Terapia ocupacional para adultos con problemas en las actividades de la vida diaria después de un accidente cerebrovascular
Appendices
Appendix 1. CENTRAL search strategy
#1 MeSH descriptor: [Cerebrovascular Disorders] explode all trees
#2 MeSH descriptor: [Basal Ganglia Cerebrovascular Disease] explode all trees
#3 MeSH descriptor: [Brain Ischemia] explode all trees
#4 MeSH descriptor: [Carotid Artery Diseases] explode all trees
#5 MeSH descriptor: [Cerebral Small Vessel Diseases] explode all trees
#6 MeSH descriptor: [Intracranial Arterial Diseases] explode all trees
#7 MeSH descriptor: [Intracranial Embolism and Thrombosis] explode all trees
#8 MeSH descriptor: [Intracranial Hemorrhages] explode all trees
#9 MeSH descriptor: [Stroke] explode all trees
#10 MeSH descriptor: [Stroke, Lacunar] explode all trees
#11 MeSH descriptor: [Vasospasm, Intracranial] explode all trees
#12 MeSH descriptor: [Vertebral Artery Dissection] explode all trees
#13 stroke* or poststroke or apoplexy* or cerebral vasc* or brain vasc* or cerebrovasc* or cva* or SAH
#14 (brain or cerebr* or cerebell* or vertebrobasil* or hemisphere* or intracran* or intracerebral or infratentorial or supratentorial or middle cerebral artery or MCA* or anterior circulation or posterior circulation or basilar artery or vertebral artery or space‐occupying) near/5 (ischemi* or ischaemi* or infarct* or thrombo* or emboli* or occlus* or hypoxi*)
#15 (brain* or cerebr* or cerebell* or intracerebral or intracran* or parenchymal or intraparenchymal or intraventricular or infratentorial or supratentorial or basal gangli* or putaminal or putamen or posterior fossa or hemispher* or subarachnoid) near/5 (hemorrhag* or haemorrhag* or hematoma* or haematoma* or bleed*)
#16 MeSH descriptor: [Hemiplegia] explode all trees
#17 MeSH descriptor: [Paresis] explode all trees
#18 Gait Disorders, Neurologic
#19 hemipleg* or hemipar* or paresis or paraparesis or paretic
#20 #1 or #2 or #3 or #4 or #5 or #6 or #7 or #8 or #9 or #10 or #11 or #12 or #13 or #14 or #15 or #16 or #17 or #18 or #19
#21 MeSH descriptor: [Rehabilitation] explode all trees
#22 MeSH descriptor: [Activities of Daily Living] explode all trees
#23 MeSH descriptor: [Recreation Therapy] explode all trees
#24 MeSH descriptor: [Occupational Therapy] explode all trees
#25 MeSH descriptor: [Rehabilitation, Vocational] explode all trees
#26MeSH descriptor: [Leisure Activities] explode all trees
#27 MeSH descriptor: [Recreation] explode all trees
#28 MeSH descriptor: [Automobile Driving] explode all trees
#29 MeSH descriptor: [Transportation] explode all trees
#30 MeSH descriptor: [Task Performance and Analysis] explode all trees
#31 MeSH descriptor: [Self Care] explode all trees
#32 MeSH descriptor: [Recovery of Function] explode all trees
#33 MeSH descriptor: [Goals] explode all trees
#34 MeSH descriptor: [Work] explode all trees
#35 MeSH descriptor: [Human Activities] explode all trees
#36 MeSH descriptor: [Social Adjustment] explode all trees
#37 MeSH descriptor: [Social Behavior] explode all trees
#38 MeSH descriptor: [Social Facilitation] explode all trees
#39 MeSH descriptor: [Social Environment] explode all trees
#40 MeSH descriptor: [Social Support] explode all trees
#41 occupation* near/5 (therap* or rehabil*)
#42 (activit* near/3 daily living) or ADL
#43 (self or personal) near/5 (care or manage*)
#44 recover* near/5 function*
#45 everyday near/3 (activit* or functioning)
#46 dressing or feeding or eating or toilet* or bathing or mobil* or driving or public transport*
#47 (daily or domestic or house or home) near/5 (activit* or task* or skill* or chore*)
#48 social near/5 (activit* or function* or support* or skill* or adjust* or behavio* or facilitat*)
#49 #21 or #22 or #23 or #24 or #25 or #26 or #27 or #28 or #29 or #30 or #31 or #32 or #33 or #34 or #35 or #36 or #37 or #38 or #39 or #40 or #41 or #42 or #43 or #44 or #45 or #46 or #47 or #48
#50 #20 and #49
Appendix 2. MEDLINE Ovid search strategy
1. cerebrovascular disorders/ or basal ganglia cerebrovascular disease/ or exp brain ischemia/ or exp carotid artery diseases/ or exp cerebral small vessel diseases/ or exp intracranial arterial diseases/ or exp "intracranial embolism and thrombosis"/ or exp intracranial hemorrhages/ or stroke/ or exp brain infarction/ or stroke, lacunar/ or vasospasm, intracranial/ or vertebral artery dissection/
2. (stroke$ or poststroke or apoplex$ or cerebral vasc$ or brain vasc$ or cerebrovasc$ or cva$ or SAH).tw.
