The Cochrane Skin Group made the decision to allow another team to incorporate the subject of this review into the protocol that they were writing in order to update another review that has been out of date for some years. We feel it makes clinical sense to combine these two reviews.

This review is being withdrawn as it has been updated by incorporation into another broader Cochrane review 'Systemic treatments for metastatic cutaneous melanoma'. The citation for the new review is as follows: Pasquali S, Hadjinicolaou AV, Chiarion Sileni V, Rossi CR, Mocellin S. Systemic treatments for metastatic cutaneous melanoma. Cochrane Database of Systematic Reviews 2018, Issue 2. Art. No.: CD011123. DOI: 10.1002/14651858.CD011123.pub2.

The editorial group responsible for this previously published document have withdrawn it from publication.