MEDLINE Ovid 1946 to February Week 4 2019

Searched 5 March 2019. 45 records were retrieved, none of which related to included studies in this review.

1 exp Lipids/
2 fatty acid$.tw,kf.
3 Docosahexaenoic acid.tw,kf.
4 Eicosapentaenoic Acid$.tw,kf.
5 PUFA$.tw,kf.
6 lipid.tw,kf.
7 (omega 3$ or omega 6$).tw,kf.
8 (soy$ or peanut or groundnut or whey or sesame or cashew or chickpea or oil$).tw,kf.
9 or/1‐8
10 Dietary Supplements/
11 Food, fortified/
12 ((diet$ or food$) adj3 (fortif$ or enrich$ or supplement$)).tw,kf.
13 (complement$ adj3 (food$ or feed$)).tw,kf.
14 "Ready to use".tw,kf.
15 (RUSF or RUTF).tw,kf.
16 "point of use".tw,kf. )
17 (home$ adj2 fortif$).tw,kf.
18 or/10‐17
19 9 and 18
20 (lipid$ adj3 nutrient$).tw,kf.
21 (lipid$ adj3 supplement$).tw,kf.
22 lipid based.tw,kf.
23 (lipid$ adj3 fortif$).tw,kf.
24 (lipid$ adj3 enrich$).tw,kf.
25 (lipid$ adj2 emuls$).tw,kf.
26 (lipid$ adj2 formulation$).tw,kf.
27 (Lipid$ adj3 powder$).tw,kf.
28 (lipid adj3 spread$).tw,kf.
29 (lipid$ adj3 paste$).tw,kf.
30 (Nutributter$ or Plumpy$).tw,kf.
31 (LBNS$ or LNS$1 or iLiNS).tw,kf.
32 or/20‐31
33 19 or 32 (43056)
34 Infant/ (753966)
35 (baby or babies or infant$ or toddler$ or child$).tw. (1425823)
36 34 or 35 (1743645)
37 33 and 36 (3151)
38 exp animals/ not humans.sh.
39 37 not 38
40 (comment or "corrected and republished article" or editorial or "expression of concern" or published erratum or retracted publication or "retraction of publication").pt.
41 (comment or corrected or correction or corrigendum or "expression of concern" or erratum or retracted or retraction).ti.
42 40 or 41
43 39 and 42

Embase Ovid 1974 to 2019 March 04

Searched 5 March 2019. records were retreived, none of which related to included studies in this review.

1 exp Lipids/
2 fatty acid$.tw,kw.
3 Docosahexaenoic acid.tw,kw.
4 Eicosapentaenoic Acid$.tw,kw.
5 PUFA$.tw,kw.
6 lipid$.tw,kw.
7 (omega 3$ or omega 6$).tw,kw.
8 (soy$ or peanut or groundnut or whey or sesame or cashew or chickpea or oil$).tw,kw.
9 or/1‐8
10 dietary supplement/
11 fortified food/
12 ((diet$ or food$) adj3 (fortif$ or enrich$ or supplement$)).tw,kw.
13 (complement$ adj3 (food$ or feed$)).tw,kw.
14 "Ready to use".tw,kw.
15 (RUSF or RUTF).tw,kw.
16 "point of use".tw,kw.
17 (home$ adj2 fortif$).tw,kw.
18 or/10‐17
19 9 and 18
20 lipid based.tw,kw.
21 (lipid$ adj3 nutrient$).tw,kw.
22 (lipid$ adj3 supplement$).tw,kw.
23 (lipid$ adj3 fortif$).tw,kw.
24 (lipid$ adj3 enrich$).tw,kw.
25 (lipid$ adj2 emuls$).tw,kw.
26 (lipid$ adj2 formulation$).tw,kw.
27 (Lipid$ adj3 powder$).tw,kw.
28 (lipid adj3 spread$).tw,kw.
29 (lipid$ adj3 paste$).tw,kw.
30 (Nutributter$ or Plumpy$).tw,kw.
31 (LBNS$ or LNS$1 or iLiNS).tw,kw.
32 or/20‐31
33 19 or 32
34 infant/
35 (baby or babies or infant$ or toddler$ or child$).tw.
36 34 or 35
37 33 and 36
38 exp animals/ or exp invertebrate/ or animal experiment/ or animal model/ or animal tissue/ or animal cell/ or nonhuman/)
39 human/ or normal human/ or human cell/
40 38 not 39
41 37 not 40
42 exp erratum/
43 erratum.pt.
44 yes.nr.
45 tombstone.pt.
46 (comment or corrected or correction or corrigendum or "expression of concern" or erratum or retracted or retraction).ti.
47 or/42‐46
48 41 and 47