3. ((brain or cerebr$ or cerebell$ or vertebrobasil$ or hemispher$ or intracran$ or intracerebral or infratentorial or supratentorial or middle cerebral artery or MCA$ or anterior circulation or posterior circulation or basilar artery or vertebral artery or space‐occupying) adj5 (isch?emi$ or infarct$ or thrombo$ or emboli$ or occlus$ or hypoxi$)).tw.
4. ((brain$ or cerebr$ or cerebell$ or intracerebral or intracran$ or parenchymal or intraparenchymal or intraventricular or infratentorial or supratentorial or basal gangli$ or putaminal or putamen or posterior fossa or hemispher$ or subarachnoid) adj5 (h?emorrhag$ or h?ematoma$ or bleed$)).tw.
5. hemiplegia/ or exp paresis/ or exp Gait Disorders, Neurologic/
6. (hemipleg$ or hemipar$ or paresis or paraparesis or paretic).tw.
7. or/1‐6
8. rehabilitation/ or "activities of daily living"/ or occupational therapy/ or recreation therapy/ or rehabilitation, vocational/
9. leisure activities/ or exp recreation/
10. automobile driving/ or exp transportation/
11. "Task Performance and Analysis"/ or self‐care/ or recovery of function/ or goals/
12. exp Work/ or Human Activities/
13. Social adjustment/ or Social behavior/ or Social facilitation/
14. Social environment/ or Social support/
15. (occupation$ adj5 (therap$ or rehabil$)).tw.
16. ((activit$ adj3 daily living) or ADL).tw.
17. ((self or personal) adj5 (care or manage$)).tw.
18. (recover$ adj5 function$).tw.
19. (everyday adj3 (activit$ or functioning)).tw.
20. (dressing or feeding or eating or toilet$ or bathing or mobil$ or driving or public transport$).tw.
21. ((daily or domestic or house or home) adj5 (activit$ or task$ or skill$ or chore$)).tw.
22. (social adj5 (activit$ or function$ or support$ or skill$ or adjust$ or behavio?r or facilitat$)).tw.
23. or/8‐22
24. Randomized Controlled Trials as Topic/
25. Random Allocation/
26. Controlled Clinical Trials as Topic/
27. control groups/
28. clinical trials as topic/ or clinical trials, phase i as topic/ or clinical trials, phase ii as topic/ or clinical trials, phase iii as topic/ or clinical trials, phase iv as topic/
29. double‐blind method/
30. single‐blind method/
31. Placebos/
32. placebo effect/
33. cross‐over studies/
34. randomized controlled trial.pt.
35. controlled clinical trial.pt.
36. (clinical trial or clinical trial phase i or clinical trial phase ii or clinical trial phase iii or clinical trial phase iv).pt.
37. (random$ or RCT or RCTs).tw.
38. (controlled adj5 (trial$ or stud$)).tw.
39. (clinical$ adj5 trial$).tw.
40. ((control or treatment or experiment$ or intervention) adj5 (group$ or subject$ or patient$)).tw.
41. (quasi‐random$ or quasi random$ or pseudo‐random$ or pseudo random$).tw.
42. ((control or experiment$ or conservative) adj5 (treatment or therapy or procedure or manage$)).tw.
43. ((singl$ or doubl$ or tripl$ or trebl$) adj5 (blind$ or mask$)).tw.
44. (cross‐over or cross over or crossover).tw.
45. (placebo$ or sham).tw.
46. trial.ti.
47. (assign$ or allocat$).tw.
48. controls.tw.
49. or/24‐48
50. 7 and 23 and 49
Appendix 3. Embase Ovid search strategy
1. cerebrovascular disease/ or brain disease/ or exp basal ganglion hemorrhage/ or exp brain hemangioma/ or exp brain hematoma/ or exp brain hemorrhage/ or exp brain infarction/ or exp brain ischemia/ or exp carotid artery disease/ or exp cerebral artery disease/ or exp cerebrovascular accident/ or exp cerebrovascular malformation/ or exp intracranial aneurysm/ or exp occlusive cerebrovascular disease/ or exp vertebrobasilar insufficiency/
2. (stroke$ or poststroke or apoplex$ or cerebral vasc$ or brain vasc$ or cerebrovasc$ or cva$ or SAH).tw.
3. ((brain or cerebr$ or cerebell$ or vertebrobasil$ or hemispher$ or intracran$ or intracerebral or infratentorial or supratentorial or middle cerebral artery or MCA$ or anterior circulation or posterior circulation or basilar artery or vertebral artery or space‐occupying) adj5 (isch?emi$ or infarct$ or thrombo$ or emboli$ or occlus$ or hypoxi$)).tw.
