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Cochrane Database of Systematic Reviews

Comparison of different platelet transfusion thresholds prior to insertion of central lines in patients with thrombocytopenia

Information

DOI:
https://doi.org/10.1002/14651858.CD011771.pub2Copy DOI
Database:
  1. Cochrane Database of Systematic Reviews
Version published:
  1. 02 December 2015see what's new
Type:
  1. Intervention
Stage:
  1. Review
Cochrane Editorial Group:
  1. Cochrane Haematology Group

Copyright:
  1. Copyright © 2015 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.

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Authors

  • Lise J Estcourt

    Correspondence to: Haematology/Transfusion Medicine, NHS Blood and Transplant, Oxford, UK

    [email protected]

    [email protected]

  • Michael JR Desborough

    Haematology/Transfusion Medicine, NHS Blood and Transplant, Oxford, UK

  • Sally Hopewell

    Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS), University of Oxford, Oxford, UK

  • Carolyn Doree

    Systematic Review Initiative, NHS Blood and Transplant, Oxford, UK

  • Simon J Stanworth

    National Institute for Health Research (NIHR) Oxford Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust and University of Oxford, Oxford, UK

Contributions of authors

Lise Estcourt: protocol development, searching, selection of studies, eligibility and quality assessment, data extraction and analysis

and content expert.

Michael Desborough: protocol development, searching, selection of studies, eligibility and quality assessment, data extraction and analysis and content expert.

Sally Hopewell: protocol development and methodological expert.

Carolyn Doree: protocol development, searching and selection of studies.

Simon Stanworth: protocol development and content expert.

Sources of support

Internal sources

  • NHS Blood and Transplant, Research and Development, UK

    Funds the work of the Systematic Review Initiative (SRI)

External sources

  • Cochrane Haematological Malignancies Group, Department for Internal Medicine, Germany

    Editorial support

  • National Institute for Health Research (NIHR) Cochrane Programme Grant, UK

    Provides funding for systematic reviewers and methodological support from the Centre for Statistics in Medicine, Oxford

Declarations of interest

Lise Estcourt: partly funded by the NIHR Cochrane Programme Grant ‐ Safe and Appropriate Use of Blood Components.
Michael Desborough: none known.
Sally Hopewell: partly funded by the NIHR Cochrane Programme Grant ‐ Safe and Appropriate Use of Blood Components.

Carolyn Doree: none known.

Simon Stanworth: none known.

Acknowledgements

We thank the editorial base of the Cochrane Haematological Malignancies Review Group.

We thank the National Institute of Health Research (NIHR). This review is part of a series of reviews that have been funded by the NIHR Cochrane Programme Grant ‐ Safe and Appropriate Use of Blood Components. This research was also supported by the NIHR Oxford Biomedical Research Centre Programme.The views expressed are those of the author(s) and not necessarily those of the NHS, the NIHR or the Department of Health.

We thank Marialena Trivella who was an author of the protocol.

Version history

Published

Title

Stage

Authors

Version

2015 Dec 02

Comparison of different platelet transfusion thresholds prior to insertion of central lines in patients with thrombocytopenia

Review

Lise J Estcourt, Michael JR Desborough, Sally Hopewell, Carolyn Doree, Simon J Stanworth

https://doi.org/10.1002/14651858.CD011771.pub2

2015 Jun 23

Comparison of different platelet transfusion thresholds prior to insertion of central lines in patients with thrombocytopenia

Protocol

Lise J Estcourt, Michael Desborough, Sally Hopewell, Marialena Trivella, Carolyn Doree, Simon Stanworth

https://doi.org/10.1002/14651858.CD011771

Differences between protocol and review

There are several differences between the protocol (Estcourt 2015) and this review due to lack of data.

There were no completed studies and therefore we could not:

  • Report on any of the primary or secondary outcomes of the review.

  • Perform a 'Risk of bias' assessment.

  • Assess the quality of the evidence or produce a 'Summary of findings' table.

  • Assess publication bias.

  • Perform any analyses or subgroup analyses.

Notes

This review was a rapid review (definition of a rapid review as previously agreed with the Cochrane Haematological Malignancies Group), we only included English language publications. No relevant non‐English language reports were identified during the searches.

Keywords

MeSH

PICOs

Population
Intervention
Comparison
Outcome

The PICO model is widely used and taught in evidence-based health care as a strategy for formulating questions and search strategies and for characterizing clinical studies or meta-analyses. PICO stands for four different potential components of a clinical question: Patient, Population or Problem; Intervention; Comparison; Outcome.

See more on using PICO in the Cochrane Handbook.

Study flow diagram.

Figures and Tables -
Figure 1

Study flow diagram.