Retraction Watch Database retractiondatabase.org/RetractionSearch.aspx?

Searched 5 March 2019.

We searched for retractions of all reports of included studies using PubMed ID (where a PubMed ID existed for the report), and ran separate searches for the title of each paper. When searching by title alone retrieved a large number of records, we searched by a combination of title and surname of first author.

Cochrane Central Register of Controlled Trials (CENTRAL) in the Cochrane Library

#1[mh Lipids]
#2(fatty next acid*)
#3((Docosahexaenoic or Eicosapentaenoic) next acid*)
#4(PUFA or PUFAs)
#5lipid*
#6(omega next (3* or 6*))
#7(soy* or peanut or groundnut or whey or sesame or cashew or chickpea or oil*)
#8{or #1‐#7}
#9[mh "Dietary Supplements"]
#10[mh "Food, fortified"]
#11((diet* or food*) near/3 (fortif* or enrich* or supplement*))
#12(complement* near/3 (food* or feed*))
#13"Ready to use"
#14"point of use"
#15(RUSF or RUTF)
#16(home* near/2 fortif*)
#17{or #9‐#16}
#18#8 and #17
#19(lipid next based)
#20(lipid* near/3 supplement*)
#21(lipid* near/3 nutrient*)
#22(lipid* near/3 fortif*)
#23(lipid* near/3 formulation*)
#24(lipid* near/3 enrich*)
#25(lipid* near/3 emuls*)
#26(lipid* near/3 powder*)
#27(lipid* near/3 spread*)
#28(lipid* near/3 paste*)
#29(Nutributter* or Plumpy*)
#30(LNS or iLiNS)
#31{or #19‐#30}
#32#18 or #31
#33[mh ^Infant]
#34infant* or toddler* or baby or babies or child*
#35#33 or #34
#36#32 and #35 in Trials

MEDLINE Ovid

1 exp Lipids/
2 fatty acid$.tw,kf.
3 Docosahexaenoic acid.tw,kf.
4 Eicosapentaenoic Acid$.tw,kf.
5 PUFA$.tw,kf.
6 lipid.tw,kf.
7 (omega 3$ or omega 6$).tw,kf.
8 (soy$ or peanut or groundnut or whey or sesame or cashew or chickpea or oil$).tw,kf.
9 or/1‐8
10 Dietary Supplements/
11 Food, fortified/
12 ((diet$ or food$) adj3 (fortif$ or enrich$ or supplement$)).tw,kf.
13 (complement$ adj3 (food$ or feed$)).tw,kf.
14 "Ready to use".tw,kf.
15 (RUSF or RUTF).tw,kf.
16 "point of use".tw,kf.
17 (home$ adj2 fortif$).tw,kf.
18 or/10‐17
19 9 and 18
20 (lipid$ adj3 nutrient$).tw,kf.
21 (lipid$ adj3 supplement$).tw,kf.
22 lipid based.tw,kf.
23 (lipid$ adj3 fortif$).tw,kf.
24 (lipid$ adj3 enrich$).tw,kf.
25 (lipid$ adj2 emuls$).tw,kf.
26 (lipid$ adj2 formulation$).tw,kf.
27 (lipid$ adj3 powder$).tw,kf.
28 (lipid adj3 spread$).tw,kf.
29 (lipid$ adj3 paste$).tw,kf.
30 (Nutributter$ or Plumpy$).tw,kf.
31 (LBNS$ or LNS$1 or iLiNS).tw,kf.
32 or/20‐31
33 19 or 32
34 Infant/
35 (baby or babies or infant$ or toddler$ or child$).tw.
36 34 or 35
37 33 and 36
38 exp animals/ not humans.sh.
39 37 not 38