4. ((brain$ or cerebr$ or cerebell$ or intracerebral or intracran$ or parenchymal or intraparenchymal or intraventricular or infratentorial or supratentorial or basal gangli$ or putaminal or putamen or posterior fossa or hemispher$ or subarachnoid) adj5 (h?emorrhag$ or h?ematoma$ or bleed$)).tw.
5. exp hemiplegia/ or exp paresis/
6. exp hemiplegia/ or exp paresis/ or neurologic gait disorder/
7. (hemipleg$ or hemipar$ or paresis or paraparesis or paretic).tw.
8. or/1‐7
9. rehabilitation/ or occupational therapy/ or vocational rehabilitation/ or recreation therapy/
10. occupational therapist/
11. human activities/ or daily life activity/ or driving ability/ or exp recreation/ or exp personal hygiene/
12. exp self care/ or feeding/ or independence/ or home care/ or convalescence/
13. exp "traffic and transport"/
14. task performance/ or job performance/ or work/ or work capacity/ or work resumption/ or employment/
15. social behavior/ or social interaction/ or social adaptation/ or social learning/
16. social environment/ or social care/ or social life/ or social support/ or sociotherapy/ or psychosocial care/ or sociology/
17. (occupation$ adj5 (therap$ or rehabil$)).tw.
18. ((activit$ adj3 daily living) or ADL).tw.
19. ((self or personal) adj5 (care or manage$)).tw.
20. (recover$ adj3 function$).tw.
21. (everyday adj3 (activit$ or functioning)).tw.
22. (dressing or feeding or eating or toilet$ or bathing or mobil$ or driving or public transport$).tw.
23. ((daily or domestic or house or home) adj5 (activit$ or task$ or skill$ or chore$)).tw.
24. (social adj5 (activit$ or function$ or support$ or skill$ or adjust$ or behavio?r or facilitat$)).tw.
25. or/9‐24
26. Randomized Controlled Trial/ or "randomized controlled trial (topic)"/
27. Randomization/
28. Controlled clinical trial/ or "controlled clinical trial (topic)"/
29. control group/ or controlled study/
30. clinical trial/ or "clinical trial (topic)"/ or phase 1 clinical trial/ or phase 2 clinical trial/ or phase 3 clinical trial/ or phase 4 clinical trial/
31. Crossover Procedure/
32. Double Blind Procedure/
33. Single Blind Procedure/ or triple blind procedure/
34. placebo/ or placebo effect/
35. (random$ or RCT or RCTs).tw.
36. (controlled adj5 (trial$ or stud$)).tw.
37. (clinical$ adj5 trial$).tw.
38. ((control or treatment or experiment$ or intervention) adj5 (group$ or subject$ or patient$)).tw.
39. (quasi‐random$ or quasi random$ or pseudo‐random$ or pseudo random$).tw.
40. ((control or experiment$ or conservative) adj5 (treatment or therapy or procedure or manage$)).tw.
41. ((singl$ or doubl$ or tripl$ or trebl$) adj5 (blind$ or mask$)).tw.
42. (cross‐over or cross over or crossover).tw.
43. (placebo$ or sham).tw.
44. trial.ti.
45. (assign$ or allocat$).tw.
46. controls.tw.
47. or/26‐46
48. 8 and 25 and 47
Appendix 4. CINAHL EBSCO search strategy
S1 (MH "Cerebrovascular Disorders") OR (MH "Basal Ganglia Cerebrovascular Disease+") OR (MH "Carotid Artery Diseases+") OR (MH "Cerebral Ischemia+") OR (MH "Cerebral Vasospasm") OR (MH "Intracranial Arterial Diseases+") OR (MH "Intracranial Embolism and Thrombosis") OR (MH "Intracranial Hemorrhage+") OR (MH "Stroke") OR (MH "Vertebral Artery Dissections") OR (MH "Stroke Patients") OR (MH "Stroke Units")
S2 TI ( stroke or poststroke or post‐stroke or cerebrovasc* or brain vasc* or cerebral vasc or cva or apoplex or SAH ) or AB ( stroke or poststroke or post‐stroke or cerebrovasc* or brain vasc* or cerebral vasc or cva or apoplex or SAH)
S3TI ( brain* or cerebr* or cerebell* or intracran* or intracerebral ) or AB ( brain* or cerebr* or cerebell* or intracran* or intracerebral)
S4TI ( ischemi* or ischaemi* or infarct* or thrombo* or emboli* or occlus* ) or AB ( ischemi* or ischaemi* or infarct* or thrombo* or emboli* or occlus*)
S5S3 AND S4
S6TI ( brain* or cerebr* or cerebell* or intracerebral or intracranial or subarachnoid ) or AB ( brain* or cerebr* or cerebell* or intracerebral or intracranial or subarachnoid)
