Source

Search strategy

Hits retrieved

1. ALOIS (www.medicine.ox.ac.uk/alois)

driving OR car OR cars OR driver OR drivers OR automobile OR vehicle

20

2. MEDLINE In‐process and other non‐indexed citations and MEDLINE 1950‐present (Ovid SP)

1. exp Dementia/

2. Delirium/

3. Wernicke Encephalopathy/

4. Delirium, Dementia, Amnestic, Cognitive Disorders/

5. dement*.mp.

6. alzheimer*.mp.

7. (lewy* adj2 bod*).mp.

8. deliri*.mp.

9. (chronic adj2 cerebrovascular).mp.

10. ("organic brain disease" or "organic brain syndrome").mp.

11. ("normal pressure hydrocephalus" and "shunt*").mp.

12. "benign senescent forgetfulness".mp.

13. (cerebr* adj2 deteriorat*).mp.

14. (cerebral* adj2 insufficient*).mp.

15. (pick* adj2 disease).mp.

16. (creutzfeldt or jcd or cjd).mp.

17. huntington*.mp.

18. binswanger*.mp.

19. korsako*.mp.

20. or/1‐19

21. (motor adj2 vehicle*).ti,ab.

22. (automobile adj2 driving).ti,ab.

23. (automobile adj2 driver*).ti,ab.

24. (car adj2 driver*).ti,ab.

25. (traffic adj2 accident*).ti,ab.

26. (car adj2 accident*).ti,ab.

27. Accidents, Traffic/ or Automobile Driving/

28. (driving and (asess* or continu* or capabilit*)).ti,ab.

29. or/21‐28

30. 20 and 29

31. randomized controlled trial.pt.

32. controlled clinical trial.pt.

33. randomized.ab.

34. placebo.ab.

35. randomly.ab.

36. trial.ab.

37. groups.ab.

38. or/31‐37

39. 30 and 38

40. (2007* or 2008* or 2009* or 2010* or 2011* or 2012*).ed.

41. 39 and 40

21

3. EMBASE

1974‐2012 September 07 (Ovid SP)

1. exp dementia/

2. Lewy body/

3. delirium/

4. Wernicke encephalopathy/

5. cognitive defect/

6. dement*.mp.

7. alzheimer*.mp.

8. (lewy* adj2 bod*).mp.

9. deliri*.mp.

10. (chronic adj2 cerebrovascular).mp.

11. ("organic brain disease" or "organic brain syndrome").mp.

12. "supranuclear palsy".mp.

13. ("normal pressure hydrocephalus" and "shunt*").mp.

14. "benign senescent forgetfulness".mp.

15. (cerebr* adj2 deteriorat*).mp.

16. (cerebral* adj2 insufficient*).mp.

17. (pick* adj2 disease).mp.

18. (creutzfeldt or jcd or cjd).mp.

19. huntington*.mp.

20. binswanger*.mp.

21. korsako*.mp.

22. CADASIL.mp.

23. or/1‐22

24. (motor adj2 vehicle*).ti,ab.

25. (automobile adj2 driving).ti,ab.

26. (automobile adj2 driver*).ti,ab.

27. (car adj2 driver*).ti,ab.

28. (traffic adj2 accident*).ti,ab.

29. (car adj2 accident*).ti,ab.

30. (driving and (asess* or continu* or capabilit* or evaluat*)).ti,ab.

31. car driving/ or driving ability/ or traffic accident/

32. or/24‐31

33. 23 and 32

34. randomized controlled trial/

35. controlled clinical trial/

36. placebo.ab.

37. trial.ti,ab.

38. randomly.ab.

39. groups.ab.

40. (RCT or CCT).ti,ab.

41. randomi?ed.ab.

42. or/34‐41

43. 33 and 42

44. (2007* or 2008* or 2009* or 2010* or 2011* or 2012*).em.

45. 43 and 44

97

4. PsycINFO

1806‐July week 1 2012 (Ovid SP)

1. exp Dementia/

2. exp Delirium/

3. exp Huntingtons Disease/

4. exp Kluver Bucy Syndrome/

5. exp Wernickes Syndrome/

6. exp Cognitive Impairment/

7. dement*.mp.

8. alzheimer*.mp.

9. (lewy* adj2 bod*).mp.

10. deliri*.mp.

11. (chronic adj2 cerebrovascular).mp.

12. ("organic brain disease" or "organic brain syndrome").mp.

13. "supranuclear palsy".mp.

14. ("normal pressure hydrocephalus" and "shunt*").mp.

15. "benign senescent forgetfulness".mp.

16. (cerebr* adj2 deteriorat*).mp.

17. (cerebral* adj2 insufficient*).mp.

18. (pick* adj2 disease).mp.

19. (creutzfeldt or jcd or cjd).mp.

20. huntington*.mp.

21. binswanger*.mp.

22. korsako*.mp.

23. ("parkinson* disease dementia" or PDD or "parkinson* dementia").mp.

24. or/1‐23

25. (motor adj2 vehicle*).ti,ab.

26. (automobile adj2 driving).ti,ab.

27. (automobile adj2 driver*).ti,ab.

28. (car adj2 driver*).ti,ab.

29. (traffic adj2 accident*).ti,ab.

30. (car adj2 accident*).ti,ab.

