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Methodological quality graph: review authors' judgements about each methodological quality item presented as percentages across all included studies.
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Figure 1

Methodological quality graph: review authors' judgements about each methodological quality item presented as percentages across all included studies.

Methodological quality summary: review authors' judgements about each methodological quality item for each included study.
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Figure 2

Methodological quality summary: review authors' judgements about each methodological quality item for each included study.

Comparison 1 Calcium channel blockers versus control, Outcome 1 Death (all‐cause mortality).
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Analysis 1.1

Comparison 1 Calcium channel blockers versus control, Outcome 1 Death (all‐cause mortality).

Comparison 1 Calcium channel blockers versus control, Outcome 2 Death and severe disability.
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Analysis 1.2

Comparison 1 Calcium channel blockers versus control, Outcome 2 Death and severe disability.

Comparison 1 Calcium channel blockers versus control, Outcome 3 Adverse events.
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Analysis 1.3

Comparison 1 Calcium channel blockers versus control, Outcome 3 Adverse events.

Comparison 1 Calcium channel blockers versus control, Outcome 4 Hypotension.
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Analysis 1.4

Comparison 1 Calcium channel blockers versus control, Outcome 4 Hypotension.

Comparison 1 Calcium channel blockers versus control, Outcome 5 Mortality (by participant subgroups).
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Analysis 1.5

Comparison 1 Calcium channel blockers versus control, Outcome 5 Mortality (by participant subgroups).

Comparison 1 Calcium channel blockers versus control, Outcome 6 Death and severe disability (by participant subgroups).
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Analysis 1.6

Comparison 1 Calcium channel blockers versus control, Outcome 6 Death and severe disability (by participant subgroups).

Comparison 1. Calcium channel blockers versus control

Outcome or subgroup title

No. of studies

No. of participants

Statistical method

Effect size

1 Death (all‐cause mortality) Show forest plot

5

1337

Peto Odds Ratio (Peto, Fixed, 95% CI)

0.91 [0.70, 1.16]

1.1 Nicardipine

2

46

Peto Odds Ratio (Peto, Fixed, 95% CI)

1.0 [0.20, 4.90]

1.2 Nimodipine

3

1291

Peto Odds Ratio (Peto, Fixed, 95% CI)

0.90 [0.70, 1.17]

2 Death and severe disability Show forest plot

5

1838

Peto Odds Ratio (Peto, Fixed, 95% CI)

0.97 [0.81, 1.18]

2.1 Nicardipine

1

22

Peto Odds Ratio (Peto, Fixed, 95% CI)

0.25 [0.05, 1.27]

2.2 Nimodipine

4

1816

Peto Odds Ratio (Peto, Fixed, 95% CI)

0.99 [0.82, 1.20]

3 Adverse events Show forest plot

3

1324

Peto Odds Ratio (Peto, Fixed, 95% CI)

1.15 [0.87, 1.52]

3.1 Nicardipine

0

0

Peto Odds Ratio (Peto, Fixed, 95% CI)

0.0 [0.0, 0.0]

3.2 Nimodipine

3

1324

Peto Odds Ratio (Peto, Fixed, 95% CI)

1.15 [0.87, 1.52]

4 Hypotension Show forest plot

3

1324

Peto Odds Ratio (Peto, Fixed, 95% CI)

1.74 [1.20, 2.52]

4.1 Nicardipine

0

0

Peto Odds Ratio (Peto, Fixed, 95% CI)

0.0 [0.0, 0.0]

4.2 Nimodipine

3

1324

Peto Odds Ratio (Peto, Fixed, 95% CI)

1.74 [1.20, 2.52]

5 Mortality (by participant subgroups) Show forest plot

4

Peto Odds Ratio (Peto, Fixed, 95% CI)

Subtotals only

5.1 tSAH

2

331

Peto Odds Ratio (Peto, Fixed, 95% CI)

0.59 [0.37, 0.94]

5.2 no tSAH

3

984

Peto Odds Ratio (Peto, Fixed, 95% CI)

1.13 [0.83, 1.54]

6 Death and severe disability (by participant subgroups) Show forest plot

3

Peto Odds Ratio (Peto, Fixed, 95% CI)

Subtotals only

6.1 tSAH

3

460

Peto Odds Ratio (Peto, Fixed, 95% CI)

0.67 [0.46, 0.98]

6.2 no tSAH

2

831

Peto Odds Ratio (Peto, Fixed, 95% CI)

1.02 [0.77, 1.36]

Figures and Tables -
Comparison 1. Calcium channel blockers versus control