S7TI ( haemorrhage* or hemorrhage* or haematoma* or hematoma* or bleed* ) or AB ( haemorrhage* or hemorrhage* or haematoma* or hematoma* or bleed*)
S8S6 AND S7
S9S1 OR S2 OR S5 OR S8
S10(MH "Leisure Activities") OR (MH "Recreation+") OR (MH "Rehabilitation") OR (MH "Activities of Daily Living+") OR (MH "Occupational Therapy") OR (MH "Home Occupational Therapy")
S11(MH "Automobile Driving")
S12(MH "Task Performance and Analysis") OR (MH "Self Care") OR (MH "Work")
S13(MH "Social Adjustment") OR (MH "Social Behavior") OR (MH "Social Environment")
S14TI ( ((activit* N3 daily living) or ADL) ) OR AB ( ((activit* N3 daily living) or ADL) )
S15TI ( (occupation* N5 (therap$ or rehabil*)) ) OR AB ( (occupation* N5 (therap$ or rehabil*)) )
S16TI ( ((self or personal) N5 (care or manage*)) ) OR AB ( ((self or personal) N5 (care or manage*)) )
S17TI (recover* N5 function*) OR AB (recover* N5 function*)
S18TI ( (everyday N3 (activit* or functioning)) ) OR AB ( (everyday N3 (activit* or functioning)) )
S19TI ( (dressing or feeding or eating or toilet* or bathing or mobil* or driving or public transport*) ) OR AB ( (dressing or feeding or eating or toilet* or bathing or mobil* or driving or public transpo )
S20TI ( ((daily or domestic or house or home) N5 (activit* or task* or skill* or chore*)) ) OR AB ( ((daily or domestic or house or home) N5 (activit* or task* or skill* or chore*)) )
S21TI ( (social N5 (activit* or function* or support* or skill* or adjust* or behavio?r or facilitat*)) ) OR AB ( (social N5 (activit* or function* or support* or skill* or adjust* or behavio?r or facilitat*)) )
S22S10 OR S11 OR S12 OR S13 OR S14 OR S15 OR S16 OR S17 OR S18 OR S19 OR S20 OR S21
S23(MH "Randomized Controlled Trials") or (MH "Random Assignment") or (MH "Random Sample+")
S24(MH "Clinical Trials") or (MH "Intervention Trials") or (MH "Therapeutic Trials")
S25(MH "Double‐Blind Studies") or (MH "Single‐Blind Studies") or (MH "Triple‐Blind Studies")
S26(MH "Control (Research)") or (MH "Control Group") or (MH "Placebos") or (MH "Placebo Effect")
S27(MH "Crossover Design") OR (MH "Quasi‐Experimental Studies")
S28PT (clinical trial or randomized controlled trial)
S29TI (random* or RCT or RCTs) or AB (random* or RCT or RCTs)
S30TI (controlled N5 (trial* or stud*)) or AB (controlled N5 (trial* or stud*))
S31TI (clinical* N5 trial*) or AB (clinical* N5 trial*)
S32TI ((control or treatment or experiment* or intervention) N5 (group* or subject* or patient*)) or AB ((control or treatment or experiment* or intervention) N5 (group* or subject* or patient*))
S33((control or experiment* or conservative) N5 (treatment or therapy or procedure or manage*)) or AB ((control or experiment* or conservative) N5 (treatment or therapy or procedure or manage*))
S34TI ((singl* or doubl* or tripl* or trebl*) N5 (blind* or mask*)) or AB ((singl* or doubl* or tripl* or trebl*) N5 (blind* or mask*))
S35TI (cross‐over or cross over or crossover) or AB (cross‐over or cross over or crossover)
S36TI (placebo* or sham) or AB (placebo* or sham)
S37TI trial
S38TI (assign* or allocat*) or AB (assign* or allocat*)
S39TI controls or AB controls
S40TI (quasi‐random* or quasi random* or pseudo‐random* or pseudo random*) or AB (quasi‐random* or quasi random* or pseudo‐random* or pseudo random*)
S41S23 OR S24 OR S25 OR S26 OR S27 OR S28 OR S29 OR S30 OR S31 OR S32 OR S33 OR S34 OR S35 OR S36 OR S37 OR S38 OR S39 OR S40
S42S9 AND S22 AND S41
Appendix 5. PsycINFO Ovid search strategy
1. cerebrovascular disorders/ or cerebral hemorrhage/ or exp cerebral ischemia/ or cerebral small vessel disease/ or cerebrovascular accidents/ or subarachnoid hemorrhage/
2. (stroke$ or poststroke or apoplex$ or cerebral vasc$ or brain vasc$ or cerebrovasc$ or cva$ or SAH).tw.
3. ((brain or cerebr$ or cerebell$ or vertebrobasil$ or hemispher$ or intracran$ or intracerebral or infratentorial or supratentorial or middle cerebral artery or MCA$ or anterior circulation or posterior circulation or basilar artery or vertebral artery or space‐occupying) adj5 (isch?emi$ or infarct$ or thrombo$ or emboli$ or occlus$ or hypoxi$)).tw.
