database:
  1. Cochrane Database of Systematic Reviews
Version published:
  1. 20 October 2003see what's new
Type:
  1. Intervention
Stage:
  1. Review
Cochrane Editorial Group:
  1. Cochrane Anaesthesia Group

Copyright:
  1. Copyright © 2010 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.

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Authors

  • Karen E. A. Burns

    Correspondence to: Critical Care Medicine, London Health Sciences Centre, London, Canada

    [email protected]

  • Neill K. J. Adhikari

    Department of Medicine, Sunnybrook and Women's College Health Centre, Toronto, Canada

  • Maureen O. Meade

    Medicine and Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Canada

Contributions of authors

Karen Burns ‐ KB proposed the research question and title and designed the protocol. KB conducted the search strategy, retrieved relevant articles, assessed methodologic quality of retrieved articles and abstracted data as the primary reviewer. KB conducted the statistical analysis and prepared the final review.

Neill Adhikari ‐ NA conducted the search strategy, assessed methodologic quality of retrieved articles and abstracted data as the second reviewer. NA revised the final review for important intellectual content.

Maureen Meade ‐ MM supervised the methodologic integrity of the review. MM reviewed the completed review for methodologic and scientific integrity.

Sources of support

Internal sources

  • McMaster University, Canada.

External sources

  • Dr. Burns is the recipient of a Canadian Lung Association/Merck Frosst Postdoctoral Fellowship, Canada.

  • Dr. Meade is a Peter Lougheed Scholar of the Canadian Institute of Health Research, Canada.

Declarations of interest

None known

Acknowledgements

We would like to thank the members of the Cochrane editorial team including Dr Harald Herkner, Prof Nathan Pace, Dr Sean Keenan, Dr Felix Ram, Nete Villebo, Janet Wale and Amy Godfrey Arkle. We would also like to thank the authors of the primary research who provided additional information pertinent to the design and outcomes of their respective clinical trials. In addition, we are grateful to Mr Feng Zhao for translation of an included article.

Version history

Published

Title

Stage

Authors

Version

2013 Dec 09

Noninvasive positive‐pressure ventilation as a weaning strategy for intubated adults with respiratory failure

Review

Karen EA Burns, Maureen O Meade, Azra Premji, Neill KJ Adhikari

https://doi.org/10.1002/14651858.CD004127.pub3

2010 Aug 04

Noninvasive positive pressure ventilation as a weaning strategy for intubated adults with respiratory failure

Review

Karen EA Burns, Neill KJ Adhikari, Sean P Keenan, Maureen O Meade

https://doi.org/10.1002/14651858.CD004127.pub2

2003 Oct 20

Noninvasive positive pressure ventilation as a weaning strategy for intubated adults with respiratory failure

Review

Karen E. A. Burns, Neill K. J. Adhikari, Maureen O. Meade

https://doi.org/10.1002/14651858.CD004127

Notes

In the previously published protocol, as part of an a priori sensitivity analysis, we stated that we would assess the impact of the etiology of respiratory failure (COPD vs non‐COPD) on (i) the proportion of weaning failures and (ii) mortality. In the review, we identified two studies restricted to patients with COPD and three studies with mixed patient populations. In the absence of individual patient data, we compared studies restricted to COPD patients versus those with mixed patient populations. To explore for potential differences in response to NPPV we compared studies enrolling at least 50% COPD patients to those enrolling less than 50% COPD on mortality.

To search Embase: we used the following Emtree terms: respiratory failure (explode), positive end‐expiratory pressure (explode) and weaning (explode). In addition, we used the Emtag: artificial ventilation.

In the protocol, we stated that the MEDLINE search strategy would be limited to include the following publication types: clinical trials, controlled clinical trials, randomized controlled trials, multicenter studies and meta‐analyses. In the review we did not limit the most recent literature search, conducted in July 2003, by publication type.

PICOs

Population
Intervention
Comparison
Outcome

The PICO model is widely used and taught in evidence-based health care as a strategy for formulating questions and search strategies and for characterizing clinical studies or meta-analyses. PICO stands for four different potential components of a clinical question: Patient, Population or Problem; Intervention; Comparison; Outcome.

See more on using PICO in the Cochrane Handbook.