Scolaris Content Display Scolaris Content Display

Comparison 1 Magnesium sulphate versus phenytoin, Outcome 1 Maternal death.
Figures and Tables -
Analysis 1.1

Comparison 1 Magnesium sulphate versus phenytoin, Outcome 1 Maternal death.

Comparison 1 Magnesium sulphate versus phenytoin, Outcome 2 Recurrence of convulsions.
Figures and Tables -
Analysis 1.2

Comparison 1 Magnesium sulphate versus phenytoin, Outcome 2 Recurrence of convulsions.

Comparison 1 Magnesium sulphate versus phenytoin, Outcome 3 Respiratory depression.
Figures and Tables -
Analysis 1.3

Comparison 1 Magnesium sulphate versus phenytoin, Outcome 3 Respiratory depression.

Comparison 1 Magnesium sulphate versus phenytoin, Outcome 4 Pulmonary oedema.
Figures and Tables -
Analysis 1.4

Comparison 1 Magnesium sulphate versus phenytoin, Outcome 4 Pulmonary oedema.

Comparison 1 Magnesium sulphate versus phenytoin, Outcome 5 Pneumonia.
Figures and Tables -
Analysis 1.5

Comparison 1 Magnesium sulphate versus phenytoin, Outcome 5 Pneumonia.

Comparison 1 Magnesium sulphate versus phenytoin, Outcome 6 Ventilation.
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Analysis 1.6

Comparison 1 Magnesium sulphate versus phenytoin, Outcome 6 Ventilation.

Comparison 1 Magnesium sulphate versus phenytoin, Outcome 7 Renal failure.
Figures and Tables -
Analysis 1.7

Comparison 1 Magnesium sulphate versus phenytoin, Outcome 7 Renal failure.

Comparison 1 Magnesium sulphate versus phenytoin, Outcome 8 Cerebrovascular accident.
Figures and Tables -
Analysis 1.8

Comparison 1 Magnesium sulphate versus phenytoin, Outcome 8 Cerebrovascular accident.

Comparison 1 Magnesium sulphate versus phenytoin, Outcome 9 Liver failure.
Figures and Tables -
Analysis 1.9

Comparison 1 Magnesium sulphate versus phenytoin, Outcome 9 Liver failure.

Comparison 1 Magnesium sulphate versus phenytoin, Outcome 10 Cardiac arrest.
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Analysis 1.10

Comparison 1 Magnesium sulphate versus phenytoin, Outcome 10 Cardiac arrest.

Comparison 1 Magnesium sulphate versus phenytoin, Outcome 11 Coagulopathy.
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Analysis 1.11

Comparison 1 Magnesium sulphate versus phenytoin, Outcome 11 Coagulopathy.

Comparison 1 Magnesium sulphate versus phenytoin, Outcome 12 Admission to intensive care unit.
Figures and Tables -
Analysis 1.12

Comparison 1 Magnesium sulphate versus phenytoin, Outcome 12 Admission to intensive care unit.

Comparison 1 Magnesium sulphate versus phenytoin, Outcome 15 Caesarean section.
Figures and Tables -
Analysis 1.15

Comparison 1 Magnesium sulphate versus phenytoin, Outcome 15 Caesarean section.

Comparison 1 Magnesium sulphate versus phenytoin, Outcome 16 Labour > 8 hours.
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Analysis 1.16

Comparison 1 Magnesium sulphate versus phenytoin, Outcome 16 Labour > 8 hours.

Comparison 1 Magnesium sulphate versus phenytoin, Outcome 18 Blood loss at delivery > 500 ml.
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Analysis 1.18

Comparison 1 Magnesium sulphate versus phenytoin, Outcome 18 Blood loss at delivery > 500 ml.

Comparison 1 Magnesium sulphate versus phenytoin, Outcome 20 Mortality for the fetus or infant.
Figures and Tables -
Analysis 1.20

Comparison 1 Magnesium sulphate versus phenytoin, Outcome 20 Mortality for the fetus or infant.

Comparison 1 Magnesium sulphate versus phenytoin, Outcome 21 Apgar scores.
Figures and Tables -
Analysis 1.21

Comparison 1 Magnesium sulphate versus phenytoin, Outcome 21 Apgar scores.

Comparison 1 Magnesium sulphate versus phenytoin, Outcome 22 Utilization of special care baby unit (SCBU).
Figures and Tables -
Analysis 1.22

Comparison 1 Magnesium sulphate versus phenytoin, Outcome 22 Utilization of special care baby unit (SCBU).