4. ((brain$ or cerebr$ or cerebell$ or intracerebral or intracran$ or parenchymal or intraparenchymal or intraventricular or infratentorial or supratentorial or basal gangli$ or putaminal or putamen or posterior fossa or hemispher$ or subarachnoid) adj5 (h?emorrhag$ or h?ematoma$ or bleed$)).tw.
5. hemiparesis/ or hemiplegia/
6. (hemipleg$ or hemipar$ or paresis or paraparesis or paretic).tw.
7. 1 or 2 or 3 or 4 or 5 or 6
8. rehabilitation/ or occupational therapy/ or "activities of daily living"/
9. exp vocational rehabilitation/ or work adjustment training/ or occupational adjustment/ or supported employment/
10. recreation therapy/ or leisure time/ or daily activities/
11. automobiles/ or transportation/
12. self‐care skills/
13. social adjustment/ or social behavior/ or social adjustment/ or social facilitation/
14. social environments/ or social support/
15. (occupation$ adj5 (therap$ or rehabil$)).tw.
16. ((activit$ adj3 daily living) or ADL).tw.
17. ((self or personal) adj5 (care or manage$)).tw.
18. (recover$ adj5 function$).tw.
19. (everyday adj3 (activit$ or functioning)).tw.
20. (dressing or feeding or eating or toilet$ or bathing or mobil$ or driving or public transport$).tw.
21. ((daily or domestic or house or home) adj5 (activit$ or task$ or skill$ or chore$)).tw.
22. (social adj5 (activit$ or function$ or support$ or skill$ or adjust$ or behavio?r or facilitat$)).tw.
23. or/8‐22
24. clinical trials/ or treatment effectiveness evaluation/ or placebo/
25. (random$ or RCT or RCTs).tw.
26. (controlled adj5 (trial$ or stud$)).tw.
27. (clinical$ adj5 trial$).tw.
28. ((control or treatment or experiment$ or intervention) adj5 (group$ or subject$ or patient$)).tw.
29. (quasi‐random$ or quasi random$ or pseudo‐random$ or pseudo random$).tw.
30. ((control or experiment$ or conservative) adj5 (treatment or therapy or procedure or manage$)).tw.
31. ((singl$ or doubl$ or tripl$ or trebl$) adj5 (blind$ or mask$)).tw.
32. (cross‐over or cross over or crossover).tw.
33. (placebo$ or sham).tw.
34. trial.ti.
35. (assign$ or allocat$).tw.
36. controls.tw.
37. or/24‐36
38. 7 and 23 and 37
Appendix 6. AMED Ovid search strategy
1. cerebrovascular disorders/ or cerebral hemorrhage/ or cerebral infarction/ or cerebral ischemia/ or cerebrovascular accident/ or stroke/
2. (stroke or poststroke or post‐stroke or cerebrovasc$ or brain vasc$ or cerebral vasc$ or cva$ or apoplex$ or SAH).tw.
3. ((brain or cerebr$ or cerebell$ or vertebrobasil$ or hemispher$ or intracran$ or intracerebral or infratentorial or supratentorial or middle cerebral artery or MCA$ or anterior circulation or posterior circulation or basilar artery or vertebral artery or space‐occupying) adj5 (isch?emi$ or infarct$ or thrombo$ or emboli$ or occlus$ or hypoxi$)).tw.
4. ((brain$ or cerebr$ or cerebell$ or intracerebral or intracran$ or parenchymal or intraparenchymal or intraventricular or infratentorial or supratentorial or basal gangli$ or putaminal or putamen or posterior fossa or hemispher$ or subarachnoid) adj5 (h?emorrhag$ or h? ematoma$ or bleed$)).tw.
5. hemiplegia/ or exp gait disorders/
6. (hemipleg$ or hemipar$ or paresis or paretic).tw.
7. 1 or 2 or 3 or 4 or 5 or 6
8. rehabilitation/ or exp rehabilitation vocational/ or recreation/
9. human activities/ or "activities of daily living"/ or exp bathing/ or exp leisure activities/ or exp automobile driving/ or exp employment/
10. "task performance and analysis"/
11. self care/ or "recovery of function"/ or goals/
12. Social behavior/ or Social support/ or Social environment/
13. (occupation$ adj5 (therap$ or rehabil$)).tw.
14. ((activit$ adj3 daily living) or ADL).tw.
15. ((self or personal) adj5 (care or manage$)).tw.
16. (recover$ adj5 function$).tw.
17. (everyday adj3 (activit$ or functioning)).tw.
18. (dressing or feeding or eating or toilet$ or bathing or mobil$ or driving or public transport$).tw.
19. ((daily or domestic or house or home) adj5 (activit$ or task$ or skill$ or chore$)).tw.
20. (social adj5 (activit$ or function$ or support$ or skill$ or adjust$ or behavio?r or facilitat$)).tw.
21. or/8‐20
22. clinical trials/ or randomized controlled trials/ or random allocation/
23. double blind method/ or single blind method/
24. placebos/
25. (random$ or RCT or RCTs).tw.
