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Methodological quality summary: review authors' judgements about each methodological quality item for each included study.
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Figure 1

Methodological quality summary: review authors' judgements about each methodological quality item for each included study.

Five studies showing percentage improvement (any definition) with carbamazepine (any dose) and placebo. Size of the study is proportional to the size of the symbol (inset scale). Yellow symbols = trigeminal neuralgia , blue = painful diabetic neuropathy, red = post stroke pain
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Figure 2

Five studies showing percentage improvement (any definition) with carbamazepine (any dose) and placebo. Size of the study is proportional to the size of the symbol (inset scale). Yellow symbols = trigeminal neuralgia , blue = painful diabetic neuropathy, red = post stroke pain

Forest plot of comparison: 1 Carbamazepine in neuropathic pain, outcome: 1.1 Any pain improvement.
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Figure 3

Forest plot of comparison: 1 Carbamazepine in neuropathic pain, outcome: 1.1 Any pain improvement.

Comparison 1 Carbamazepine in neuropathic pain, Outcome 1 Any pain improvement.
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Analysis 1.1

Comparison 1 Carbamazepine in neuropathic pain, Outcome 1 Any pain improvement.

Comparison 1 Carbamazepine in neuropathic pain, Outcome 2 At least 1 adverse event.
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Analysis 1.2

Comparison 1 Carbamazepine in neuropathic pain, Outcome 2 At least 1 adverse event.

Comparison 1. Carbamazepine in neuropathic pain

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Any pain improvement Show forest plot

5

298

Risk Ratio (M‐H, Fixed, 95% CI)

6.13 [3.89, 9.65]

1.1 Trigeminal neuralgia

3

208

Risk Ratio (M‐H, Fixed, 95% CI)

5.87 [3.58, 9.61]

1.2 Painful diabetic neuropathy

1

60

Risk Ratio (M‐H, Fixed, 95% CI)

8.5 [2.15, 33.62]

1.3 Central post stroke pain

1

30

Risk Ratio (M‐H, Fixed, 95% CI)

5.0 [0.66, 37.85]

2 At least 1 adverse event Show forest plot

4

346

Risk Ratio (M‐H, Fixed, 95% CI)

2.40 [1.85, 3.12]

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Comparison 1. Carbamazepine in neuropathic pain