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Cochrane Database of Systematic Reviews

Cyclobenzaprine for the treatment of myofascial pain in temporomandibular disorders

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Information

DOI:
https://doi.org/10.1002/14651858.CD006830Copy DOI
Database:
  1. Cochrane Database of Systematic Reviews
Version published:
  1. 17 October 2007see what's new
Type:
  1. Intervention
Stage:
  1. Protocol
Cochrane Editorial Group:
  1. Cochrane Pain, Palliative and Supportive Care Group

Copyright:
  1. Copyright © 2008 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.

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Authors

  • Frederico MG Leite

    Correspondence to: Belo Horizonte, Brazil

    [email protected]

  • Álvaro N Atallah

    Director of Brazilian Cochrane Centre, Universidade Federal de São Paulo / Escola Paulista de Medicina, São Paulo, Brazil

  • Regina P El Dib

    Universidade Federal de São Paulo, São Paulo, Brazil

  • Eduardo Grossmann

    Basics Sciences of Health Institute and Department of Sciences, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil

  • Eduardo Januzzi

    Urgency Medicine and Evidence‐Based Medicine Department, Universidade Federal de Sao Paulo (UNIFESP), Sete Lagoas, Sao Paulo, Brazil

Contributions of authors

Conceived the review: Frederico Mota Gonçalves Leite (FMGL)
Co‐ordinating the review: Álvaro Nagib Atallah (ANA)
Undertaking manual searches: FMGL and Eduardo Januzzi (EJ)
Screening search results: FMGL and EJ
Organising retrieval of papers: FMGL and EJ
Screening retrieved papers: FMGL
Appraising quality of papers: FMGL and EJ
Abstracting data from papers: FMGL, EJ and Regina El Dib (RED)
Writing to authors of papers for additional information: FMGL
Providing additional data about papers: FMGL, EJ and Eduardo Grossmann (EG)
Obtaining and screening data on unpublished studies: FMGL, RED, EJ
Data management for the review: FMGL
Entering data into Review Manager (RevMan 4.2): FMGL
RevMan statistical data: FMGL and RED
Other statistical analysis not using RevMan: FMGL and RED
Double entry of data: (data entered by person one: FMGL; data entered by person two: EJ
Interpretation of data: FMGL, EJ and RED
Statistical analysis: FMGL, RED and ANA
Writing the review: FMGL
Performing previous research that was the foundation of the present review: FMGL
Guarantor for the review (one author): FMGL
Responsible for reading and checking review before submission: FMGL, ANA, EJ and RED

Declarations of interest

None known

Version history

Published

Title

Stage

Authors

Version

2009 Jul 08

Cyclobenzaprine for the treatment of myofascial pain in adults

Review

Frederico MG Leite, Álvaro N Atallah, Regina El Dib, Eduardo Grossmann, Eduardo Januzzi, Regis B Andriolo, Edina MK da Silva

https://doi.org/10.1002/14651858.CD006830.pub3

2008 Apr 23

Cyclobenzaprine for the treatment of myofascial pain in adults

Protocol

Frederico MG Leite, Álvaro N Atallah, Regina El Dib, Eduardo Grossmann, Eduardo Januzzi, Régis B Andriolo, Edina MK da Silva

https://doi.org/10.1002/14651858.CD006830.pub2

2007 Oct 17

Cyclobenzaprine for the treatment of myofascial pain in temporomandibular disorders

Protocol

Frederico MG Leite, Álvaro N Atallah, Regina P El Dib, Eduardo Grossmann, Eduardo Januzzi

https://doi.org/10.1002/14651858.CD006830

Keywords

MeSH

PICOs

Population
Intervention
Comparison
Outcome

The PICO model is widely used and taught in evidence-based health care as a strategy for formulating questions and search strategies and for characterizing clinical studies or meta-analyses. PICO stands for four different potential components of a clinical question: Patient, Population or Problem; Intervention; Comparison; Outcome.

See more on using PICO in the Cochrane Handbook.

Table 1. Search strategy ‐ types of studies

PUBMED

EMBASE

LILACS

CENTRAL

#1 MYOFASCIAL PAIN SYNDROMES [MeSH]
#2 TEMPOROMANDIBULAR JOINT DISORDERS [MeSH]
#3 ("myofascial pain" OR (jaw* AND pain*))
#4 ((Temporomandibular joint* or "temporo‐mandibular joint*" or "TMJ") AND pain*)
#5 (myofascial AND ("trigger point" or trigger‐point*))
#6 #1 or #2 or #3 or #4 or #5
#7 (cyclobenzaprine OR "cyclobenzaprine hydrochloride" OR Aripiprazole OR "Dorixina relax" OR Flexeril OR Lisseril OR Miosan OR Mirtax OR Fexmid OR Flexeril OR Flexiban OR Flexitec OR Gen‐Cyclobenzaprine OR Masterelax OR Medarex OR Med Cyclobenzaprine OR Miosan OR Mirtax OR Nostaden OR Novo‐Cycloprine OR Amrix OR Apo‐Cyclobenzaprine OR Ciclamil OR Ratio‐Cyclobenzaprine OR Reflexan OR Relexil OR Riva‐Cycloprine OR Tensamon OR Tensamox OR Tensiomax OR Tensodox OR Tonalgen OR Yuredol OR Yurelax OR Ziclob))
#8 #6 AND #7