MEDLINE In‐Process and Other Non‐Indexed Citations Ovid

1 lipid based.tw,kf.
2 (lipid$ adj3 nutrient$).tw,kf.
3 (lipid$ adj3 supplement$).tw,kf.
4 (lipid$ adj3 fortif$).tw,kf.
5 (lipid$ adj3 enrich$).tw,kf.
6 (lipid$ adj2 emuls$).tw,kf.
7 (lipid$ adj2 formulation$).tw,kf.
8 (Lipid$ adj3 powder$).tw,kf.
9 (lipid adj3 spread$).tw,kf.
10 (lipid$ adj3 paste$).tw,kf.
11 (Nutributter$ or Plumpy$).tw,kf.
12 (LBNS$ or LNS$1 or iLiNS).tw,kf.
13 or/1‐12
14 ((diet$ or food$) adj3 (fortif$ or enrich$ or supplement$)).tw,kf.
15 (complement$ adj3 (food$ or feed$)).tw,kf.
16 (RUSF or RUTF).tw,kf.
17 "point of use".tw,kf.
18 (home$ adj2 fortif$).tw,kf.
19 lipid$.tw,kf.
20 fatty acid$.tw,kf.
21 Docosahexaenoic acid$.tw,kf.
22 Eicosapentaenoic Acid$.tw,kf.
23 PUFA$.tw,kf.
24 (omega 3$ or omega 6$).tw,kf.
25 (soy$ or peanut or groundnut or whey or sesame or cashew or chickpea or oil$).tw,kf.
26 or/14‐18
27 or/19‐25
28 26 and 27
29 13 or 28
30 (baby or babies or infant$ or toddler$ or child$).tw.
31 29 and 30

MEDLINE E‐pub ahead of print Ovid

1 lipid based.tw,kf.
2 (lipid$ adj3 nutrient$).tw,kf.
3 (lipid$ adj3 supplement$).tw,kf.
4 (lipid$ adj3 fortif$).tw,kf.
5 (lipid$ adj3 enrich$).tw,kf.
6 (lipid$ adj2 emuls$).tw,kf.
7 (lipid$ adj2 formulation$).tw,kf.
8 (Lipid$ adj3 powder$).tw,kf.
9 (lipid adj3 spread$).tw,kf.
10 (lipid$ adj3 paste$).tw,kf.
11 (Nutributter$ or Plumpy$).tw,kf.
12 (LBNS$ or LNS$1 or iLiNS).tw,kf.
13 or/1‐12
14 ((diet$ or food$) adj3 (fortif$ or enrich$ or supplement$)).tw,kf.
15 (complement$ adj3 (food$ or feed$)).tw,kf.
16 (RUSF or RUTF).tw,kf.
17 "point of use".tw,kf.
18 (home$ adj2 fortif$).tw,kf.
19 lipid$.tw,kf.
20 fatty acid$.tw,kf.
21 Docosahexaenoic acid$.tw,kf.
22 Eicosapentaenoic Acid$.tw,kf.
23 PUFA$.tw,kf.
24 (omega 3$ or omega 6$).tw,kf.
25 (soy$ or peanut or groundnut or whey or sesame or cashew or chickpea or oil$).tw,kf.
26 or/14‐18
27 or/19‐25
28 26 and 27
29 13 or 28
30 (baby or babies or infant$ or toddler$ or child$).tw.
31 29 and 30

