This is a protocol for a Cochrane Review (Intervention). The objectives are as follows:

To assess the role of corticosteroids for a reduction in the incidence of coronary aneurysms in Kawasaki disease (KD), as either first‐line or second‐line treatment. Corticosteroids may be given alone or in conjunction with other accepted KD treatments. Secondary objectives will include to determine the effects of steroids on mortality, biochemical parameters and duration of acute symptoms including fever as well as evaluating their safety in KD and efficacy in relevant population subgroups.