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Cochrane Database of Systematic Reviews

Farmacoterapia combinada para el tratamiento del dolor neuropático en adultos

Information

DOI:
https://doi.org/10.1002/14651858.CD008943.pub2Copy DOI
Database:
  1. Cochrane Database of Systematic Reviews
Version published:
  1. 11 July 2012see what's new
Type:
  1. Intervention
Stage:
  1. Review
Cochrane Editorial Group:
  1. Cochrane Pain, Palliative and Supportive Care Group

Copyright:
  1. Copyright © 2012 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.

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Authors

  • Luis Enrique Chaparro

    Anesthesiology Department, Hospital Pablo Tobon Uribe, Medellin, Colombia

  • Philip J Wiffen

    Thame, UK

  • R Andrew Moore

    Plymouth, UK

  • Ian Gilron

    Correspondence to: Departments of Anesthesiology & Perioperative Medicine & Biomedical & Molecular Sciences, Queen's University, Kingston, Canada

    [email protected]

Contributions of authors

The title was registered by IG. The protocol was developed and written by IG, PW and RAM. IG and LC assessed inclusion of papers and extracted data. LC and IG assumed responsibility for the full review, and write up of the review. PW and RAM contributed to the final draft and approved the final version. LC and IG will be responsible for updating the review.

Sources of support

Internal sources

  • UK Cochrane Centre, UK

    UK sabbatical residence for IG

External sources

  • Canadian Institutes of Health Grant #MCT‐94187 and #MSH‐55041 to IG, Canada

  • IASP J.J. Bonica Trainee Fellowship to LC, USA

Declarations of interest

In the past five years, IG and RAM have consulted for various pharmaceutical companies. In the past five years, IG and RAM have received lecture fees from pharmaceutical companies that market analgesics and other healthcare interventions. IG and RAM have received research support from charities, government and industry sources at various times, but no such support was received for this work.

Two of the studies included in this review were authored by one of the review authors (IG).

LC has no conflicts to declare.

Acknowledgements

  • Nuffield Division of Anaesthetics, Oxford University

  • Oxford Pain Relief Trust

  • Queen's University, Kingston, Ontario, Canada

  • Royal College of Physicians and Surgeons of Canada

  • IASP John Bonica Trainee Fellowship to LEC

Version history

Published

Title

Stage

Authors

Version

2012 Jul 11

Combination pharmacotherapy for the treatment of neuropathic pain in adults

Review

Luis Enrique Chaparro, Philip J Wiffen, R Andrew Moore, Ian Gilron

https://doi.org/10.1002/14651858.CD008943.pub2

2011 Jan 19

Combination pharmacotherapy for the treatment of neuropathic pain in adults

Protocol

Ian Gilron, Philip J Wiffen, R Andrew Moore

https://doi.org/10.1002/14651858.CD008943

Differences between protocol and review

In addition to the pre‐planned literature search, we further searched the clinical trials.gov and controlled‐trials.com trial databases for completed pharmaceutical industry trials which posted their results on the clinicalstudyresults.org website. We performed a snowballing search to increase the accuracy of the protocol‐defined search (Greenhalgh 2005). Given recent updates to the neuropathic pain literature, we also made some revisions to the background section.

Notes

Assessed for updating in 2017

We performed a full search in May 2017 but we did not identify any potentially relevant studies likely to change the conclusions. Therefore, this review has now been stabilised following discussion with the authors and editors. If appropriate, we will update the review if new evidence likely to change the conclusions is published, or if standards change substantially which necessitate major revisions.

Assessed for updating in 2020

At June 2020 we are not aware of any potentially relevant studies likely to change the conclusions. Therefore, this review has now been stabilised following discussion with the authors and editors. The review will be assessed for updating in five years. If appropriate we will update the review before this date if new evidence likely to change the conclusions is published, or if standards change substantially which necessitates major revisions.

PICOs

Population
Intervention
Comparison
Outcome

The PICO model is widely used and taught in evidence-based health care as a strategy for formulating questions and search strategies and for characterizing clinical studies or meta-analyses. PICO stands for four different potential components of a clinical question: Patient, Population or Problem; Intervention; Comparison; Outcome.

See more on using PICO in the Cochrane Handbook.