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Cochrane Database of Systematic Reviews Protocol - Intervention

Rapid versus slow withdrawal of antiepileptic drugs

This is not the most recent version

Abstract

This is a protocol for a Cochrane Review (Intervention). The objectives are as follows:

1. To quantify risk of seizure recurrence after rapid (taper period of three months or less) or slow (taper period or more than three months) discontinuation of antiepileptic drugs in adults with epilepsy who are in remission.
2.To quantify the risk of seizure recurrence after rapid (taper period of three months or less) or slow (taper period of more than three months) discontinuation of antiepileptic drugs in children with epilepsy who are in remission.
3. To attempt to assess which variables modify the risk of seizure recurrence.