1. MYOFASCIAL PAIN SYNDROME [EMTREE term]
2. TEMPOROMANDIBULAR JOINT DISORDER [EMTREE term]
3. ("myofascial pain" or (jaw$ adj5 pain$))
4. ((Temporomandibular joint$ or "temporo‐mandibular joint$" or "TMJ") AND pain$)
5. (myofascial AND ("trigger point$" or trigger‐point$))
6.OR/1‐5
7. (cyclobenzaprine OR "cyclobenzaprine hydrochloride" OR Aripiprazole OR "Dorixina relax" OR Flexeril OR Lisseril OR Dibenzocycloheptenes OR Miosan OR Mirtax OR Fexmid OR Flexeril OR Flexiban OR Flexitec OR Gen‐Cyclobenzaprine OR Masterelax OR Medarex OR Med Cyclobenzaprine OR Miosan OR Mirtax OR Nostaden OR Novo‐Cycloprine OR Amrix OR Apo‐Cyclobenzaprine OR Ciclamil OR Ratio‐Cyclobenzaprine OR Reflexan OR Relexil OR Riva‐Cycloprine OR Tensamon OR Tensamox OR Tensiomax OR Tensodox OR Tonalgen OR Yuredol OR Yurelax OR Ziclob)
8. 6 AND 7

(Mh random allocation) OR (Mh double blind method) OR (Mh single blind method) AND NOT (Ct animal) AND NOT (Ct human and Ct animal) OR (Pt clinical trial) OR (Ex E05.318.760.535$) OR (Tw clin$) AND (Tw trial$) OR (Tw ensa$) OR (Tw estud$) OR (Tw experim$) OR (Tw investiga$) OR (Tw singl$) OR (Tw simple$) OR (Tw doubl$) OR (Tw doble$) OR (Tw duplo$) OR (Tw trebl$) OR (Tw trip$) AND (Tw blind$) OR (Tw cego$) OR (Tw ciego$) OR (Tw mask$) OR (Tw mascar$) OR (Mh placebos) OR (Tw placebo$) OR (Tw random$) OR (Tw randon$) OR (Tw casual$) OR (Tw acaso$) OR (Tw azar) OR (Tw aleator$) OR (Mh research design) AND NOT (Ct animal) AND NOT (Ct human and Ct animal) OR (Ct comparative study) OR (Ex E05.337$) OR (Mh follow‐up studies) OR (Mh prospective studies) OR (Tw control$) OR (Tw prospectiv$) OR (Tw volunt$) OR (Tw volunteer$) AND NOT ((Ct animal) AND NOT (Ct human and Ct animal))

# Exp MYOFASCIAL PAIN SYNDROMES
#2 ("myofascial pain" OR (jaw* NEAR pain*))
#3 ((Temporomandibular joint* or "temporo‐mandibular joint*" or "TMJ") AND pain*)
#4 (myofascial AND ("trigger point" or trigger‐point*))
#5 Exp TEMPOROMANDIBULAR JOINT DISORDERS
#6 #1 or #2 or #3 or #4 or #5
#7 (cyclobenzaprine OR "cyclobenzaprine hydrochloride" OR Aripiprazole OR "Dorixina relax" OR Flexeril OR Lisseril OR Dibenzocycloheptenes OR Miosan OR Mirtax OR Fexmid OR Flexeril OR Flexiban OR Flexitec OR Gen‐Cyclobenzaprine OR Masterelax OR Medarex OR Med Cyclobenzaprine OR Miosan OR Mirtax OR Nostaden OR Novo‐Cycloprine OR Amrix OR Apo‐Cyclobenzaprine OR Ciclamil OR Ratio‐Cyclobenzaprine OR Reflexan OR Relexil OR Riva‐Cycloprine OR Tensamon OR Tensamox OR Tensiomax OR Tensodox OR Tonalgen OR Yuredol OR Yurelax OR Ziclob)
#8 #6 AND #7

Figures and Tables -
Table 1. Search strategy ‐ types of studies