Slow advancement of enteral feed volumes to prevent necrotising enterocolitis in very low birth weight infants
Information
- DOI:
- https://doi.org/10.1002/14651858.CD001241.pub5Copy DOI
- Database:
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- Cochrane Database of Systematic Reviews
- Version published:
-
- 02 December 2014see what's new
- Type:
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- Intervention
- Stage:
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- Review
- Cochrane Editorial Group:
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Cochrane Neonatal Group
- Copyright:
-
- Copyright © 2014 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.
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Authors
Contributions of authors
Drs Young and McGuire updated the search, independently determined the eligibility of identified studies, assessed the methodological quality of the included trials, and extracted the relevant information and data.
Sources of support
Internal sources
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Centre for Reviews and Dissemination, Hull York Medical School, UK.
External sources
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National Institute for Health Research (NIHR), UK.
NIHR Cochrane Programme Grant (13/89/12)
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Eunice Kennedy Shriver National Institute of Child Health and Human Development National Institutes of Health, Department of Health and Human Services, USA.
Editorial support of the Cochrane Neonatal Review Group has been funded with Federal funds from the Eunice Kennedy Shriver National Institute of Child Health and Human Development National Institutes of Health, Department of Health and Human Services, USA, under Contract No. HHSN267200603418C.
Declarations of interest
None
Acknowledgements
We are grateful to Drs Namasivayam Ambalavanan and Kanya Mukhopadhyay for providing further details and data (Rayyis 1999; Mukhopadhyay 2014).
This report is independent research funded by a UK National Institute for Health Research Grant (NIHR) Cochrane Programme Grant (13/89/12). The views expressed in this publication are those of the authors and not necessarily those of the National Health Service, the NIHR, or the UK Department of Health.
Version history
| Published | Title | Stage | Authors | Version |
| 2021 Aug 24 | Slow advancement of enteral feed volumes to prevent necrotising enterocolitis in very low birth weight infants | Review | Sam J Oddie, Lauren Young, William McGuire | |
| 2017 Aug 30 | Slow advancement of enteral feed volumes to prevent necrotising enterocolitis in very low birth weight infants | Review | Sam J Oddie, Lauren Young, William McGuire | |
| 2015 Oct 15 | Slow advancement of enteral feed volumes to prevent necrotising enterocolitis in very low birth weight infants | Review | Jessie Morgan, Lauren Young, William McGuire | |
| 2014 Dec 02 | Slow advancement of enteral feed volumes to prevent necrotising enterocolitis in very low birth weight infants | Review | Jessie Morgan, Lauren Young, William McGuire | |
| 2013 Mar 28 | Slow advancement of enteral feed volumes to prevent necrotising enterocolitis in very low birth weight infants | Review | Jessie Morgan, Lauren Young, William McGuire | |
| 2011 Mar 16 | Slow advancement of enteral feed volumes to prevent necrotising enterocolitis in very low birth weight infants | Review | Jessie Morgan, Lauren Young, William McGuire | |
| 2008 Apr 23 | Slow advancement of enteral feed volumes to prevent necrotising enterocolitis in very low birth weight infants | Review | William McGuire, Sarah Bombell | |
| 1998 Oct 26 | Rapid versus slow rate of advancement of feedings for promoting growth and preventing necrotizing enterocolitis in parenterally fed low‐birth‐weight infants | Review | Kathleen A Kennedy, Jon E Tyson | |
Keywords
MeSH
Medical Subject Headings (MeSH) Keywords
- *Infant, Very Low Birth Weight;
- Enteral Nutrition [adverse effects, *methods];
- Enterocolitis, Necrotizing [epidemiology, etiology, *prevention & control];
- Incidence;
- Infant, Low Birth Weight [growth & development];
- Infant, Premature [growth & development];
- Infant, Premature, Diseases [etiology, *prevention & control];
- Parenteral Nutrition [adverse effects];
- Randomized Controlled Trials as Topic;
Medical Subject Headings Check Words
Humans; Infant, Newborn;
PICOs
Forest plot of comparison: 1 Slow versus faster rates of feed advancement, outcome: 1.1 Incidence of necrotising enterocolitis.
Forest plot of comparison: 1 Slow versus faster rates of feed advancement, outcome: 1.2 Mortality.
Forest plot of comparison: 1 Slow versus faster rates of feed advancement, outcome: 1.3 Feeds intolerance (causing interruption of enteral feeding).
Forest plot of comparison: 1 Slow versus faster rates of feed advancement, outcome: 1.4 Incidence of invasive infection.
Risk of bias graph: review authors' judgements about each risk of bias item presented as percentages across all included studies.
Comparison 1 Slow versus faster rates of feed advancement, Outcome 1 Incidence of necrotising enterocolitis.
Comparison 1 Slow versus faster rates of feed advancement, Outcome 2 Mortality.
Comparison 1 Slow versus faster rates of feed advancement, Outcome 3 Feeds intolerance (causing interruption of enteral feeding).
Comparison 1 Slow versus faster rates of feed advancement, Outcome 4 Incidence of invasive infection.
| Outcome or subgroup title | No. of studies | No. of participants | Statistical method | Effect size |
| 1 Incidence of necrotising enterocolitis Show forest plot | 6 | Risk Ratio (M‐H, Fixed, 95% CI) | Subtotals only | |
| 1.1 All trials | 6 | 618 | Risk Ratio (M‐H, Fixed, 95% CI) | 0.96 [0.55, 1.70] |
| 1.2 Trials in which most infants were small for gestational age or growth restricted | 2 | 83 | Risk Ratio (M‐H, Fixed, 95% CI) | 0.34 [0.06, 2.04] |
| 2 Mortality Show forest plot | 5 | Risk Ratio (M‐H, Fixed, 95% CI) | Subtotals only | |
| 2.1 All trials | 5 | 460 | Risk Ratio (M‐H, Fixed, 95% CI) | 1.57 [0.92, 2.70] |
| 2.2 Trials in which most infants were small for gestational age or growth restricted | 2 | 83 | Risk Ratio (M‐H, Fixed, 95% CI) | 2.13 [1.02, 4.47] |
| 3 Feeds intolerance (causing interruption of enteral feeding) Show forest plot | 4 | 275 | Risk Ratio (M‐H, Fixed, 95% CI) | 1.23 [0.87, 1.73] |
| 4 Incidence of invasive infection Show forest plot | 3 | 222 | Risk Ratio (M‐H, Fixed, 95% CI) | 1.58 [0.81, 3.09] |
