Endovascular repair compared with conventional open surgery for TAAAs

Patient or population: people with a diagnosis of thoracoabdominal aortic aneurysm

Settings: hospital ‐ elective and emergency

Intervention: endovascular repair

Comparison: conventional OSR

Prevention of aneurysm rupture (number of participants without a rupture) (5 years)

Aneurysm‐related mortality (30 days)

Aneurysm‐related mortality (12 months)

All‐cause mortality (5 years)

Spinal cord ischaemia (paraplegia, paraparesis) (5 years)

Visceral arterial branch compromise causing mesenteric ischaemia or renal failure (5 years)

Rate of reintervention (5 years)

*The risk in the intervention group (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI).
CI: confidence interval; OSR: open surgical repair; TAAs: thoracoabdominal aortic aneurysms

GRADE Working Group grades of evidence
High certainty: we are very confident that the true effect lies close to that of the estimate of the effect
Moderate certainty: we are moderately confident in the effect estimate; the true effect is likely to be close to the estimate of the effect, but there is a possibility that it is substantially different
Low certainty: our confidence in the effect estimate is limited; the true effect may be substantially different from the estimate of the effect
Very low certainty: we have very little confidence in the effect estimate; the true effect is likely to be substantially different from the estimate of effect