26. (controlled adj5 (trial$ or stud$)).tw.
27. (clinical$ adj5 trial$).tw.
28. ((control or treatment or experiment$ or intervention) adj5 (group$ or subject$ or patient$)).tw.
29. (quasi‐random$ or quasi random$ or pseudo‐random$ or pseudo random$).tw.
30. ((control or experiment$ or conservative) adj5 (treatment or therapy or procedure or manage$)).tw.
31. ((singl$ or doubl$ or tripl$ or trebl$) adj5 (blind$ or mask$)).tw.
32. (cross‐over or cross over or crossover).tw.
33. (placebo$ or sham).tw.
34. trial.ti.
35. (assign$ or allocat$).tw.
36. controls.tw.
37. or/22‐36
38. 7 and 21 and 37
Appendix 7. Web of Science search strategy
#1TS=(stroke or poststroke or post‐stroke or cerebrovasc* or brain vasc* or cerebral vasc* or cva* or apoplex* or SAH)
#2TS=((brain* or cerebr* or cerebell* or intracran* or intracerebral) NEAR/5 (isch$emi* or nfarct* or thrombo* or emboli* or occlus*))
#3TS=((brain* or cerebr* or cerebell* or intracerebral or intracranial or subarachnoid) NEAR/5 (haemorrhage* or hemorrhage* or haematoma* or hematoma* or bleed*))
#4TS=(hemipleg* or hemipar* or paresis or paretic or hemineglect or hemi‐neglect)
#5TS=((unilateral or spatial or hemi$spatial or visual) NEAR/5 neglect)
#6#5 OR #4 OR #3 OR #2 OR #1
#7TS=(occupation* NEAR/5 (therap$ or rehabil*))
#8TS=((activit* NEAR/3 daily living) or ADL)
#9TS=((self or personal) NEAR/5 (care or manage*))
#10TS=(recover* NEAR/5 function*)
#11TS=(everyday NEAR/3 (activit* or functioning))
#12TS=(dressing or feeding or eating or toilet* or bathing or mobil* or driving or public transport*)
#13TS=((daily or domestic or house or home) NEAR/5 (activit* or task* or skill* or chore*))
#14TS=(social NEAR/5 (activit* or function* or support* or skill* or adjust* or behavio$r or facilitat*))
#15#14 OR #13 OR #12 OR #11 OR #10 OR #9 OR #8 OR #7
#16TS=(random* or RCT or RCTs)
#17TS=(controlled NEAR/5 (trial* or stud*))
#18TS=(clinical* NEAR/5 trial*)
#19TS=((control or treatment or experiment* or intervention) NEAR/5 (group* or subject* or patient*))
#20TS=(quasi‐random* or quasi random* or pseudo‐random* or pseudo random*)
#21TS=((control or experiment* or conservative) NEAR/5 (treatment or therapy or procedure or manage*))
#22TS=((singl* or doubl* or tripl* or trebl*) NEAR/5 (blind* or mask*))
#23TS=(cross‐over or cross over or crossover)
#24TS=(placebo* or sham)
#25TI=trial
#26TS=(assign* or allocat*)
#27TS=controls
#28#27 OR #26 OR #25 OR #24 OR #23 OR #22 OR #21 OR #20 OR #19 OR #18 OR #17 OR #16
#29#28 AND #15 AND #6
Appendix 8. OpenGrey search strategy
stroke AND (occupational therapy OR rehabilitation)
Appendix 9. US National Institutes of Health Ongoing Trials Register (ClinicalTrials.gov) and World Health Organization International Clinical Trials Registry Platform search strategies
stroke AND (occupational therapy OR rehabilitation)
Flow diagram of search conducted in January 2017.
Risk of bias graph: review authors' judgements about each risk of bias item presented as percentages across all included studies.
Risk of bias summary: review authors' judgements about each risk of bias item for each included study.
