This is a protocol for a Cochrane Review (Intervention). The objectives are as follows:

Primary objective: to evaluate the effectiveness of educational interventions for managing cancer‐related fatigue in adults.

Secondary objective: to explore the effectiveness of educational interventions for managing cancer‐related fatigue in different types of adult cancer populations where data are available. This could include groupings by tumour type, type of cancer treatment, stage of treatment (either during or after treatment), and stage of disease (early versus metastatic cancer).