Scolaris Content Display Scolaris Content Display

Cochrane Database of Systematic Reviews

Tratamiento médico y quirúrgico de la miastenia ocular

Información

DOI:
https://doi.org/10.1002/14651858.CD005081.pub3Copiar DOI
Base de datos:
  1. Cochrane Database of Systematic Reviews
Versión publicada:
  1. 12 diciembre 2012see what's new
Tipo:
  1. Intervention
Etapa:
  1. Review
Grupo Editorial Cochrane:
  1. Grupo Cochrane de Neuromuscular

Copyright:
  1. Copyright © 2017 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.

Cifras del artículo

Altmetric:

Citado por:

Citado 0 veces por enlace Crossref Cited-by

Contraer

Autores

  • Michael Benatar

    Correspondencia a: Department of Neurology, University of Miami, Miami, USA

    [email protected]

  • Henry Kaminski

    Department of Neurology, George Washington University, Washington, USA

Contributions of authors

Michael Benatar and Henry Kaminski both evaluated each paper and extracted the relevant data. Michael Benatar wrote the first draft of the review. Henry Kaminski commented on and edited the draft to produce a final review. In 2010 both authors assessed 'Risk of bias' in the included studies. Both authors reviewed searches for updates and approved the text.

Declarations of interest

Dr Michael Benatar is the principal investigator on a RCT designed to compare the efficacy of prednisone plus pyridostigmine versus placebo plus pyridostigmine for the treatment of ocular myasthenia. He receives research funding from both the US National Institutes of Health (NIH) and the Food and Drug Administration for clinical trials in the field of MG.

Henry Kaminski is co‐investigator of the NIH‐sponsored trial of thymectomy for treatment of non‐thymomatous MG. He serves as consultant for Varleigh Limited, which is developing a drug for treatment of MG. He has served as a consultant for GlaxoSmithKline and serves on the Data and Safety Monitoring Board for a clinical trial sponsored by Cytokinetics. He receives royalties from Springer Publishing. He has performed legal consultations in cases related to MG.

Acknowledgements

The authors are grateful to Kate Jewitt and Richard Hughes at the Cochrane Neuromuscular Disease Group for their advice during the preparation of this review. We are also grateful to the late John Newsom‐Davis, Tony Swan, Philippe Gajdos and Sumit Singh for their helpful comments on an earlier draft of this review.

The editorial base of the Cochrane Neuromuscular Disease Group is supported by the MRC Centre for Neuromuscular Diseases and the Muscular Dystrophy Campaign.

Version history

Published

Title

Stage

Authors

Version

2012 Dec 12

Medical and surgical treatment for ocular myasthenia

Review

Michael Benatar, Henry Kaminski

https://doi.org/10.1002/14651858.CD005081.pub3

2006 Apr 19

Medical and surgical treatment for ocular myasthenia

Review

Michael Benatar, Henry Kaminski

https://doi.org/10.1002/14651858.CD005081.pub2

2005 Jan 24

Medical and surgical treatment for ocular myasthenia

Protocol

Michael Benatar, Henry Kaminski

https://doi.org/10.1002/14651858.CD005081

Differences between protocol and review

For the 2010 update we revised the 'Risk of bias' methodology and stated outcomes that would be included in a 'Summary of findings' table. At the 2012 update, the RevMan categories for review authors 'Risk of bias' judgements changed (Higgins 2011).

The protocol gives details of methodology that the review authors would have followed had more data been available (Benatar 2006).

Notes

A published, completed study (Benatar 2016) has been added to Characteristics of studies awaiting classification, pending a planned full update of the review.

PICO

Population
Intervention
Comparison
Outcome

El uso y la enseñanza del modelo PICO están muy extendidos en el ámbito de la atención sanitaria basada en la evidencia para formular preguntas y estrategias de búsqueda y para caracterizar estudios o metanálisis clínicos. PICO son las siglas en inglés de cuatro posibles componentes de una pregunta de investigación: paciente, población o problema; intervención; comparación; desenlace (outcome).

Para saber más sobre el uso del modelo PICO, puede consultar el Manual Cochrane.