Comparison 1: Occupational therapy versus no routine input, Outcome 1: Activities of daily living
Comparison 1: Occupational therapy versus no routine input, Outcome 2: Death or 'poor outcome' (deterioration or dependency)
Comparison 1: Occupational therapy versus no routine input, Outcome 3: Death by the end of scheduled follow‐up
Comparison 1: Occupational therapy versus no routine input, Outcome 4: Death or requiring institutional care by the end of scheduled follow up
Comparison 1: Occupational therapy versus no routine input, Outcome 5: Death or dependency by the end of scheduled follow‐up
Comparison 1: Occupational therapy versus no routine input, Outcome 6: Extended activities of daily living scores
Comparison 1: Occupational therapy versus no routine input, Outcome 7: Mood or distress scores
Comparison 1: Occupational therapy versus no routine input, Outcome 8: Sensitivity to missing data (odds of poor outcome: better)
Comparison 1: Occupational therapy versus no routine input, Outcome 9: Sensitivity to missing data (odds of poor outcome: worse)
| Occupational therapy compared to usual or no care for stroke | ||||||
| Patient or population: adults with stroke Intervention: occupational therapy | ||||||
| Outcomes | Illustrative comparative risks* (95% CI) | Relative effect | No of participants | Quality of the evidence | Comments | |
|---|---|---|---|---|---|---|
| Assumed risk | Corresponding risk | |||||
| Usual or no care | Occupational therapy | |||||
| Activities of daily living at end of scheduled follow‐up. | The mean activities of daily living score was 80.43 | The mean activities of daily living score in the intervention groups was | 749 | ⊕⊕⊝⊝ | A standard deviation of 0.17 represents a small difference between groups | |
| Odds of death or a poor outcome at end of scheduled follow‐up. | Study population | Peto OR 0.71 | 771 | ⊕⊕⊝⊝ | ||
| 440 per 1000 | 313 per 1000 | |||||
| Moderate | ||||||
| Extended Activities of Daily Livingat end of scheduled follow‐up. | The mean Extended Activities of Daily Living score was 33.33 | The mean Extended Activities of Daily Living score in the intervention groups was | 665 | ⊕⊕⊝⊝ | A standard deviation of 0.22 represents a small difference between groups | |
| Mood or distress scores | The mean depression score was 19.83 | The mean mood or distress scores in the intervention groups was | 519 | ⊕⊕⊝⊝ | A standard deviation of 0.08 represents a small difference between groups | |
| *The basis for the assumed risk (e.g. the median control group risk across studies) is provided in footnotes. The corresponding risk (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI). | ||||||
| GRADE Working Group grades of evidence | ||||||
| 1 We downgraded the quality of this evidence one level for serious risk of selection, performance and detection biases (the latter only for subjective outcomes) 2 We further downgraded by one level for serious imprecision (due to small sample sizes, few events and wide confidence intervals). 3 Data taken from a study (Parker 2001) in the meta‐analysis that is representative of the population and intervention and at low risk of bias. | ||||||
| Study | N (I) | n (I) | Dead (I) | Missing (I) | N (C) | n (C) | Dead (C) | Missing (C) |
|---|---|---|---|---|---|---|---|---|
| 30 | 30 | 0 | 0 | 23 | 23 | 0 | 0 | |
| 55 | 46 | 9 | 0 | 55 | 39 | 11 | 5 | |
| 67 | 60 | 6 | 1 | 71 | 62 | 5 | 4 | |
| 53 | 45 | 5 | 3 | 58 | 38 | 7 | 13 | |
| 156 | 106 | 15 | 35 | 157 | 110 | 11 | 36 | |
| 5 | 5 | 0 | 0 | 5 | 0 | 0 | 0 | |
| 15 | 12 | 0 | 3 | 15 | 15 | 0 | 0 | |
| 94 | 84 | 6 | 4 | 91 | 79 | 7 | 5 | |
| C: control group (usual care or no intervention) | ||||||||
| Study | N (I) | n (I) | Dead (I) or deteriorate | Missing (I) | N (C) | n (C) | Dead (C) or deteriorate | Missing (C) |
|---|---|---|---|---|---|---|---|---|
| 55 | 55 | 9 + 24 = 33 | 0 | 55 | 54 | 11 + 21 = 32 | 1 | |
| 53 | 53 | 5 + 1 = 6 | 0 | 58 | 58 | 7 + 7 = 14 | 0 | |
| 67 | 66 | 6 + 27 = 33 | 1 | 71 | 67 | 5 + 36 = 41 | 4 | |
| 156 | 121 | 15 + 36 = 51 | 35 | 157 | 121 | 11 + 45 = 56 | 36 | |
