This is a protocol for a Cochrane Review (Intervention). The objectives are as follows:

To systematically assess the effectiveness and safety of aerobic and/or muscular endurance exercises ‐ administered during adjuvant radiotherapy, chemotherapy or hormonal therapy ‐ on managing the following side effects in women with non‐metastatic (stages I to III) breast cancer:

• fatigue,

• weight gain,

• emotional distress,

• nausea and/or vomiting,

• muscle weakness,

• supression of immune functioning.