31. (driving and (asess* or continu* or capabilit* or evaluat*)).ti,ab.

32. exp Driving Behavior/ or exp Motor Vehicles/

33. or/25‐32

34. 24 and 33

35. (2007* or 2008* or 2009* or 2010* or 2011* or 2012*).up.

36. 34 and 35

37. randomi?ed.ab.

38. exp Clinical Trials/

39. randomly.ab.

40. (RCT or CCT).ti,ab.

41. groups.ab.

42. ("double‐blind*" or "single‐blind*").ti,ab.

43. placebo.ab.

44. trial.ti,ab.

45. or/37‐44

46. 36 and 45

24

5. CINAHL (EBSCOhost)

S1 (MH "Dementia+")

S2 (MH "Delirium") or (MH "Delirium, Dementia, Amnestic, Cognitive Disorders") 

S3 (MH "Wernicke's Encephalopathy") 

S4 TX dement*

S5 TX alzheimer* 

S6 TX lewy* N2 bod* 

S7 TX deliri* 

S8 TX chronic N2 cerebrovascular

S9 TX "organic brain disease" or "organic brain syndrome" 

S10 TX "normal pressure hydrocephalus" and "shunt*"

S11 TX "benign senescent forgetfulness"

S12 TX cerebr* N2 deteriorat* 

S13 TX cerebral* N2 insufficient* 

S14 TX pick* N2 disease 

S15 TX creutzfeldt or jcd or cjd 

S16 TX huntington* 

S17 TX binswanger*

S18 TX korsako* 

S19 S1 or S2 or S3 or S4 or S5 or S6 or S7 or S8 or S9 or S10 or S11 or S12 or S13 or S14 or S15 or S16 or S17 or S18 

S20 (MH "Automobile Driving") OR (MH "Drive") OR (MH "Automobile Driver Examination") 

S21 TX motor N2 vehicle* 

S22 TX automobile N2 driving 

S23 TX automobile adj2 driver* 

S24 TX car N2 driver*

S25 TX traffic N2 accident* 

S26 TX car N2 accident* 

S27 TX driving N3 asess*

S28 TX driving N3 continu* 

S29 TX driving N3 capabilit*

S30 TX driving N3 evaluat* 

S31 S20 or S21 or S22 or S23 or S24 or S25 or S26 or S27 or S28 or S29 or S30 

S32 S19 and S31 

S33 EM 2007

S34 EM 2008

S35 EM 2009

S36 EM 2010

S37 EM 2011

S38 EM 2012

S39 S33 or S34 or S35 or S36 or S37 or S38 

S40 S32 and S39 

144

6. Web of Science and conference proceedings

Topic=(dement* OR VCI OR "vascular cognitive impairment*" OR VaD OR alzheimer* OR AD) AND Topic=(driving OR car OR vehicle* OR cars OR automobile) AND Year Published=(2007‐2012) AND Topic=(randomly OR trial OR randomised OR randomized OR RCT OR "control* study" OR CCT OR placebo)

Timespan=All Years. Databases=SCI‐EXPANDED, SSCI, A&HCI, CPCI‐S, CPCI‐SSH.

Lemmatization=On  

353

7. LILACS (BIREME)

conducción OR driving OR condução OR car OR vehicle OR carro OR coche OR vehículo OR veículo [Words] and dementia OR demencia OR demência OR alzheimer OR alzheimers OR alzheimer’s [Words]

16

8. CENTRAL (The Cochrane Library) (Issue 2 of 4, 2012)

#1 dement*

#2 alzheimer*

#3 deliri*

#4 chronic adj2 cerebrovascular

#5 (lewy* bod*)

#6 "organic brain disease" or "organic brain syndrome"

#7 (pick* disease)

#8 creutzfeldt or jcd or cjd

#9 huntington*

#10 binswanger*

#11 korsako*

#12 (#1 OR #2 OR #3 OR #4 OR #5 OR #6 OR #7 OR #8 OR #9 OR #10 OR #11)

#13 driving OR driver OR drivers OR car OR vehicle OR automobile

#14 MeSH descriptor Automobile Driving explode all trees

#15 (#13 OR #14)

#16 (#12 AND #15), from 2007 to 2012

34

9. Clinicaltrials.gov (www.clinicaltrials.gov)

driving OR car OR vehicle OR driver OR drive | Interventional Studies | dementia OR alzheimers OR AD OR alzheimer's OR alzheimer OR lewy OR FTLD OR FLD OR MCI OR cognitive OR cognition | received from 10/01/2007 to 09/09/2012

32

10. ICTRP Search Portal (apps.who.int/trialsearch) (includes: Australian New Zealand Clinical Trials Registry; ClinicalTrilas.gov; ISRCTN; Chinese Clinical Trial Registry; Clinical Trials Registry – India; Clinical Research Information Service – Republic of Korea; German Clinical Trials Register; Iranian Registry of Clinical Trials; Japan Primary Registries Network; Pan African Clinical Trial Registry; Sri Lanka Clinical Trials Registry; The Netherlands National Trial Register)

(dementia OR alzheimers OR AD OR alzheimer's OR alzheimer OR lewy OR FTLD OR FLD OR MCI OR cognitive OR cognition) AND (driving OR driver) AND (2007‐2012)

0

TOTAL before de‐duplication and first assess

741

TOTAL after de‐duplication and first assess

122