Scolaris Content Display Scolaris Content Display

Comparison 1 Vitamin D versus placebo, Outcome 1 Serum calcium change (mmol/L).
Figures and Tables -
Analysis 1.1

Comparison 1 Vitamin D versus placebo, Outcome 1 Serum calcium change (mmol/L).

Comparison 1 Vitamin D versus placebo, Outcome 2 Vitamin D level (25‐OHD) pg/ml.
Figures and Tables -
Analysis 1.2

Comparison 1 Vitamin D versus placebo, Outcome 2 Vitamin D level (25‐OHD) pg/ml.

Comparison 1 Vitamin D versus placebo, Outcome 3 Vitamin D level (1, 25 (OH)2 D) pg/ml.
Figures and Tables -
Analysis 1.3

Comparison 1 Vitamin D versus placebo, Outcome 3 Vitamin D level (1, 25 (OH)2 D) pg/ml.

Comparison 1 Vitamin D versus placebo, Outcome 4 Parathyroid hormone levels (change from baseline).
Figures and Tables -
Analysis 1.4

Comparison 1 Vitamin D versus placebo, Outcome 4 Parathyroid hormone levels (change from baseline).

Comparison 1 Vitamin D versus placebo, Outcome 5 Parathyroid hormone levels (pg/ml) (absolute).
Figures and Tables -
Analysis 1.5

Comparison 1 Vitamin D versus placebo, Outcome 5 Parathyroid hormone levels (pg/ml) (absolute).

Comparison 2 Post‐hoc analysis: Bone mineral density, Outcome 1 Whole body bone mineral content (% change).
Figures and Tables -
Analysis 2.1

Comparison 2 Post‐hoc analysis: Bone mineral density, Outcome 1 Whole body bone mineral content (% change).

Comparison 2 Post‐hoc analysis: Bone mineral density, Outcome 2 Lumbar spine z score.
Figures and Tables -
Analysis 2.2

Comparison 2 Post‐hoc analysis: Bone mineral density, Outcome 2 Lumbar spine z score.

Comparison 2 Post‐hoc analysis: Bone mineral density, Outcome 3 Lumbar spine bone mineral density (% change).
Figures and Tables -
Analysis 2.3

Comparison 2 Post‐hoc analysis: Bone mineral density, Outcome 3 Lumbar spine bone mineral density (% change).

Comparison 2 Post‐hoc analysis: Bone mineral density, Outcome 4 Hip bone mineral density (% change).
Figures and Tables -
Analysis 2.4

Comparison 2 Post‐hoc analysis: Bone mineral density, Outcome 4 Hip bone mineral density (% change).

Comparison 2 Post‐hoc analysis: Bone mineral density, Outcome 5 Distal forearm bone mineral density (% change).
Figures and Tables -
Analysis 2.5

Comparison 2 Post‐hoc analysis: Bone mineral density, Outcome 5 Distal forearm bone mineral density (% change).

Comparison 1. Vitamin D versus placebo

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Serum calcium change (mmol/L) Show forest plot

1

Mean Difference (Fixed, 95% CI)

Totals not selected

2 Vitamin D level (25‐OHD) pg/ml Show forest plot

2

Mean Difference (IV, Fixed, 95% CI)

Subtotals only

2.1 Up to 12 months

2

41

Mean Difference (IV, Fixed, 95% CI)

‐2.79 [‐7.25, 1.67]

3 Vitamin D level (1, 25 (OH)2 D) pg/ml Show forest plot

1

Mean Difference (IV, Fixed, 95% CI)

Totals not selected

3.1 Up to 12 months

1

Mean Difference (IV, Fixed, 95% CI)

0.0 [0.0, 0.0]

4 Parathyroid hormone levels (change from baseline) Show forest plot

1

Mean Difference (Fixed, 95% CI)

Totals not selected

5 Parathyroid hormone levels (pg/ml) (absolute) Show forest plot

1

Mean Difference (IV, Fixed, 95% CI)

Totals not selected

5.1 Up to 12 months

1

Mean Difference (IV, Fixed, 95% CI)

0.0 [0.0, 0.0]

Figures and Tables -
Comparison 1. Vitamin D versus placebo
Comparison 2. Post‐hoc analysis: Bone mineral density

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Whole body bone mineral content (% change) Show forest plot

1

Mean Difference (IV, Fixed, 95% CI)

Totals not selected

1.1 Up to 12 months

1

Mean Difference (IV, Fixed, 95% CI)

0.0 [0.0, 0.0]

2 Lumbar spine z score Show forest plot

1

Mean Difference (IV, Fixed, 95% CI)

Totals not selected

2.1 Up to 12 months

1

Mean Difference (IV, Fixed, 95% CI)

0.0 [0.0, 0.0]

3 Lumbar spine bone mineral density (% change) Show forest plot

1

Mean Difference (Fixed, 95% CI)

Totals not selected

3.1 Up to 12 months

1

Mean Difference (Fixed, 95% CI)

0.0 [0.0, 0.0]

4 Hip bone mineral density (% change) Show forest plot

1

Mean Difference (Fixed, 95% CI)

Totals not selected

5 Distal forearm bone mineral density (% change) Show forest plot

1

Mean Difference (Fixed, 95% CI)

Totals not selected

Figures and Tables -
Comparison 2. Post‐hoc analysis: Bone mineral density