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Cochrane Database of Systematic Reviews Protocol - Intervention

Antiemetics for reducing vomiting related to acute gastroenteritis in children and adolescents

This is not the most recent version

Abstract

This is a protocol for a Cochrane Review (Intervention). The objectives are as follows:

The objective of this review is to provide reliable evidence regarding the clinical effectiveness and safety of antiemetics for vomiting due to gastroenteritis by comparing clinical outcomes expressed as cessation of vomiting and the eventual resumption of oral rehydration therapy. Additionally, we will look into the number of children and adolescents who had be admitted to hospital and the number of subjects who required intravenous fluids.
The following null hypothesis will be tested: for gastroenteritis induced vomiting there is no difference in the time taken to achieve cessation of vomiting between patients taking antiemetics as compared to those who have received placebo or nothing.