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Cochrane Database of Systematic Reviews Protocol - Intervention

Hormonal versus non‐hormonal contraceptives in women with diabetes mellitus

This is not the most recent version

Abstract

This is a protocol for a Cochrane Review (Intervention). The objectives are as follows:

Primary objective:
To investigate whether progestogen‐only contraceptive methods and combined estrogen/progestogen contraceptives, respectively, differ from non‐hormonal contraceptives in terms of efficacy in preventing pregnancy and in their side effects on carbohydrate metabolism, lipid metabolism, and haemostatic function when used by women with diabetes mellitus.

Secondary objectives:

  • To investigate whether there are any differences in terms of efficacy in preventing pregnancy and/or side effects on carbohydrate metabolism, lipid metabolism, and haemostatic function of combined oral contraceptive pills containing <50 µg estrogen as compared to combined oral contraceptive pills containing >= 50 µg estrogen when used by women with diabetes mellitus.

  • To investigate whether there are any differences in terms of efficacy in preventing pregnancy and/or side effects on carbohydrate metabolism, lipid metabolism, and haemostatic function between first‐, second‐ and third‐generation progestogen components in oral contraceptives used by women with diabetes mellitus.

  • To assess serious adverse events (thrombosis, myocard infarct, etc.) associated with the use of hormonal contraceptives by women with diabetes mellitus.