Embase Ovid

1 exp Lipids/
2 fatty acid$.tw,kw.
3 Docosahexaenoic acid.tw,kw.
4 Eicosapentaenoic Acid$.tw,kw.
5 PUFA$.tw,kw.
6 lipid$.tw,kw.
7 (omega 3$ or omega 6$).tw,kw.
8 (soy$ or peanut or groundnut or whey or sesame or cashew or chickpea or oil$).tw,kw.
9 or/1‐8
10 dietary supplement/
11 fortified food/
12 ((diet$ or food$) adj3 (fortif$ or enrich$ or supplement$)).tw,kw.
13 (complement$ adj3 (food$ or feed$)).tw,kw.
14 "Ready to use".tw,kw.
15 (RUSF or RUTF).tw,kw.
16 "point of use".tw,kw.
17 (home$ adj2 fortif$).tw,kw.
18 or/10‐17
19 9 and 18
20 lipid based.tw,kw.
21 (lipid$ adj3 nutrient$).tw,kw.
22 (lipid$ adj3 supplement$).tw,kw.
23 (lipid$ adj3 fortif$).tw,kw.
24 (lipid$ adj3 enrich$).tw,kw.
25 (lipid$ adj2 emuls$).tw,kw.
26 (lipid$ adj2 formulation$).tw,kw.
27 (Lipid$ adj3 powder$).tw,kw.
28 (lipid adj3 spread$).tw,kw.
29 (lipid$ adj3 paste$).tw,kw.
30 (Nutributter$ or Plumpy$).tw,kw.
31 (LBNS$ or LNS$1 or iLiNS).tw,kw.
32 or/20‐31
33 19 or 32
34 infant/
35 (baby or babies or infant$ or toddler$ or child$).tw.
36 34 or 35
37 33 and 36
38 exp animals/ or exp invertebrate/ or animal experiment/ or animal model/ or animal tissue/ or animal cell/ or nonhuman/
39 human/ or normal human/ or human cell/
40 38 not 39
41 37 not 40

CINAHL Plus EBSCOhost (Cumulative Index to Nursing and Allied Health Literature

S1(MH "Lipids+")
S2TI (lipid*) or AB (lipid*)
S3TI(Docosahexaenoic acid*) OR AB(Docosahexaenoic acid*)
S4TI( Eicosapentaenoic acid*) OR AB( Eicosapentaenoic acid*)
S5TI(PUFA*) OR AB(PUFA* )
S6TI(omega 3* or omega 6*) OR AB(omega 3* or omega 6* )
S7TI (soy* or peanut or groundnut or whey or sesame or cashew or chickpea or oil*) or AB(soy* or peanut or groundnut or whey or sesame or cashew or chickpea or oil*)
S8TI(fatty acid*) OR AB(fatty acid* )
S9S1 OR S2 OR S3 OR S4 OR S5 OR S6 OR S7 OR S8
S10(MH "Dietary Supplements")
S11(MH "Dietary Supplementation")
S12(MH "Food, Fortified")
S13TI ((diet* or food*) n3 (fortif* or enrich* or supplement*)) OR AB((diet* or food*) n3 (fortif* or enrich* or supplement*))
S14TI (complement* N3 (food* or feed*)) or AB (complement* N3 (food* or feed*))
S15"Ready to use"
S16(RUSF or RUTF)
S17"point of use"
S18TI (home* N2 fortif*) OR AB(home* N2 fortif*)
S19S10 OR S11 OR S12 OR S13 OR S14 OR S15 OR S16 OR S17 OR S18
S20S9 AND S19
S21TI (lipid based) or AB (lipid based)
S22TI(lipid* N3 supplement*) OR AB( lipid* N3 supplement*)
S23TI(lipid* N3 nutrient*) OR AB(lipid* N3 nutrient*)
S24TI(lipid* N3 fortif*) OR AB (lipid* N3 fortif*)
S25TI(lipid* N3 formulation*) OR AB(lipid* N3 formulation*)
S26TI(lipid* N3 enrich*) OR AB(lipid* N3 enrich* )
S27TI(lipid* N3 emuls*) OR AB(lipid* N3 emuls*)
S28TI(lipid* N3 powder*) OR AB(lipid* N3 powder*)
S29TI(lipid N3 spread*) OR AB(lipid N3 spread*)
S30TI(lipid* N3 paste*) OR AB(lipid* N3 paste*)
S31Nutributter*
S32 Plumpy*
S33TI(LNS*1 or iLiNS) OR AB( LNS*1 or iLiNS)
S34S21 OR S22 OR S23 OR S24 OR S25 OR S26 OR S27 OR S28 OR S29 OR S30 OR S31 OR S32 OR S33
S35S20 OR S34
S36(MH "Infant")
S37TI(baby or babies or infant* or toddler* or child*) OR AB (baby or babies or infant* or toddler* or child*)
S38S36 OR S37
S39S35 AND S38

