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Forest plot of comparison 1: glutamine supplementation (parenteral or enteral) versus no supplementation, outcome 1.1: death prior to hospital discharge.
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Figure 1

Forest plot of comparison 1: glutamine supplementation (parenteral or enteral) versus no supplementation, outcome 1.1: death prior to hospital discharge.

Forest plot of comparison 1: glutamine supplementation (parenteral or enteral) versus no supplementation, outcome 1.2: incidence of invasive infection.
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Figure 2

Forest plot of comparison 1: glutamine supplementation (parenteral or enteral) versus no supplementation, outcome 1.2: incidence of invasive infection.

Forest plot of comparison 1: glutamine supplementation (parenteral or enteral) versus no supplementation, outcome 1.3: weight gain during trial period (g/day).
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Figure 3

Forest plot of comparison 1: glutamine supplementation (parenteral or enteral) versus no supplementation, outcome 1.3: weight gain during trial period (g/day).

Comparison 1 Glutamine supplementation (parenteral or enteral) versus no supplementation, Outcome 1 Death prior to hospital discharge.
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Analysis 1.1

Comparison 1 Glutamine supplementation (parenteral or enteral) versus no supplementation, Outcome 1 Death prior to hospital discharge.

Comparison 1 Glutamine supplementation (parenteral or enteral) versus no supplementation, Outcome 2 Incidence of invasive infection.
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Analysis 1.2

Comparison 1 Glutamine supplementation (parenteral or enteral) versus no supplementation, Outcome 2 Incidence of invasive infection.

Comparison 1 Glutamine supplementation (parenteral or enteral) versus no supplementation, Outcome 3 Weight gain during trial period (g/day).
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Analysis 1.3

Comparison 1 Glutamine supplementation (parenteral or enteral) versus no supplementation, Outcome 3 Weight gain during trial period (g/day).

Comparison 1. Glutamine supplementation (parenteral or enteral) versus no supplementation

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Death prior to hospital discharge Show forest plot

3

263

Risk Ratio (M‐H, Fixed, 95% CI)

0.79 [0.19, 3.20]

2 Incidence of invasive infection Show forest plot

3

263

Risk Ratio (M‐H, Fixed, 95% CI)

1.37 [0.89, 2.11]

3 Weight gain during trial period (g/day) Show forest plot

1

20

Mean Difference (IV, Fixed, 95% CI)

3.80 [‐6.65, 14.25]

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Comparison 1. Glutamine supplementation (parenteral or enteral) versus no supplementation