Scolaris Content Display Scolaris Content Display

Cochrane Database of Systematic Reviews

Fecundación in vitro para la subfertilidad idiopática

Información

DOI:
https://doi.org/10.1002/14651858.CD003357.pub5Copiar DOI
Base de datos:
  1. Cochrane Database of Systematic Reviews
Versión publicada:
  1. 27 septiembre 2023see what's new
Tipo:
  1. Intervention
Etapa:
  1. Review
Grupo Editorial Cochrane:
  1. Grupo Cochrane de Ginecología y fertilidad

Copyright:
  1. Copyright © 2023 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.

Cifras del artículo

Altmetric:

Citado por:

Citado 0 veces por enlace Crossref Cited-by

Contraer

Autores

  • Sesh Kamal Sunkara

    Correspondencia a: Division of Women's Health, Faculty of Life Sciences & Medicine, King's College London, London, UK

    [email protected]

    Kings Fertility, London, UK

  • Mohan S Kamath

    Department of Reproductive Medicine and Surgery, Christian Medical College, Vellore, India

  • Zabeena Pandian

    Aberdeen Fertility Unit, NHS Grampian, Aberdeen, UK

  • Ahmed Gibreel

    Obstetrics & Gynaecology, Faculty of Medicine, Mansoura University, Mansoura, Egypt

  • Siladitya Bhattacharya

    School of Medicine Medical Sciences and Nutrition, University of Aberdeen, Aberdeen, UK

Contributions of authors

Sesh Kamal Sunkara: screening of studies, data extraction, trial selection, quality assessment, data entry, analysis and updating the review.

Mohan S Kamath: update of the review. He also independently selected trials for inclusion in the review, extracted data, and performed risk of bias assessment and quality assessment of the selected trials.

Zabeena Pandian: development of the protocol, literature search, data extraction, trial selection, quality assessment, data entry, analysis, writing of previous drafts of the review.

Ahmed Gibreel: trial selection, quality assessment, data extraction, and analysis for the updated review.

Siladitya Bhattacharya: initiation of the original review, trial selection, quality assessment, responsible for final draft of the updated review.

Sources of support

Internal sources

  • Department of Obstetrics & Gynaecology, University of Aberdeen, UK

    Research time for Prof Bhattacharya

External sources

  • None, Other

    None

Declarations of interest

SKS: member European Society of Human Reproduction and Embryology (ESHRE) guideline development group on Unexplained Infertility. Speaker at non‐promotional scientific meetings organised by Ferring, Merck, MSD.

MSK: is an editor of Cochrane Gynaecology and Fertility. He was not involved in the editorial process or decision‐making for this article.

ZP: none in relation to this work.

AG: none in relation to this work.

SB: invited speaker at scientific meetings organised by Ferring, Merck, Organon. Speaker fees paid to University of Aberdeen. Author of a book on infertility (Cambridge University Press) that generates royalties. Member ESHRE guideline development group on Unexplained Infertility.

Acknowledgements

We thank Marian Showell (Information Specialist) for running the searches for this review and the Cochrane Gynaecology and Fertility Group for support provided.

We thank Dr Lucy Prentice, Dr Hector Georgiou, and Melissa Vercoe as reviewers, and Lisa Winer of Cochrane Central Production Service for copy editing the draft.

We thank Anupa Nandi for providing additional information for the study Nandi 2017.

Version history

Published

Title

Stage

Authors

Version

2023 Sep 27

In vitro fertilisation for unexplained subfertility

Review

Sesh Kamal Sunkara, Mohan S Kamath, Zabeena Pandian, Ahmed Gibreel, Siladitya Bhattacharya

https://doi.org/10.1002/14651858.CD003357.pub5

2015 Nov 19

In vitro fertilisation for unexplained subfertility

Review

Zabeena Pandian, Ahmed Gibreel, Siladitya Bhattacharya

https://doi.org/10.1002/14651858.CD003357.pub4

2012 Apr 18

In vitro fertilisation for unexplained subfertility

Review

Zabeena Pandian, Ahmed Gibreel, Siladitya Bhattacharya

https://doi.org/10.1002/14651858.CD003357.pub3

2005 Apr 20

In vitro fertilisation for unexplained subfertility

Review

Zabeena Pandian, Ahmed Fathy Gibreel, Siladitya Bhattacharya

https://doi.org/10.1002/14651858.CD003357.pub2

2002 Apr 22

In vitro fertilisation for unexplained subfertility

Review

Zabeena Pandian, Siladitiya Bhattacharya, Dimitrios Nikolaou, Luke Vale, Allan Templeton

https://doi.org/10.1002/14651858.CD003357

Differences between protocol and review

We removed gamete intrafallopian transfer as an intervention in the review. We replaced the primary outcome of cumulative live birth rate per woman with live birth rate per woman, and the secondary outcome of cumulative pregnancy rate per woman with clinical pregnancy rate per woman, as the majority of in vitro fertilisation (IVF) studies reported live birth and clinical pregnancy following one embryo transfer as the primary outcome. For the comparison IVF versus intrauterine insemination (IUI) + ovarian stimulation with gonadotropins, we performed stratified analysis based on pretreatment status. We added the comparison IVF versus IUI + letrozole.

We edited the definition of live birth (Zegers‐Hochschild 2017).

PICO

Population
Intervention
Comparison
Outcome

El uso y la enseñanza del modelo PICO están muy extendidos en el ámbito de la atención sanitaria basada en la evidencia para formular preguntas y estrategias de búsqueda y para caracterizar estudios o metanálisis clínicos. PICO son las siglas en inglés de cuatro posibles componentes de una pregunta de investigación: paciente, población o problema; intervención; comparación; desenlace (outcome).

Para saber más sobre el uso del modelo PICO, puede consultar el Manual Cochrane.