This is a protocol for a Cochrane Review (Intervention). The objectives are as follows:

To compare intravesical botulinum toxin injection with other treatments for neurogenic and idiopathic OAB in adults.

These hypotheses will be addressed.
1 Intravesical injection of botulinum toxin is better than placebo or no treatment.
2 Intravesical injection of botulinum toxin is better than pharmacological interventions.
3 Intravesical injection of botulinum toxin is better than other non‐pharmacological interventions.
4 Higher doses of intravesical botulinum toxin are better than lower doses.
5 Intravesical injection of botulinum toxin combined with other treatments is better than other treatments alone.
6 One formulation of botulinum toxin is better than another.