Science Citation Index (SCI) and Social Sciences Citation Index (SSCI) Web of Science

#5 #4 AND #3
#4 TS=(infant* OR child* OR toddler* or baby or babies)
#3 #2 OR #1
#2 TS=(Nutributter* OR Plumpy* OR LNS OR iLiNS OR "lipid based" )
#1 TS=(( "fatty acid*" OR PUFA OR PUFAs OR "omega 3*" OR "omega 6*" OR soy* OR peanut* OR groundnut* OR whey* OR sesame* OR cashew* OR chickpea* OR oil* ) Near/3 ( FORTIF* OR ENRICH OR SUPPLEMENT* OR "READY TO USE" OR "POINT OF USE" OR RUSF OR RUTF OR PASTE* OR SPREAD* OR FORMULAT* OR EMULS* OR NUTRIENT* OR POWDER*))

Conference Proceedings Citation Index ‐ Science (CPCI‐S) and Conference Proceedings Citation Index ‐ Social Science & Humanities (CPCI‐SS&H) Web of Science

#5 #4 AND #3
DocType=All document types; Language=All languages;
#4 TS=(infant* OR child* OR toddler* or baby or babies)
DocType=All document types; Language=All languages;
#3 #2 OR #1
DocType=All document types; Language=All languages;
#2 TS=(Nutributter* OR Plumpy* OR LNS OR iLiNS OR "lipid based" )
DocType=All document types; Language=All languages;
#1 TS=(( "fatty acid*" OR PUFA OR PUFAs OR "omega 3*" OR "omega 6*" OR soy* OR peanut* OR groundnut* OR whey* OR sesame* OR cashew* OR chickpea* OR oil* ) Near/3 ( FORTIF* OR ENRICH OR SUPPLEMENT* OR "READY TO USE" OR "POINT OF USE" OR RUSF OR RUTF OR PASTE* OR SPREAD* OR FORMULAT* OR EMULS* OR NUTRIENT* OR POWDER*))
DocType=All document types; Language=All languages;

Cochrane Database of Systematic Reviews (CDSR), part of the Cochrane Library

#1[mh Lipids]
#3((Docosahexaenoic or Eicosapentaenoic) next acid*):ti,ab
#4(PUFA or PUFAs):ti,ab
#5lipid*:ti,ab 23529
#6(omega next (3* or 6*)):ti,ab
#7(soy* or peanut or groundnut or whey or sesame or cashew or chickpea or oil*):ti,ab
#8{or #1‐#7}
#9[mh "Dietary Supplements"]
#10[mh "Food, fortified"]
#11((diet* or food*) near/3 (fortif* or enrich* or supplement*)):ti,ab
#12(complement* near/3 (food* or feed*)):ti,ab
#13"Ready to use":ti,ab
#14"point of use":ti,ab
#15(RUSF or RUTF):ti,ab
#16(home* near/2 fortif*):ti,ab
#17{or #9‐#16}
#18#8 and #17
#19(lipid next based):ti,ab
#20(lipid* near/3 supplement*):ti,ab
#21(lipid* near/3 nutrient*):ti,ab
#22(lipid* near/3 fortif*):ti,ab
#23(lipid* near/3 formulation*):ti,ab
#24(lipid* near/3 enrich*):ti,ab
#25(lipid* near/3 emuls*):ti,ab
#26(lipid* near/3 powder*):ti,ab
#27(lipid* near/3 spread*):ti,ab
#28(lipid* near/3 paste*):ti,ab
#29(Nutributter* or Plumpy*):ti,ab
#30(LNS*1 or iLiNS):ti,ab
#31{or #19‐#30}
#32#18 or #31
#33[mh ^Infant]
#34infant* or toddler* or baby or babies or child*:ti,ab
#35#33 or #34
#36#32 and #35 in Cochrane Reviews (Reviews and Protocols)