| 94 | 90 | 6 + 12 = 18 | 4 | 91 | 86 | 7 + 20 = 27 | 5 | |
| C: control group (usual care or no intervention) | ||||||||
| Study | N (I) | n (I) | Dead (I) | Missing (I) | N (C) | n (C) | Dead (C) | Missing (C) |
|---|---|---|---|---|---|---|---|---|
| 30 | 30 | 0 | 0 | 23 | 23 | 0 | 0 | |
| 55 | 55 | 9 | 0 | 55 | 55 | 11 | 0 | |
| 67 | 67 | 6 | 0 | 71 | 71 | 5 | 0 | |
| 53 | 53 | 5 | 0 | 58 | 58 | 7 | 0 | |
| 156 | 156 | 15 | 0 | 157 | 157 | 11 | 0 | |
| 5 | 5 | 0 | 0 | 5 | 5 | 0 | 0 | |
| 15 | 15 | 0 | 0 | 15 | 15 | 0 | 0 | |
| 94 | 94 | 6 | 0 | 91 | 91 | 7 | 0 | |
| C: control group (usual care or no intervention) | ||||||||
| Study | N (I) | n (I) | Dead (I) or institutionalised | Missing (I) | N (C) | n (C) | Dead (C) or institutionalised | Missing (C) |
|---|---|---|---|---|---|---|---|---|
| 55 | 55 | 9 + 16 = 25 | 0 | 55 | 54 | 11 + 18 = 29 | 1 | |
| 53 | 53 | 5 + 1 = 6 | 0 | 58 | 58 | 7 + 7 = 14 | 0 | |
| 67 | 67 | 6 + 4 = 10 | 0 | 71 | 71 | 5 + 4 = 9 | 0 | |
| 156 | 156 | 15 + 9 = 24 | 0 | 157 | 157 | 11+9 = 20 | 0 | |
| C: control group (usual care or no intervention) | ||||||||
| Study | N (I) | n (I) | Dead (I) or dependent | Missing (I) | N (C) | n (C) | Dead (C) or dependent | Missing (C) | Measure |
|---|---|---|---|---|---|---|---|---|---|
| 55 | 55 | 9 + 32 = 41 | 0 | 55 | 54 | 11 + 30 = 41 | 1 | Barthel < 15 | |
| 67 | 66 | 6 + 21 = 27 | 1 | 71 | 66 | 6 + 14 = 20 | 5 | Barthel < 15 | |
| 156 | 121 | 15+36 = 51 | 35 | 157 | 121 | 11 + 45 = 56 | 36 | Barthel < 15 | |
| 94 | 90 | 6 + 12 = 18 | 4 | 91 | 86 | 7 + 20 = 27 | 5 | Barthel < 15 | |
| C: control group (usual care or no intervention) | |||||||||
| Study | N (I) | n (I) | Dead (I) | Missing (I) | N (C) | n (C) | Dead (C) | Missing (C) |
|---|---|---|---|---|---|---|---|---|
| 55 | 45 | 9 | 1 | 55 | 39 | 11 | 5 | |
| 67 | 60 | 6 | 1 | 71 | 62 | 5 | 4 | |
| 53 | 45 | 5 | 3 | 58 | 38 | 7 | 13 | |
| 156 | 104 | 15 | 37 | 157 | 109 | 11 | 37 | |
| 5 | 5 | 0 | 0 | 5 | 5 | 0 | 0 | |
| 94 | 84 | 6 | 4 | 91 | 79 | 7 | 5 | |
| C: control group (usual care or no intervention) | ||||||||
| Study | N (I) | n (I) | Dead (I) | Missing (I) | N (C) | n (C) | Dead (C) | Missing (C) |
|---|---|---|---|---|---|---|---|---|
| 67 | 54 | 6 | 7 | 71 | 54 | 5 | 12 | |
| C: control group (usual care or no intervention) | ||||||||
| Study | N (I) | n (I) | Dead (I) | Missing (I) | N (C) | n (C) | Dead (C) | Missing (C) |
|---|---|---|---|---|---|---|---|---|
| 55 | 41 | 9 | 5 | 55 | 31 | 11 | 13 | |
| 53 | 39 | 5 | 9 | 58 | 34 | 7 | 17 | |
| 156 | 105 | 15 | 36 | 157 | 109 | 11 | 37 | |
| 94 | 83 | 6 | 5 | 91 | 77 | 7 | 7 | |
| C: control group (usual care or no intervention) | ||||||||
| Outcome or subgroup title | No. of studies | No. of participants | Statistical method | Effect size |
| 1.1 Activities of daily living Show forest plot | 7 | 749 | Std. Mean Difference (IV, Fixed, 95% CI) | 0.17 [0.03, 0.31] |
| 1.2 Death or 'poor outcome' (deterioration or dependency) Show forest plot | 5 | 771 | Peto Odds Ratio (Peto, Fixed, 95% CI) | 0.71 [0.52, 0.96] |
| 1.3 Death by the end of scheduled follow‐up Show forest plot | 8 | 950 | Peto Odds Ratio (Peto, Fixed, 95% CI) | 1.02 [0.65, 1.61] |
| 1.4 Death or requiring institutional care by the end of scheduled follow up Show forest plot | 4 | 671 | Peto Odds Ratio (Peto, Fixed, 95% CI) | 0.89 [0.60, 1.32] |
| 1.5 Death or dependency by the end of scheduled follow‐up Show forest plot | 4 | 659 | Peto Odds Ratio (Peto, Fixed, 95% CI) | 0.89 [0.64, 1.23] |
| 1.6 Extended activities of daily living scores Show forest plot | 5 | 665 | Std. Mean Difference (IV, Fixed, 95% CI) | 0.22 [0.07, 0.37] |
| 1.7 Mood or distress scores Show forest plot | 4 | 519 | Std. Mean Difference (IV, Fixed, 95% CI) | 0.08 [‐0.09, 0.26] |
| 1.8 Sensitivity to missing data (odds of poor outcome: better) Show forest plot | 5 | 857 | Peto Odds Ratio (Peto, Fixed, 95% CI) | 0.75 [0.56, 1.00] |
| 1.9 Sensitivity to missing data (odds of poor outcome: worse) Show forest plot | 5 | 857 | Peto Odds Ratio (Peto, Fixed, 95% CI) | 0.75 [0.56, 0.99] |