Comparison 1 Magnesium sulphate versus phenytoin, Outcome 23 Death or in SCBU > 7 days.
Figures and Tables -
Analysis 1.23

Comparison 1 Magnesium sulphate versus phenytoin, Outcome 23 Death or in SCBU > 7 days.

Comparison 1. Magnesium sulphate versus phenytoin

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Maternal death Show forest plot

2

797

Risk Ratio (M‐H, Fixed, 95% CI)

0.50 [0.24, 1.05]

2 Recurrence of convulsions Show forest plot

5

895

Risk Ratio (M‐H, Fixed, 95% CI)

0.31 [0.20, 0.47]

3 Respiratory depression Show forest plot

1

775

Risk Ratio (M‐H, Fixed, 95% CI)

0.71 [0.46, 1.09]

4 Pulmonary oedema Show forest plot

2

825

Risk Ratio (M‐H, Fixed, 95% CI)

1.00 [0.47, 2.10]

5 Pneumonia Show forest plot

1

775

Risk Ratio (M‐H, Fixed, 95% CI)

0.44 [0.24, 0.79]

6 Ventilation Show forest plot

1

775

Risk Ratio (M‐H, Fixed, 95% CI)

0.66 [0.49, 0.90]

7 Renal failure Show forest plot

2

825

Risk Ratio (M‐H, Fixed, 95% CI)

1.48 [0.94, 2.32]

8 Cerebrovascular accident Show forest plot

1

775

Risk Ratio (M‐H, Fixed, 95% CI)

0.54 [0.20, 1.46]

9 Liver failure Show forest plot

1

775

Risk Ratio (M‐H, Fixed, 95% CI)

1.50 [0.54, 4.16]

10 Cardiac arrest Show forest plot

1

775

Risk Ratio (M‐H, Fixed, 95% CI)

1.16 [0.39, 3.43]

11 Coagulopathy Show forest plot

1

775

Risk Ratio (M‐H, Fixed, 95% CI)

0.88 [0.66, 1.16]

12 Admission to intensive care unit Show forest plot

1

775

Risk Ratio (M‐H, Fixed, 95% CI)

0.67 [0.50, 0.89]

15 Caesarean section Show forest plot

2

650

Risk Ratio (M‐H, Fixed, 95% CI)

0.94 [0.86, 1.03]

16 Labour > 8 hours Show forest plot

1

628

Risk Ratio (M‐H, Fixed, 95% CI)

1.19 [0.85, 1.67]

18 Blood loss at delivery > 500 ml Show forest plot

1

628

Risk Ratio (M‐H, Fixed, 95% CI)

0.98 [0.74, 1.30]

20 Mortality for the fetus or infant Show forest plot

2

Risk Ratio (M‐H, Fixed, 95% CI)

Subtotals only

20.1 Stillbirth

2

665

Risk Ratio (M‐H, Fixed, 95% CI)

0.83 [0.61, 1.13]

20.2 Perinatal death

2

665

Risk Ratio (M‐H, Fixed, 95% CI)

0.85 [0.67, 1.09]

20.3 Neonatal death

2

665

Risk Ratio (M‐H, Fixed, 95% CI)

0.95 [0.59, 1.53]

21 Apgar scores Show forest plot

1

Risk Ratio (M‐H, Fixed, 95% CI)

Subtotals only

21.1 Apgar < 7 at 1 minute

1

518

Risk Ratio (M‐H, Fixed, 95% CI)

0.78 [0.66, 0.93]

21.2 Apgar < 7 at 5 minutes

1

518

Risk Ratio (M‐H, Fixed, 95% CI)

0.86 [0.52, 1.43]

22 Utilization of special care baby unit (SCBU) Show forest plot

1

Risk Ratio (M‐H, Fixed, 95% CI)

Subtotals only

22.1 Admission to SCBU

1

518

Risk Ratio (M‐H, Fixed, 95% CI)

0.73 [0.58, 0.91]

22.3 In SCBU > 7 days

1

518

Risk Ratio (M‐H, Fixed, 95% CI)

0.53 [0.33, 0.86]

23 Death or in SCBU > 7 days Show forest plot

1

643

Risk Ratio (M‐H, Fixed, 95% CI)

0.77 [0.63, 0.95]

Figures and Tables -
Comparison 1. Magnesium sulphate versus phenytoin