Database of Abstracts of Reviews of Effect (DARE), part of the Cochrane Library

#1[mh Lipids]
#3((Docosahexaenoic or Eicosapentaenoic) next acid*):ti,ab
#4(PUFA or PUFAs):ti,ab
#5lipid*:ti,ab 23529
#6(omega next (3* or 6*)):ti,ab
#7(soy* or peanut or groundnut or whey or sesame or cashew or chickpea or oil*):ti,ab
#8{or #1‐#7}
#9[mh "Dietary Supplements"]
#10[mh "Food, fortified"]
#11((diet* or food*) near/3 (fortif* or enrich* or supplement*)):ti,ab
#12(complement* near/3 (food* or feed*)):ti,ab
#13"Ready to use":ti,ab
#14"point of use":ti,ab
#15(RUSF or RUTF):ti,ab
#16(home* near/2 fortif*):ti,ab
#17{or #9‐#16}
#18#8 and #17
#19(lipid next based):ti,ab
#20(lipid* near/3 supplement*):ti,ab
#21(lipid* near/3 nutrient*):ti,ab
#22(lipid* near/3 fortif*):ti,ab
#23(lipid* near/3 formulation*):ti,ab
#24(lipid* near/3 enrich*):ti,ab
#25(lipid* near/3 emuls*):ti,ab
#26(lipid* near/3 powder*):ti,ab
#27(lipid* near/3 spread*):ti,ab
#28(lipid* near/3 paste*):ti,ab
#29(Nutributter* or Plumpy*):ti,ab
#30(LNS*1 or iLiNS):ti,ab
#31{or #19‐#30}
#32#18 or #31
#33[mh ^Infant]
#34infant* or toddler* or baby or babies or child*:ti,ab
#35#33 or #34
#36#32 and #35 in Other Reviews

Epistemonikos (epistemonikos.org)

(title:(LIPID* OR FATTY ACID* OR OMEGA OR Docosahexaenoic OR Eicosapentaenoic OR soy* OR peanut OR groundnut OR whey OR sesame OR cashew OR chickpea OR oil*) OR abstract:(LIPID* OR FATTY ACID* OR OMEGA OR Docosahexaenoic OR Eicosapentaenoic OR soy* OR peanut OR groundnut OR whey OR sesame OR cashew OR chickpea OR oil*)) AND (title:(fortif* OR enrich* OR supplement* OR "Ready to use" OR "point of use" OR RUSF OR RUTF) OR abstract:(fortif* OR enrich* OR supplement* OR "Ready to use" OR "point of use" OR RUSF OR RUTF)) AND title:(babies OR children OR infant*)

LIMITED TO

PUBLICATION TYPE: SYSTEMATIC REVIEW
SYSTEMATIC REVIEW QUESTION : INTERVENTIONS

POPLINE (www.popline.org)

((ALL FIELDS(lipid* OR "fatty acid*" OR PUFA OR PUFAs OR "omega 3*" OR "omega 6*" OR soy* OR peanut* OR groundnut* OR whey* OR sesame* OR cashew* OR chickpea* OR oil*) AND ALL FIELDS (FORTIF* OR ENRICH OR SUPPLEMENT* OR "READY TO USE" OR "POINT OF USE" OR RUSF OR RUTF OR PASTE* OR SPREAD* OR FORMULAT* OR EMULS* OR NUTRIENT* OR POWDER*)) OR (Nutributter* OR Plumpy* OR LNS OR iLiNS)) AND ALL FIELDS (infan* OR child* OR baby OR babies OR toddler*)

ClinicalTrials.gov (clinicaltrials.gov)

