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Comparison 1 Passiflora vs Benzodiazepines, Outcome 1 Lack of moderate/marked improvement (FGIR).
Figures and Tables -
Analysis 1.1

Comparison 1 Passiflora vs Benzodiazepines, Outcome 1 Lack of moderate/marked improvement (FGIR).

Comparison 1 Passiflora vs Benzodiazepines, Outcome 2 Number of subjects reporting side‐effects.
Figures and Tables -
Analysis 1.2

Comparison 1 Passiflora vs Benzodiazepines, Outcome 2 Number of subjects reporting side‐effects.

Comparison 1 Passiflora vs Benzodiazepines, Outcome 3 Side‐effects.
Figures and Tables -
Analysis 1.3

Comparison 1 Passiflora vs Benzodiazepines, Outcome 3 Side‐effects.

Comparison 1 Passiflora vs Benzodiazepines, Outcome 4 Dropout.
Figures and Tables -
Analysis 1.4

Comparison 1 Passiflora vs Benzodiazepines, Outcome 4 Dropout.

Comparison 1 Passiflora vs Benzodiazepines, Outcome 5 Impairment of job performance.
Figures and Tables -
Analysis 1.5

Comparison 1 Passiflora vs Benzodiazepines, Outcome 5 Impairment of job performance.

Comparison 1. Passiflora vs Benzodiazepines

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Lack of moderate/marked improvement (FGIR) Show forest plot

1

Risk Ratio (M‐H, Random, 95% CI)

Subtotals only

1.1 Mexazolam

1

134

Risk Ratio (M‐H, Random, 95% CI)

1.13 [0.85, 1.49]

2 Number of subjects reporting side‐effects Show forest plot

1

134

Risk Ratio (M‐H, Random, 95% CI)

0.90 [0.46, 1.78]

3 Side‐effects Show forest plot

2

Risk Ratio (M‐H, Random, 95% CI)

Subtotals only

3.1 agression

1

32

Risk Ratio (M‐H, Random, 95% CI)

0.0 [0.0, 0.0]

3.2 allergic reaction

2

166

Risk Ratio (M‐H, Random, 95% CI)

0.94 [0.22, 4.07]

3.3 ataxia

1

32

Risk Ratio (M‐H, Random, 95% CI)

0.50 [0.11, 2.35]

3.4 confusion

1

32

Risk Ratio (M‐H, Random, 95% CI)

1.0 [0.30, 3.32]

3.5 disinhibition

1

32

Risk Ratio (M‐H, Random, 95% CI)

0.0 [0.0, 0.0]

3.6 dizziness

2

166

Risk Ratio (M‐H, Random, 95% CI)

0.89 [0.44, 1.82]

3.7 drowsiness

2

166

Risk Ratio (M‐H, Random, 95% CI)

0.56 [0.20, 1.59]

3.8 dyspnea

1

32

Risk Ratio (M‐H, Random, 95% CI)

0.2 [0.01, 3.86]

3.9 hyporeflexia

1

32

Risk Ratio (M‐H, Random, 95% CI)

0.33 [0.01, 7.62]

3.10 respiratory depression

1

32

Risk Ratio (M‐H, Random, 95% CI)

0.14 [0.01, 2.56]

3.11 slurred speech

1

32

Risk Ratio (M‐H, Random, 95% CI)

0.0 [0.0, 0.0]

3.12 abdominal fullness

1

134

Risk Ratio (M‐H, Random, 95% CI)

0.38 [0.02, 9.04]

3.13 abnormality of salivation

1

134

Risk Ratio (M‐H, Random, 95% CI)

3.38 [0.14, 81.39]

3.14 anorexia

1

134

Risk Ratio (M‐H, Random, 95% CI)

5.63 [0.28, 114.99]

3.15 blurred vision

1

134

Risk Ratio (M‐H, Random, 95% CI)

3.38 [0.14, 81.39]

3.16 chest discomfort

1

134

Risk Ratio (M‐H, Random, 95% CI)

3.38 [0.14, 81.39]

3.17 constipation

1

134

Risk Ratio (M‐H, Random, 95% CI)

0.38 [0.02, 9.04]

3.18 diarrhea

1

134

Risk Ratio (M‐H, Random, 95% CI)

5.63 [0.28, 114.99]

3.19 discouragement

1

134

Risk Ratio (M‐H, Random, 95% CI)

0.38 [0.02, 9.04]

3.20 fatigue

1

134

Risk Ratio (M‐H, Random, 95% CI)

5.63 [0.28, 114.99]

3.21 headache

1

134

Risk Ratio (M‐H, Random, 95% CI)

0.38 [0.02, 9.04]

3.22 heart pressure

1

134

Risk Ratio (M‐H, Random, 95% CI)

3.38 [0.14, 81.39]

3.23 inarticulateness

1

134

Risk Ratio (M‐H, Random, 95% CI)

0.38 [0.02, 9.04]

3.24 light head feeling

1

134

Risk Ratio (M‐H, Random, 95% CI)

0.23 [0.01, 4.60]

3.25 nausea

1

134

Risk Ratio (M‐H, Random, 95% CI)

0.38 [0.02, 9.04]

3.26 numbness

1

134

Risk Ratio (M‐H, Random, 95% CI)

1.13 [0.07, 17.65]

3.27 stomach ache

1

134

Risk Ratio (M‐H, Random, 95% CI)

1.13 [0.07, 17.65]

3.28 thirst

1

134

Risk Ratio (M‐H, Random, 95% CI)

0.38 [0.02, 9.04]

3.29 weakness

1

134

Risk Ratio (M‐H, Random, 95% CI)

3.38 [0.14, 81.39]

4 Dropout Show forest plot

2

170

Risk Ratio (M‐H, Random, 95% CI)

1.43 [0.77, 2.69]

4.1 Oxazepam

1

36

Risk Ratio (M‐H, Random, 95% CI)

1.0 [0.16, 6.35]

4.2 Mexazolam

1

134

Risk Ratio (M‐H, Random, 95% CI)

1.50 [0.77, 2.93]

5 Impairment of job performance Show forest plot

1

32

Risk Ratio (M‐H, Random, 95% CI)

0.67 [0.38, 1.17]

Figures and Tables -
Comparison 1. Passiflora vs Benzodiazepines