This is a protocol for a Cochrane Review (Intervention). The objectives are as follows:

To assess the effectiveness of multidisciplinary rehabilitation in persons after primary brain tumour treatment, and specifically to explore the following areas:

• Does organised multidisciplinary rehabilitation achieve better outcomes than the absence of such services in persons after primary brain tumour treatment?

• Which type of programmes are effective and in which setting?

• Does a greater intensity (time and expertise, or both) of rehabilitation lead to greater gains?

• Which specific outcomes are influenced (survival, dependency, social integration, mood, quality of life)?