Interventional Studies | LIPID‐BASED OR LNS OR iLiNS OR "NUTRIENT SUPPLEMENT" OR PASTE OR SPREAD OR BLEND OR NUTRIBUTTER OR Plumpy OR PLUMPYNUT | Child

World Health Organization International Clinical Trials Registry Platform (WHO ICTRP; who.int/trialsearch)

(LIPID BASED OR LNS OR iLiNS OR NUTRIENT SUPPLEMENT OR SPREAD OR paste OR BLEND OR NUTRIBUTTER OR Plumpy OR PLUMPYNUT) NOT (teeth OR oral heath OR dentistry)

IBECS (Índice Bibliográfico Español en Ciencias de la Salud; ibecs.isciii.es)

WORD| "lipid based" OR LNS OR iLiNS OR "nutrient supplement" OR paste OR spread OR blend OR nutributter OR Plumpy OR plumpynut

AND

WORD| infan* OR child* OR baby OR babies OR toddler*

SciELO (Scientific Electronic Library Online; www.scielo.br)

"lipid based" OR LNS OR iLiNS OR "nutrient supplement" OR paste OR spread OR blend OR nutributter OR Plumpy OR plumpynut [All indexes]

AND

infan* OR child* OR baby OR babies OR toddler* [All indexes]

AIM (Africa Index Medicus; search.bvsalud.org/ghl/?lang=en&submit=Search&where=REGIONAL)

(lipid based OR LNS OR iLiNS OR nutrient supplement OR paste OR spread OR blend OR nutributter OR Plumpy OR plumpynut) AND (infan OR child OR baby OR babies OR toddler)

IMEMR (Index Medicus for the Eastern Mediterranean Region; search.bvsalud.org/ghl/?lang=en&submit=Search&where=REGIONAL)

(lipid based OR LNS OR iLiNS OR nutrient supplement OR paste OR spread OR blend OR nutributter OR Plumpy OR plumpynut) [Title]

AND

(infan OR child OR baby OR babies OR toddler) [Title]

LILACS (Latin American and Caribbean Health Sciences Literature; lilacs.bvsalud.org/en)

(tw:("lipid based" OR LNS OR iLiNS OR "nutrient supplement" OR paste OR spread OR blend OR nutributter OR Plumpy OR plumpynut) AND (tw:(infan* OR child* OR baby OR babies OR toddler*)

PAHO/WHO Institutional Repository for Information Sharing (iris.paho.org/xmlui)

("lipid based" OR LNS OR iLiNS OR "nutrient supplement" OR paste OR spread OR blend OR nutributter OR Plumpy OR plumpynut) AND (infan* OR child* OR baby OR babies OR toddler*)

WHOLIS (WHO Library Database; search.bvsalud.org/ghl/?lang=en&submit=Search&where=REGIONAL)

words or phrase "lipid based" OR LNS OR iLiNS OR "nutrient supplement" OR paste OR spread OR blend OR nutributter OR Plumpy OR plumpynut AND words or phrase infan* OR child* OR baby OR babies OR toddler*

WPRIM (Western Pacific Index Medicus; search.bvsalud.org/ghl/?lang=en&submit=Search&where=REGIONAL)

("lipid based" OR LNS OR iLiNS OR "nutrient supplement" OR paste OR spread OR blend OR nutributter OR Plumpy OR plumpynut) AND (infan* OR child* OR baby OR babies OR toddler*)

IMSEAR (Index Medicus for the South‐East Asian Region; search.bvsalud.org/ghl/?lang=en&submit=Search&where=REGIONAL)

("lipid based" OR LNS OR iLiNS OR "nutrient supplement" OR paste OR spread OR blend OR nutributter OR Plumpy OR plumpynut) [Title] AND (infan* OR child* OR baby OR babies OR toddler*) [Title]

IndMED (indmed.nic.in/indmed.html)

(lipid based OR LNS OR iLiNS OR nutrient supplement OR paste OR spread OR blend OR nutributter OR Plumpy OR plumpynut) AND (infan OR child OR baby OR babies OR toddler)

Native Health Research Database (hscssl.unm.edu/nhd)

Keywords: (Supplement AND child)

Random sequence generation (checking for possible selection bias)

We assessed whether the method used to generate the allocation sequence was described in sufficient detail to allow an assessment of whether it produced comparable groups.

