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Cochrane Database of Systematic Reviews

PCSK9 inhibition for primary prevention of ischaemic heart disease in heterozygous familial hypercholesterolaemia

Information

DOI:
https://doi.org/10.1002/14651858.CD012917Copy DOI
Database:
  1. Cochrane Database of Systematic Reviews
Version published:
  1. 09 January 2018see what's new
Type:
  1. Intervention
Stage:
  1. Protocol
Cochrane Editorial Group:
  1. Cochrane Cystic Fibrosis and Genetic Disorders Group

Copyright:
  1. Copyright © 2018 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.

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Authors

  • Aidan Ryan

    Correspondence to: Department of Clinical Biochemistry, University Hospital Southampton NHS Foundation Trust, Southampton, UK

    [email protected]

  • Sarah J Nevitt

    Department of Biostatistics, University of Liverpool, Liverpool, UK

  • Christopher D Byrne

    Human Development and Health Academic Unit, Faculty of Medicine, University of Southampton Institute of Developmental Sciences (IDS Building), Southampton, UK

  • Paul Cook

    Department of Clinical Biochemistry, University Hospital Southampton NHS Foundation Trust, Southampton, UK

Contributions of authors

AR drafted the protocol with input from the remaining authors.

Sources of support

Internal sources

  • No sources of support supplied

External sources

  • National Institute for Health Research, UK.

    This systematic review was supported by the National Institute for Health Research, via Cochrane Infrastructure funding to the Cochrane Cystic Fibrosis and Genetic Disorders Group.

Declarations of interest

All authors: none known.

Acknowledgements

This project was supported by the National Institute for Health Research, via Cochrane Infrastructure funding to the Cochrane Cystic Fibrosis and Genetic Disorders Group. The views and opinions expressed therein are those of the authors and do not necessarily reflect those of the Systematic Reviews Programme, NIHR, NHS or the Department of Health.

Version history

Published

Title

Stage

Authors

Version

2018 Jan 09

PCSK9 inhibition for primary prevention of ischaemic heart disease in heterozygous familial hypercholesterolaemia

Protocol

Aidan Ryan, Sarah J Nevitt, Christopher D Byrne, Paul Cook

https://doi.org/10.1002/14651858.CD012917

PICOs

Population
Intervention
Comparison
Outcome

The PICO model is widely used and taught in evidence-based health care as a strategy for formulating questions and search strategies and for characterizing clinical studies or meta-analyses. PICO stands for four different potential components of a clinical question: Patient, Population or Problem; Intervention; Comparison; Outcome.

See more on using PICO in the Cochrane Handbook.