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Risk of bias summary: Review authors' judgements about each risk of bias item for each included study.
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Figure 1

Risk of bias summary: Review authors' judgements about each risk of bias item for each included study.

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Study flow diagram.
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Figure 2

Study flow diagram.

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Comparison 1 Fermented milk versus placebo, Outcome 1 Systolic blood pressure.
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Analysis 1.1

Comparison 1 Fermented milk versus placebo, Outcome 1 Systolic blood pressure.

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Comparison 1 Fermented milk versus placebo, Outcome 2 Length of intervention period SBP.
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Analysis 1.2

Comparison 1 Fermented milk versus placebo, Outcome 2 Length of intervention period SBP.

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Comparison 1 Fermented milk versus placebo, Outcome 3 Baseline SBP high versus low SBP.
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Analysis 1.3

Comparison 1 Fermented milk versus placebo, Outcome 3 Baseline SBP high versus low SBP.

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Comparison 1 Fermented milk versus placebo, Outcome 4 Antihypertensive medication SBP.
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Analysis 1.4

Comparison 1 Fermented milk versus placebo, Outcome 4 Antihypertensive medication SBP.

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Comparison 1 Fermented milk versus placebo, Outcome 5 Diastolic blood pressure.
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Analysis 1.5

Comparison 1 Fermented milk versus placebo, Outcome 5 Diastolic blood pressure.

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Comparison 1 Fermented milk versus placebo, Outcome 6 Length of intervention group DBP.
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Analysis 1.6

Comparison 1 Fermented milk versus placebo, Outcome 6 Length of intervention group DBP.

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Comparison 1 Fermented milk versus placebo, Outcome 7 Baseline SBP high versus low DBP.
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Analysis 1.7

Comparison 1 Fermented milk versus placebo, Outcome 7 Baseline SBP high versus low DBP.

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Comparison 1 Fermented milk versus placebo, Outcome 8 Anthypertensive medication DBP.
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Analysis 1.8

Comparison 1 Fermented milk versus placebo, Outcome 8 Anthypertensive medication DBP.

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Comparison 2 24hBP, Outcome 1 SBP.
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Analysis 2.1

Comparison 2 24hBP, Outcome 1 SBP.

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Comparison 2 24hBP, Outcome 2 DBP.
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Analysis 2.2

Comparison 2 24hBP, Outcome 2 DBP.

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Comparison 1. Fermented milk versus placebo

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Systolic blood pressure Show forest plot

15

1232

Mean Difference (IV, Random, 95% CI)

‐2.45 [‐4.30, ‐0.60]

2 Length of intervention period SBP Show forest plot

15

1232

Mean Difference (IV, Random, 95% CI)

‐2.45 [‐4.30, ‐0.60]

2.1 intervention 4‐8 weeks

9

780

Mean Difference (IV, Random, 95% CI)

‐2.26 [‐4.37, ‐0.15]

2.2 Intervention longer than 8 weeks

6

452

Mean Difference (IV, Random, 95% CI)

‐3.02 [‐7.16, 1.13]

3 Baseline SBP high versus low SBP Show forest plot

15

1232

Mean Difference (IV, Random, 95% CI)

‐2.45 [‐4.30, ‐0.60]

3.1 Baseline SBP above 140

11

881

Mean Difference (IV, Random, 95% CI)

‐2.31 [‐5.10, 0.47]

3.2 Baseline SBP below 140

5

351

Mean Difference (IV, Random, 95% CI)

‐3.28 [‐4.51, ‐2.04]

4 Antihypertensive medication SBP Show forest plot

15

1232

Mean Difference (IV, Random, 95% CI)

‐2.45 [‐4.30, ‐0.60]

4.1 No antihypertensive medication allowed

13

1163

Mean Difference (IV, Random, 95% CI)

‐2.08 [‐3.98, ‐0.18]

4.2 Antihypertensive medication allowed

2

69

Mean Difference (IV, Random, 95% CI)

‐7.37 [‐13.06, ‐1.69]

5 Diastolic blood pressure Show forest plot

15

1232

Mean Difference (IV, Random, 95% CI)

‐0.67 [‐1.48, 0.14]

6 Length of intervention group DBP Show forest plot

15

1232

Mean Difference (IV, Random, 95% CI)

‐0.67 [‐1.48, 0.14]

6.1 Intervention 4‐8 weeks

9

780

Mean Difference (IV, Random, 95% CI)

‐0.66 [‐1.60, 0.28]

6.2 Intervention longer than 8 weeks

6

452

Mean Difference (IV, Random, 95% CI)

‐0.56 [‐2.35, 1.23]

7 Baseline SBP high versus low DBP Show forest plot

15

1232

Mean Difference (IV, Random, 95% CI)

‐0.67 [‐1.48, 0.14]

7.1 Baseline SBP above 140 DBP

11

881

Mean Difference (IV, Random, 95% CI)

‐0.31 [‐1.26, 0.64]

7.2 Baseline SBP below 140 DBP

5

351

Mean Difference (IV, Random, 95% CI)

‐1.42 [‐2.40, ‐0.44]

8 Anthypertensive medication DBP Show forest plot

15

1232

Mean Difference (IV, Random, 95% CI)

‐0.67 [‐1.48, 0.14]

8.1 No antihypertensive medication allowed

13

1163

Mean Difference (IV, Random, 95% CI)

‐0.50 [‐1.30, 0.29]

8.2 Antihypertensive medication allowed

2

69

Mean Difference (IV, Random, 95% CI)

‐3.98 [‐7.37, ‐0.60]
Figuras y tablas -
Comparison 1. Fermented milk versus placebo
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Comparison 2. 24hBP

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 SBP Show forest plot

6

Mean Difference (Random, 95% CI)

‐0.80 [‐2.72, 1.12]

2 DBP Show forest plot

5

Mean Difference (Random, 95% CI)

‐0.74 [‐1.67, 0.20]
Figuras y tablas -
Comparison 2. 24hBP
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