1. Low risk of bias: any truly random process (for example, random number table, computer random number generator)

2. High risk of bias: any non‐random process (for example, odd or even date of birth, hospital or clinic record number)

3. Unclear risk of bias: insufficient information provided to permit judgement of high or low risk of bias

Allocation concealment (checking for possible selection bias)

We assessed whether the method used to conceal the allocation sequence was described in sufficient detail to determine whether intervention allocations could have been foreseen in advance of, or during, enrolment.

1. Low risk of bias: telephone or central randomisation; consecutively numbered, sealed, opaque envelopes

2. High risk of bias: open random allocation, unsealed or non‐opaque envelopes

3. Unclear risk of bias: insufficient information provided to permit judgement of high or low risk of bias

Blinding of participants and personnel (checking for possible performance bias)

We described all measures used, if any, to blind study participants and personnel from knowledge of which intervention a participant received.

We assessed the risk of performance bias associated with blinding of participants and personnel as follows.

1. Low risk of bias: blinding of participants and personnel and unlikely that the blinding could have been broken, or no blinding or incomplete blinding but outcome unlikely to have been influenced

2. High risk of bias: participants and personnel not blinded, incomplete or broken blinding and outcome likely to have been influenced

3. Unclear risk of bias: insufficient information provided to permit judgement of high or low risk of bias

Whilst assessed separately, we combined the results into a single evaluation of risk of bias associated with blinding (Higgins 2011a).

Blinding of outcome assessment (checking for possible detection bias)

We described all measures used, if any, to blind outcome assessors from knowledge of which intervention a participant received.

1. Low risk of bias: blinding of outcome assessment and unlikely that the blinding could have been broken, or no blinding but measurement unlikely to have been influenced

2. High risk of bias: no blinding of outcome assessment, measurement likely to have been influenced by lack of blinding, or blinding could have been broken

3. Unclear risk of bias: insufficient information provided to permit judgement of high or low risk of bias

Incomplete outcome data (checking for possible attrition bias through withdrawals, dropouts, protocol deviations)

We assessed the outcomes in each included study as follows.

1. Low risk of bias: no missing outcome data or missing outcome data were unlikely to bias the results based on the following considerations; study authors provided transparent documentation of participant flow throughout the study, the proportion of missing data was similar in the intervention and control groups, the reasons for missing data were provided and balanced across intervention and control groups, or the reasons for missing data were not likely to bias the results (for example, moving house)

2. High risk of bias: missing outcome data were likely to bias the result, 'as‐treated (per protocol)' analysis was performed with substantial differences between the intervention received and that assigned at randomisation, or potentially inappropriate methods for imputation were used

3. Unclear risk of bias: insufficient information provided to permit judgement of high or low risk of bias

Selective outcome reporting (checking for possible reporting bias)

Selective reporting can lead to reporting bias. We compared the methods to the results and looked for outcomes that were measured (or likely to have been measured) but not reported.

1. Low risk of bias: all of the study’s pre‐specified outcomes and expected outcomes of interest to the review were reported

2. High risk of bias: not all of the study’s pre‐specified outcomes were reported, one or more reported primary outcomes were not pre‐specified, outcomes of interest were reported incompletely and so could not be used, or the study failed to include the results of a key outcome that was expected to be reported

3. Unclear risk of bias: insufficient information provided to permit judgement of high or low risk of bias

Other sources of bias (checking for other possible sources of bias not covered by the domains above)

We assessed if the study was free of other potential bias as follows.

1. Low risk of bias: similarity between outcome measures at baseline, similarity between potential confounding variables at baseline, or adequate protection of study arms against contamination

2. High risk of bias: no similarity between outcome measures at baseline, no similarity between potential confounding variables at baseline, or inadequate protection of study arms against contamination

3. Unclear risk of bias: insufficient information provided to permit judgement of high or low risk of bias